ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2021 American Transplant Congress

    The Role of the B2 Microglobulin Trend in Patients with Delayed Graft Function After Kidney Transplant

    A. Perez-Gutierrez, P. J. Bachul, B. Juengel, P. Witkowski, D. DiSabato, R. Barth, J. Fung, Y. Becker

    Surgery, University of Chicago, Chicago, IL

    *Purpose: Delayed graft function (DGF) is associated with worse short and long-term outcomes after kidney transplantation. There is a lack of biomarkers to predict outcomes…
  • 2021 American Transplant Congress

    The Role of Donor-derived Cell-free DNA Testing in Detecting Subclinical Kidney Allograft Rejection

    M. Dasari1, J. Hendele2, L. Sibulesky2, N. Leca3

    1Department of Surgery, University of Washington, Seattle, WA, 2Department of Surgery, Division of Transplant, University of Washington, Seattle, WA, 3Department of Nephrology, UW Medicine Kidney and Pancreas Transplantation Program, University of Washington, Seattle, WA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing is an emerging method of non-invasive testing for graft rejection in the field of solid-organ transplantation. We describe how…
  • 2021 American Transplant Congress

    Cellular Landscape of Steatotic Livers Revealed by Single-nuclei Rna Sequencing

    C. Kuscu1, C. Kuscu1, A. Shetty2, E. Bardhi3, T. Rousselle4, J. Eason1, M. Sraj5, D. Maluf6, V. Mas4

    1Surgery, James D Eason Transplant Institute, Memphis, TN, 2University of Maryland, Institute for Genome Sciences, Baltimore, MD, 3Program in Transplantation - University of Maryland, Baltimore, MD, 4Surgery, Division of Surgical Science, Baltimore, MD, 5Surgery, University of Maryland, Baltimore, MD, 6Surgery, Program in Transplantation - University of Maryland, Baltimore, MD

    *Purpose: Hepatic IRI represents a barrier to the use of available organs for transplant, particularly fatty livers. We aimed to discern the cellular subsets and…
  • 2021 American Transplant Congress

    Role of Trugraf Testing in Kidney Allografts Previously Biopsied for Dysfunction

    Y. A. Qazi1, W. Mon1, C. Choi1, S. Qazi2, M. Smogorzewski1

    1Keck Medical Center at USC, Los Angeles, CA, 2Keck Medical Center at USC, La Canada Flt, CA

    *Purpose: TruGraf®, can be used as an alternative to surveillance biopsies for ruling out “silent” subclinical acute rejections in transplant patients with stable graft function.…
  • 2021 American Transplant Congress

    Donor Derived Cell-free DNA Kinetics Early After Kidney Transplant in Patients with Delayed Graft Function Who Received Kidneys from Donation After Cardiac Death Donors

    R. Gumber, M. Abuzeineh, C. Mejia, D. Brennan, F. Naqvi

    Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Delayed graft function (DGF) may reduce long-term kidney allograft survival due to ischemia-reperfusion injury and rejection. Donor Derived Cell-Free DNA (dd-cfDNA) is proposed to…
  • 2021 American Transplant Congress

    Cleveland Clinic Experience with Cadaveric Uterus Transplant

    L. Del Prete1, C. Quintini1, K. Hashimoto1, B. Eghtesad1, G. D'Amico1, C. Kwon1, D. Priebe1, E. Richards1, S. Ricci1, U. Perni1, C. Ferrando1, A. Chiesa-Vottero1, S. Mawhorter1, N. Yeaney1, R. Farrell1, R. Flyckt2, C. Miller1, T. Falcone1, A. Tzakis1

    1Cleveland Clinic, Cleveland, OH, 2University Hospital, Cleveland, OH

    *Purpose: Uterus transplantation (UTx) is the only treatment for women with uterine factor infertility (UFI). The majority of overall experience is from living donation. Little…
  • 2021 American Transplant Congress

    Evaluation of Serum Klotho Levels at Early Kidney Post-Transplant

    T. Vazquez-Sanchez1, J. Alonso-Titos1, M. Sánchez-Niño2, E. Sola1, M. Leon3, V. Lopez1, P. Ruiz-Esteban1, E. Porrini4, A. Ortiz5, D. Hernández1

    1Nephrology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 2Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Madrid, Spain, 3Pathology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 4Nephrology, Hospital Universitario de Canarias, CIBICAN, Universidadde laLaguna, REDinREN (RD16/0009/0031) Tenerife e Instituto Reina Sofía de Investigación Renal (IRSIN), Malaga, Spain, 5Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Malaga, Spain

    *Purpose: Klotho expression is lowered in patients with chronic kidney disease (CKD). After kidney transplant (KT), serum Klotho levels could be significantly increased compared to…
  • 2021 American Transplant Congress

    The Clinical Significance of Preformed Anti-HLA-DQ Donor-specific Antibodies on Allograft Outcomes in Kidney Transplantation

    S. Lee1, C. Yang2, B. Chung2

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of

    *Purpose: De-novo anti-HLA-DQ donor-specific antibody (DSA) has been identified as a risk factor for late graft dysfunction and graft loss in kidney transplantation (KT). The…
  • 2021 American Transplant Congress

    Predicted Heart Mass Difference as a Risk Factor for Severe Primary Graft Dysfunction in the Contemporary Era of Heart Transplantation: A Report from the International Consortium on Primary Graft Dysfunction

    F. Foroutan1, L. K. Truby2, Y. Moayedi1, J. Han3, J. Guzman4, M. Farrero4, E. Baughan5, M. Farr5, H. Zafar6, J. Felius6, J. van Zyl7, D. Law8, S. Chih8, P. Angleitner9, M. Sabatino10, A. DeVore2, R. J. Miller11, L. Potena10, A. Zuckermann9, K. K. Khush3, S. A. Hall6, H. J. Ross1

    1Ted Rogers Centre for Heart Research, Toronto, ON, Canada, 2Duke University School of Medicine, Durham, NC, 3Stanford University, Stanford, CA, 4Clinic Barcelona Hospital Universitari, Barcelona, Spain, 5Columbia University Medical Center, New York, NY, 6Baylor University Medical Center, Dallas, TX, 7Dallas University Medical Center, Dallas, TX, 8University of Ottawa Heart Institute, Ottawa, ON, Canada, 9Medical University of Vienna, Vienna, Austria, 10Bologna University Hospital, Bologna, Italy, 11University of Calgary, Calgary, AB, Canada

    *Purpose: Primary Graft Dysfunction (PGD) increases early mortality after heart transplant (HT). Predicted heart mass (PHM) difference may be a risk factor for PGD. Lack…
  • 2021 American Transplant Congress

    Medical Costs in the Year Following Kidney Transplantation: Relationships with Renal Function and Graft Failure

    M. Cooper1, M. A. Schnitzler2, C. Nilubol1, W. Wang3, X. Zhu3, J. Wu3, R. J. Nordyke4

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Saint Louis University, St. Louis, MO, 3Genesis Research, Hoboken, NJ, 4Angion Biomedica, San Francisco, CA

    *Purpose: We describe relationships between total medical costs in the first year following kidney transplant with overall renal function as measured by: 1) estimated glomerular…
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