ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2017 American Transplant Congress

    Delayed Graft Function[mdash]Less Ominous for ARF or DCD Recipients?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    Delayed Graft Function (DGF) is both a transplant outcome and risk factor for graft failure. Kidneys from donors with kidney injury--such as acute renal failure…
  • 2017 American Transplant Congress

    The Incidence and Outcomes of Fever of Unknown Origin After Pancreas Transplantation.

    R. Klasek,1 S. Kuten,1 S. Patel,1,3 D. Nguyen,1 E. Graviss,1 A. Gaber,1 R. Knight.1

    1Houston Methodist Hospital, Houston, TX; 2Veloxis Pharmaceuticals, Cary, NC

    Previous studies have shown that approximately 20% of febrile episodes in transplant recipients are not associated with infection. At our center, fever of unknown origin…
  • 2017 American Transplant Congress

    Transcatheter Relief of Symptomatic Hepatic Venous Outflow Obstruction Following Pediatric Liver Transplantation.

    B. Goldstein, G. Tiao, M. Alonso, N. Johnson, J. Heubi, K. Averin, J. Bucuvalas.

    Cincinnati Children's Hospital, Cincinnati, OH

    Background: Technical-variant allograft (TVA) pediatric liver transplantation (LT) is associated with vascular complications. Early recognition and treatment of hepatic venous outflow obstruction (HVOO) may be…
  • 2017 American Transplant Congress

    The Polymer Pro-Drug APP-103 Mitigates I/R Injury and Improves Graft Function in a Pre-Clinical Renal Transplant Model.

    K. Minami,1,3 H. Uehara,1 A. Elkhal,1 S. Bae,3 J. Reder,2 B. Houser,2 P. Kang,3 S. Tullius.1

    1Transplant Surgery Division, Brigham and Women's Hospital, Boston, MA; 2Celdara Medical, LLC, Lebanon, NH; 3Beth Israel Deaconess Medical Center, Boston, MA

    Purpose: Ischemia-reperfusion injury (IRI) is the strongest non-HLA factor that augments allogenicity of transplanted organs. Damage subsequent to IRI is critically linked to an abundance…
  • 2017 American Transplant Congress

    Binding of Antigens by Its Specific Antibodies Results in Exosome Formation Leading to Rejection of Syngeneic Murine Cardiac Grafts.

    M. Sharma, W. Liu, M. Gunasekaran, S. Bansal, T. Mohanakumar.

    Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix

    Background: Antibody binding to its antigen can activate complement cascades leading to cell death. In addition, it can activate intracellular signals leading to rejection of…
  • 2017 American Transplant Congress

    Belatacept Conversion in Kidney Recipients with Low GFR Does Not Improve Renal Function.

    D. Abdelwahab,1 S. Byron,2 B. Kaplan,1 R. Heilman.1

    1Transplant, Mayo Clinic, Scottsdale, AZ; 2Biostatistics and Informatics, Mayo Clinic, Rochester, MN

    Background:Belatacept interferes with signal 2 of T cell activation via blockade CD80/86 which doesn't adversely impact renal function. We tested a hypothesis that Belatacept conversion…
  • 2017 American Transplant Congress

    Impact of STEEN vs Gelofusine as Perfusate During Normothermic Ex Vivo liver Perfusion on Outcome of Pig Liver Transplantation.

    I. Linares, D. Kollmann, J. Echeverri, M. Kaths, R. Rosales, C. Bruguera, M. Hamar, P. Urbanellis, S. Ganesh, N. Selzner, M. Selzner.

    Multiorgan Transplant Program, Toronto General Hospital, Toronto, ON, Canada

    European and North American clinical trials have used two different perfusate solutions for normothermic ex vivo liver perfusion (NEVLP): Gelofusine (bovine derived gelatin-based solution) and…
  • 2017 American Transplant Congress

    Kidney Insertion Through Vagina and Robotic Assisted Laparoscopic Kidney Transplantation: A Pilot Study.

    P. Modi,1 B. Pal,1 S. Kumar,1 R. Nagarajan,1 V. Kothari,1 M. Modi,2 V. Shah,2 V. Kute,3 H. Patel,3 H. Trivedi.3

    1Transplantation Surgery and Urology, Institute of Kidney Diseases and Research Centre, Ahmedabad, India; 2Anesthesiology, Institute of Kidney Diseases and Research Centre, Ahmedabad, India; 3Nephrology, Institute of Kidney Diseases and Research Centre, Ahmedabad, India

    Minimally invasive kidney transplantation is emerging modality of treatment; both laparoscopic and robotic assisted laparoscopic kidney transplantation are technically feasible and safe. In female recipients,…
  • 2017 American Transplant Congress

    Everolimus Does Not Increase Risk of Delayed Graft Function or Prolong Duration of Dialysis in Renal Transplantation.

    F. Shihab,1 Y. Qazi,2 S. Mulgaonkar,3 K. McCague,4 D. Patel,4 V. Peddi,5 D. Shaffer.6

    1Univ of Utah, Salt Lake City; 2Univ of Southern California, Los Angeles; 3Barnabas Health, West Orange; 4Novartis, East Hanover; 5California Pacific Medical Center, San Francisco; 6Vanderbilt Univ Medical Center, Nashville

    US92 (NCT01025817) is a phase III, 12 month, open-label, randomized study comparing everolimus (EVR) plus low-dose tacrolimus (LTac) vs. mycophenolate mofetil (MMF) with standard-dose tacrolimus…
  • 2017 American Transplant Congress

    Improved Outcomes After Liver Transplantation from Controlled DCD Donors with Normothermic Regional Perfusion.

    G. Oniscu, F. Hunt, W. Herries, I. Currie, A. Sutherland, C. Beattie, E. Thomson.

    Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

    Background: Normothermic regional perfusion (NRP) is currently explored as a method to recover organs from Maastricht category I-III Donors after circulatory death (DCD). This study…
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