Articles tagged "Graft function"

2016 American Transplant Congress
The Intrarenal Resistive Index Measured After Transplantation Is Determined by the Upstream Vascular System of the Recipient.
L. Heylen,¹ M. Naesens,¹ B. Sprangers,¹ S. Heye,² P. Verhamme,³ I. Jochmans,⁴ D. Monbaliu,⁴ J. Pirenne,⁴ D. Kuypers,¹ K. Claes.¹
¹Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium; ²Radiology, University Hospitals Leuven, Leuven, Belgium; ³Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium; ⁴Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
Objective: We recently demonstrated that the renal resistive index, measured after renal transplantation, reflects recipient characteristics, like recipient age and central hemodynamics, and not so…
2016 American Transplant Congress
Predictive Model of Delayed Graft Function in Machine Perfused Kidney Transplantation: Model Validation Using Decision Curve Analysis.
K. Ravindra,¹ S. Sanoff,¹ D. Vikraman,¹ U. Patel,¹ M. Ellis,¹ E. Squires,² D. Sudan,¹ W. Irish.¹
¹Surgery, Duke University, Durham, NC; ²Half Moon Bay, Raleigh.
Introduction: Predictive model for delayed graft function (DGF) was developed (Am J Transpl 2010; 10: 2279–86)excluding organs that were machine perfused (MP). Currently, approximately 50%…
2016 American Transplant Congress
First Bilateral Hand Transplant in a Child: Short-Term Medical Outcomes and Challenges.
S. Amaral,¹ M. Levine,² B. Chang,² S. Lopez,¹ C. McAndrew,² S. Kessler,¹ A. Shaked,² L. Levin.²
¹Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA; ²Surgery, University of Pennsylvania, Philadelphia, PA.
Background: In July 2015, our center successfully performed the first bilateral hand transplant in a pediatric patient in the United States. The recipient was an…
2016 American Transplant Congress
The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.
D. Keith, G. Vranic, A. Nishio Lucar.
University of Virginia, Charlottesville, VA.
Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…
2016 American Transplant Congress
Urinary Expression of miRNA-155, miRNA-210, miRNA-142 and CXCL-10 Production Predicts the Risk of Acute Rejection and Graft Outcome in Renal Transplant Recipients.
O. Millan,¹ K. Budde,² C. Sommerer,³ I. Aliart,¹ O. Rissling,² B. Bardaji,⁴ M. Matz,² M. Zeier,³ I. Silva,⁴ L. Guirado,⁴ M. Brunet.¹
¹Pharmacology Laboratory, CDB, IDIBAPS, Hospital Clinic Barcelona, Barcelona University, Barcelona, Spain; ²Medizinische Klinik mit Schwerpunkt Nephrologie, Charité Universitätsmedizin, Berlin, Germany; ³Department of Nephrology, University Hospital Heidelberg and Mannheim, Heidelberg, Germany; ⁴Renal Transplant Unit, Fundació Puigvert, Barcelona, Spain.
MicroRNAs (miRs) have been reported to play a role in immune system response. The results of several clinical trials have suggested that these molecules might…
2016 American Transplant Congress
Results from 100 Consecutive Donation-After-Circulatory Death (DCD) Liver Transplants Using a Thrombolytic Protocol.
J. Seal, H. Bohorquez, N. Battula, E. Ahmed, D. Bruce, I. Carmody, R. Trevor, G. Tyson, S. Joshi, N. Bzowej, G. Therapondas, N. Girgrah, A. Cohen, G. Loss.
Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.
Background: In early 2010, our center implemented a thrombolytic protocol for DCD liver transplantation in an effort to reduce biliary complications and improve graft survival.…
2016 American Transplant Congress
The Use of Kidneys with Acute Kidney Injury: The Good, the Bad and the Ugly.
C. Boffa,^1,2 F. van de Leemkolk,¹ E. Curnow,³ J. Gilbert,² E. Sharples,^1,2 R. Ploeg.^1,2
¹Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom; ²Oxford Transplant Centre, Oxford University Hospital Trust, Oxford, United Kingdom; ³Department of Statistics, NHS Blood and Transplant, Bristol, United Kingdom.
Introduction:The widening gap between supply and demand in kidney transplantation has lead to the increased use of kidneys from marginal donors, including those with acute…
2016 American Transplant Congress
Hepatic Hemodynamics (HD) and Portal Flow Modulation (PM): Tactical Use in Small for Size (SFS) Live Donor Liver Transplantation (LDLT).
T. Mansour,¹ J. Pisa,¹ E. Przybyszewski,¹ J. Guarrera,¹ K. Tomoaki,¹ B. Samstein,¹ K. Halazun,² A. Griesemer,¹ J. Emond.¹
¹Surgery, Columbia University Medical Center, New York; ²Surgery, Weill Cornell Medical Center, New York.
Objectives:Efforts to reduce the risk of donor hepatectomy have resulted in smaller grafts for transplantation. Grafts below 0.8% of recipient body weight (GW/RW), have been…
2015 American Transplant Congress
Outpatient Management of Delayed Graft Function (DGF) Is Associated With Reduced Length of Stay and Acute Rejection
B. Muth,¹ B. Astor,¹ J. Turk,¹ M. Mohamed,¹ S. Parajuli,¹ D. Kaufman,² D. Mandelbrot,¹ A. Djamali.^1,2
¹Department of Medicine, University of Wisconsin, Madison, WI; ²Department of Surgery, University of Wisconsin, Madison, WI.
Delayed graft function (DGF) increases hospital length of stay (LOS) and risk for readmission, rejection, early graft loss and death. We created a multidisciplinary DGF…
2015 American Transplant Congress
Post-Transplant Changes in Serum Creatinine and Beta-2 Microglobulin Predict Acute Tubular Necrosis in the Early Post-Transplant Period
P. Liu,¹ A. Djamali,^1,2 D. Kaufman,^2,1 B. Astor.¹
¹Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI; ²Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Purpose: To evaluate the utility of early post-transplant changes in serum creatinine (SCr) and beta-2 microglobulin (B2M) in differentiating acute tubular necrosis (ATN) and other…