ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2017 American Transplant Congress

    Noninvasive Renal Transplant Graft Monitoring in Single Institution Using Cell-Free DNA in Recipient Plasma via Insertion-Deletion Allele Polymorphism.

    Y. Goh,1 S. Ho,2 L. Raman,1 V. Anantharaman,3 T. Goh,3 S. Koay,2 H. Tiong.1

    1Urology, National University Hospital, Singapore, Singapore; 2Laboratory Medicine, National University Hospital, Singapore, Singapore; 3Nephrology, National University Hospital, Singapore, Singapore

    IntroductionThere is an unmet clinical need in renal transplantation towards early detection of donor organ damage. Serum creatinine(SCr) and biopsies are not ideal.Cell-free donor DNA(cfdDNA)…
  • 2017 American Transplant Congress

    Is “Death with a Functioning Graft (DWF)” Really Death with Function? Data from the Long-Term Deterioration of Kidney Allograft Function (DeKAF) Study.

    R. Gaston,1 A. Fieberg,2 L. Hunsicker,3 D. Rush,4 R. Leduc,2 J. Connett,2 A. Matas,2 DeKaf Investigators.

    1UAB, Birmingham, AL; 2U Minnesota, Minneapolis, MN; 3U Iowa, Iowa City, IA; 4U Manitoba, Winnipeg, Canada

    To understand causes of kidney transplant (KT) failure, outcomes are often segregated into death-censored graft failure (DCGF, a proxy for immunologic injury) and DWF. To…
  • 2017 American Transplant Congress

    Delayed Graft Function[mdash]Less Ominous for ARF or DCD Recipients?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    Delayed Graft Function (DGF) is both a transplant outcome and risk factor for graft failure. Kidneys from donors with kidney injury--such as acute renal failure…
  • 2017 American Transplant Congress

    Risk of Kidney Rejection Following Simultaneous Liver Kidney Transplantation.

    S. Shah,1 A. Suddle,1 V. Aluvihare,1 O. Shaw,3 C. Shaw,1 N. Mamode,2 C. Callaghan,2 G. Koffman,2 N. Heaton.1

    1King's College Hospital, London, United Kingdom; 2Guy's and St Thomas' Hospital, London, United Kingdom; 3Viapath, London, United Kingdom

    Introduction: Simultaneous liver kidney transplant (SLK) recipients may be at risk of antibody-mediated kidney rejection (AMR) if the pre-transplant crossmatch is positive (+CXM). Accordingly, in…
  • 2017 American Transplant Congress

    Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.

    N. Celik,1 A. Ganoza,1 G. Bond,1 K. Soltys,1 R. Sindhi,1 P. McKiernan,3 A. Humar,2 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Division of Pediatric Gastroenterology, Pittsburgh, PA

    Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…
  • 2017 American Transplant Congress

    Pre-Transplant Recipient Transcriptomic Profile May Predict Delayed Graft Function (DGF) in Kidney Transplantation.

    P. Pontrelli,1 F. Rascio,2 F. Pesce,1 M. Accetturo,1 G. Castellano,1 G. Zaza,3 A. Lupo,3 M. Fiorentino,1 L. Gesualdo,1 G. Stallone,2 G. Grandaliano.2

    1University of Bari, Bari, Italy; 2University of Foggia, Foggia, Italy; 3University of Verona, Verona, Italy

    Background: DGF is associated with a reduced long-term graft survival. Ischemia-reperfusion damage and donors' features have been always considered as key pathogenic factors in this…
  • 2016 American Transplant Congress

    YKL-40 Predicts Renal Recovery in Deceased-Donor Transplantation.

    J. Puthumana,1 I. Hall,1 P. Reese,2 B. Schröppel,3 F. Weng,4 H. Thiessen-Philbrook,1 M. Doshi,5 V. Rao,1 C. Lee,6 J. Elias,6 L. Cantley,1 C. Parikh.1

    1Yale University School of Medicine, New Haven, CT; 2Renal-Electrolyte and Hypertension Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; 3Section of Nephrology, University Hospital, Ulm, Germany; 4Saint Barnabas Medical Center, Livingston, NJ; 5Division of Nephrology, Wayne State University School of Medicine, Detroit, MI; 6School of Medicine and Biological Sciences, Brown University, Providence, RI.

    Background Deceased-donor kidneys with acute kidney injury (AKI) are often discarded for fear of poor transplantation outcomes. Donor biomarkers that predict post-transplant renal recovery could…
  • 2016 American Transplant Congress

    Association Between GFR Decline and Long Term Outcome in Renal Transplantation.

    A. Delay,1 O. Moranne,2 N. Maillard,1 E. Alamartine,1 C. Mariat.1

    1Nephrology Department, CHU, Saint Etienne, France; 2Nephrology Department, CHU, Nimes, France.

    In renal transplantation, GFR decline is strongly associated to graft failure and patient death and thus could be an interesting proxy for clinical research. GFR…
  • 2016 American Transplant Congress

    IVIG and High Dose Steroid Treatment of Transplant Glomerulopathy Effectively Slows Progression of Loss of Renal Allograft Function.

    K. Sablik,1 C. Looman,2 M. Clahsen-van Groningen,3 J. Damman,3 D. Roelen,4 M. van Agteren,1 M. Betjes.1

    1Nephrology and Transplantation, Erasmus MC University Center, Rotterdam, Netherlands; 2Biostatistics, Erasmus MC University Center, Rotterdam, Netherlands; 3Pathology, Erasmus MC University Center, Rotterdam, Netherlands; 4Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.

    Introduction Transplant glomerulopathy (TG) is commonly associated with chronic antibody mediated rejection and is a major cause of late kidney allograft loss with no established…
  • 2016 American Transplant Congress

    Common Iliac Artery Stenosis: An Often Overlooked Cause of Graft Dysfunction.

    E. Christie, P. Campbell, K. Wen.

    Nephrology, University of Alberta, Edmonton, AB, Canada.

    Transplant renal artery stenosis (TRAS) has been an increasingly recognized complication post kidney transplantation, and a potentially reversible cause for hypertension and allograft dysfunction. This…
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