Articles tagged "Graft function"

2017 American Transplant Congress
Technical Refinement to Prevent Hepatic Outflow Disturbance in Right Lobe Living Donor Liver Transplantation: Simplified One-Orifice Venoplasty.
J. Kim, D. Choi.
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Republic of Korea
Middle hepatic vein (MHV) reconstruction is often essential to avoid hepatic congestion and serious graft dysfunction in living donor liver transplantation (LDLT). The aim of…
2017 American Transplant Congress
Clusterin Levels at 3-Months Associate with DGF and 12-Month Fibrosis – Reinforcing the Early Injury to Fibrosis Continuum.
M. Menon,¹ L. Liriano-Ward,² N. Philippe,¹ C. Wei,¹ W. Zhang,¹ Z. Yi,¹ K. Keung,² P. O'Connell,² B. Murphy.¹
¹Medicine, Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; ²Medicine, Westmead Millenium Institute, Sydney, NSW, Australia
The Genomics of Chronic Allograft Rejection (GoCAR) is a multicenter study investigating the ability of gene expression to predict the development of Chronic allograft nephropathy.…
2017 American Transplant Congress
Nuclear Co-Repressor Complex Inhibition Reverses Benefit of HDAC2 Deletion in Renal Ischemia.
D. Aufhauser Jr,¹ D. Murken,¹ Z. Wang,¹ A. Samanta,² G. Ge,¹ T. Bhatti,³ P. Cole,⁴ J. Kalin,⁴ W. Hancock,^2,3 M. Levine.^1,5
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Pathology, University of Pennsylvania, Philadelphia, PA; ³Pathology, Children's Hospital of Philadelphia, Philadelphia, PA; ⁴Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD; ⁵Surgery, Children's Hospital of Philadelphia, Philadelphia, PA
Introduction: Class I histone/protein deacetylases (HDACs) 1 and 2 bear >85% protein sequence homology and conventionally are thought to have similar function via occupancy in…
2017 American Transplant Congress
Worsening Rather Than Severe Acute Kidney Injury Affects Kidney Transplantation Outcomes.
M.-Y. Yu,¹ B. Yu,² Y. Kim,¹ S. Mi,³ J. Ha,³ J. Yang,³ Y. Kim,¹ H. Lee.¹
¹Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; ²Internal Medicine, Soon Chun Hyang University Bucheon Hospital, Bucheon, Republic of Korea; ³Surgery, Seoul National University Hospital, Seoul, Republic of Korea
BackgroundThe growing evidence has suggested that deceased donor kidneys with acute kidney injury (AKI) may be a good solution to overcome organ shortage. Although previous…
2017 American Transplant Congress
Single-Center, Prospective, Open Label Pilot Study to Investigate the Effectiveness of Everolimus Associated with Mycophenolic Acid and Prednisone in Adult Patients Submitted to an Allograft Renal Transplant with Calcineurin Inhibitor Withdrawl on Week 16th.
L. Giordano,^1,2 M. Lasmar,^1,2 H. Vianna,^1,2 E. Lasmar.^1,2
¹Renal Transplant Unit, Hospital Universitário Ciências Médicas de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; ²Nephrology Department, Rede Mater Dei de Saúde, Belo Horizonte, Minas Gerais, Brazil
Although CI have proven efficacy in kidney transplantation worldwide, they are drugs with nephrotoxic potential and may contribute to chronic renal allograft nephropathy. As a…
2017 American Transplant Congress
Outcome of Living Donor Transplantation in Pediatric Recipients Over the Last Three Decades by Era: An Analysis of UNOS Database.
V. Whittaker, M. Laftavi, Z. Acun, R. Gruessner, A. Gruessner.
Surgery, State University New York, Syracuse, NY
Background: Living donor is the potential solution to organ shortage. This retrospective analysis of UNOS database evaluates the outcome of living donor transplantation across 4…
2017 American Transplant Congress
Postoperative Serum Lactate Dehydrogenase Is a "Troponin-Like" Marker of Renal Transplant Distress.
R. Steiner, J. Halldorson.
UCSD Center for Transplantation, University of California at San Diego, San Diego, CA
Lactate dehydrogenase (LDH) is plentiful in renal tubular cells and is released during tubular injury or death. It increases for several days to 1500-2000 U/L…
2017 American Transplant Congress
Longer Anastomotic Time Leads to Delayed Graft Function.
M. Heer,^1,2 P. Trevillian,^1,2,3 A. Hibberd.^1,2,3
¹Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; ²Newcastle University, Newcastle, NSW, Australia; ³Hunter Transplant Research Foundation, Hunter Medical Research Institute, Newcastle, NSW, Australia
Background: Delayed graft function (DGF) occurs at variable rates in renal transplant recipients. It can be deleterious to renal allograft in long term. Various factors…
2017 American Transplant Congress
Longer Ischemic Time Is Associated with Late Graft Dysfunction in Pediatric Heart Transplant Recipients.
L. Schroeder,¹ S. Chowdhury,¹ A. Burnette,¹ H. Baker,¹ A. Savage,¹ A. Atz,¹ R. Butts.²
¹Medical University of South Carolina, Charleston, SC; ²UT Southwestern, Dallas, TX
Introduction: The purpose of this study was to investigate associations between clinical factors and cardiac function as measured by pressure-volume loops (PVL) in a pediatric…
2017 American Transplant Congress
Post-Transplant Graft Function Is Associated with Major Cardiovascular Events in Kidney Transplant Recipients: A Multicenter Cohort Study.
J. Park,¹ Y. Kim,² S. Yang,³ S. Park,² S.-K. Park,⁴ D. Han,⁵ Y. Kim,² Y. Kim,⁵ J. Lee.⁶
¹Department of Internal Medicine, Dongguk University Ilsan Hospital, Gyeonggi-do, Korea; ²Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; ⁴Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁵Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁶Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea
Background: Reduced kidney function is an independent risk factor for cardiovascular disease in the general population. However, the association between post-transplantation graft function and subsequent…