2017 American Transplant Congress
Pre-Transplant Recipient Transcriptomic Profile May Predict Delayed Graft Function (DGF) in Kidney Transplantation.
Background: DGF is associated with a reduced long-term graft survival. Ischemia-reperfusion damage and donors' features have been always considered as key pathogenic factors in this…2017 American Transplant Congress
Binding of Antigens by Its Specific Antibodies Results in Exosome Formation Leading to Rejection of Syngeneic Murine Cardiac Grafts.
Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix
Background: Antibody binding to its antigen can activate complement cascades leading to cell death. In addition, it can activate intracellular signals leading to rejection of…2017 American Transplant Congress
Belatacept Conversion in Kidney Recipients with Low GFR Does Not Improve Renal Function.
1Transplant, Mayo Clinic, Scottsdale, AZ; 2Biostatistics and Informatics, Mayo Clinic, Rochester, MN
Background:Belatacept interferes with signal 2 of T cell activation via blockade CD80/86 which doesn't adversely impact renal function. We tested a hypothesis that Belatacept conversion…2017 American Transplant Congress
The Incidence and Outcomes of Fever of Unknown Origin After Pancreas Transplantation.
1Houston Methodist Hospital, Houston, TX; 2Veloxis Pharmaceuticals, Cary, NC
Previous studies have shown that approximately 20% of febrile episodes in transplant recipients are not associated with infection. At our center, fever of unknown origin…2017 American Transplant Congress
Transcatheter Relief of Symptomatic Hepatic Venous Outflow Obstruction Following Pediatric Liver Transplantation.
Cincinnati Children's Hospital, Cincinnati, OH
Background: Technical-variant allograft (TVA) pediatric liver transplantation (LT) is associated with vascular complications. Early recognition and treatment of hepatic venous outflow obstruction (HVOO) may be…2017 American Transplant Congress
The Polymer Pro-Drug APP-103 Mitigates I/R Injury and Improves Graft Function in a Pre-Clinical Renal Transplant Model.
Purpose: Ischemia-reperfusion injury (IRI) is the strongest non-HLA factor that augments allogenicity of transplanted organs. Damage subsequent to IRI is critically linked to an abundance…2017 American Transplant Congress
Improved Outcomes After Liver Transplantation from Controlled DCD Donors with Normothermic Regional Perfusion.
Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
Background: Normothermic regional perfusion (NRP) is currently explored as a method to recover organs from Maastricht category I-III Donors after circulatory death (DCD). This study…2017 American Transplant Congress
Laparoscopic Sleeve Gastrectomy Improves Renal Transplant Candidacy and Posttransplant Outcomes in Morbidly Obese Patients.
Surgery, University of Cincinnati, Cincinnati, OH
BACKGROUND: Morbid obesity remains a barrier to kidney transplantation (KT) and is associated with increased delayed graft function (DGF), graft loss, and wound complications. Laparoscopic…2017 American Transplant Congress
Impact of STEEN vs Gelofusine as Perfusate During Normothermic Ex Vivo liver Perfusion on Outcome of Pig Liver Transplantation.
Multiorgan Transplant Program, Toronto General Hospital, Toronto, ON, Canada
European and North American clinical trials have used two different perfusate solutions for normothermic ex vivo liver perfusion (NEVLP): Gelofusine (bovine derived gelatin-based solution) and…2017 American Transplant Congress
Kidney Insertion Through Vagina and Robotic Assisted Laparoscopic Kidney Transplantation: A Pilot Study.
Minimally invasive kidney transplantation is emerging modality of treatment; both laparoscopic and robotic assisted laparoscopic kidney transplantation are technically feasible and safe. In female recipients,…
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