Articles tagged "Graft function"

2016 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) with a Hemoglobin Based Oxygen Carrier (HBOC) Solution Reprograms Dynamic Inflammation Networks When Compared to Cold Storage (CS) in a Porcine Liver Allograft Model.
D. Sadowsky, R. Zamora, B. Banan, D. Barclay, J. Yin, Y. Vodovotz, P. Fontes.
University of Pittsburgh, Pittsburgh.
Introduction: Inflammatory markers have been mostly studied by standard statistical analysis focused on single component variations. This study aimed to compare SNMP with CS regarding…
2016 American Transplant Congress
Thrombotic Microangiopathy After Kidney Transplantation: A Rare but Serious Complication.
C. Teixeira, I. Pietrobom, A. Lima, N. Tenório, G. Basso, M. Cristelli, L. Viana, G. Kirsztajn, H. Tedesco-Silva, J. Medina-Pestana.
Universidade Federal de São Paulo, São Paulo, Brazil.
Purposes: Study the clinical characteristics of cases with thrombotic microangiopathy (TMA) in the renal allograft, identify the triggers of this disease and determine its impact…
2016 American Transplant Congress
Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.
B. Banan, S. Dobrowolski, G. Michalopoulos, P. Fontes.
University of Pittsburgh, Pittsburgh.
Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…
2016 American Transplant Congress
Treatment of Hepatitis C Viral Infection with Novel Direct Acting Antivirals in Kidney Transplant Recipients – Single Center Experience.
K. Hatahet,¹ M. Ghanta,¹ A. Gillespie,¹ I. Lee,¹ H. El-Halawany,² K. Qureshi,² K. Lau,³ S. Karhadkar,³ A. Di Carlo,³ S. Constantinescu,¹ S. Rao.¹
¹Nephrology, Temple University, Phildelphia, PA; ²Hepatology, Temple University, Philadelphia, PA; ³Surgery, Temple University, Philadelphia, PA.
Kidney transplant recipients (KTRs) with Hepatitis C virus infection (HCV+ve) have higher proteinuria and inferior patient and graft survival compared to HCV negative KTRs. Due…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Donor AKI Does Not Adversely Affect the Outcome Following DCD Kidney Transplant.
I. Qaqish, D. Haakinson, K. Reddy, M. Smith, H. Khamash, R. Heilman.
Mayo Clinic, Phoenix, AZ.
BackgroundTransplanting kidneys from donation after cardiac death (DCD) donors has been associated with good outcome, but the impact of added donor AKI on the outcome…
2016 American Transplant Congress
Prolonged Normothermic Ex Vivo Kidney Perfusion Is a Safe Preservation Technique for Kidney Transplantation: A New Opportunity for the Storage, Assessment and Repair of Kidney Grafts.
J. Kaths,^1,2,3 J. Echeverri,¹ N. Goldaracena,¹ K. Louis,¹ Y.-M. Chun,¹ I. Linares,^1,3 A. Wiebe,¹ P. Yip,⁵ R. John,⁵ I. Mucsi,⁶ A. Ghanekar,¹ D. Bagli,^7,3 D. Grant,¹ L. Robinson,^2,3 M. Selzner.^1,3
¹Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ²Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; ³Institute of Medical Science, University of Toronto, Toronto, ON, Canada; ⁴Department of General, Visceral, and Transplant Surgery, University Medical Center Mainz, Mainz, Germany; ⁵Laboratory Medicine & Pathobiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ⁶Department of Medicine, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ⁷Departments of Surgery (Urology) & Physiology, The Hospital for Sick Children, Toronto, ON, Canada.
Hypothermic kidney storage causes preservation injury. We investigated whether SCS can be safely replaced with prolonged normothermic ex vivo kidney perfusion (NEVKP). Right kidneys were…
2016 American Transplant Congress
Long-Term Renal Allograft Outcome After Parathyroidectomy.
M. Patecki, I. Scheffner, H. Haller, W. Gwinner.
Medical School Hannover, Hannover, Germany.
Parathyroidectomy (PTx) after kidney transplantation (Tx) has been reported to have adverse effects on the allograft. In this study, we analyzed the course of patients…
2016 American Transplant Congress
Non-Invasive – Minimalistic Approach Using Cell-Free MicroRNAs in Paired Plasma and Urine Samples for Early Diagnosis of Chronic Renal Allograft Dysfunction.
S. Bontha,¹ R. Gehrau,¹ E. Rhone,¹ A. King,² L. Gallon,³ K. Brayman,¹ D. Maluf,¹ V. Mas.¹
¹Surgery, UVA, Charlottesville, VA; ²VCU, Richmond; ³NWU, Chicago.
Background: Reducing use of tissue biopsy by efficiently using non-invasive samples for continuous monitoring and evaluation of graft function would be ideal. Reports indicate continuous…
2016 American Transplant Congress
Validation of SUITO Index and C-Peptide/Glucose Creatinine Ratio as Convenient Tools for the Evaluation of the Short and Long-Term Islet Allograft Function.
J. Gołębiewska,¹ J. Solomina,² S. Matosz,² C. Thomas,³ L. Schenck,² K. Golab,² W. Chon,³ S. Ramachandran,² M. Tibudan,² A. Dębska-ŚLizień,¹ B. Rutkowski,¹ P. Witkowski.²
¹Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland; ²Department of Surgery, University of Chicago, Chicago, IL; ³Department of Medicine, University of Chicago, Chicago, IL.
Background: Mixed Meal Tolerance Test (MMTT) together with the beta-score are standard tools to evaluate beta-cell function after islet transplantation but utilization of the test…