Articles tagged "Graft function"

2018 American Transplant Congress
High Serum Resistin Levels Predict Future Acute Kidney Injury in Kidney Transplantation Patients
M-.C. Lee,^1,3 B-.G. Hsu.^2,3
¹Surgery, Tzu Chi General Hospital, Hualien, Taiwan; ²Nephrology, Tzu Chi General Hospital, Hualien, Taiwan; ³School of Medicine, Tzu Chi University, Hualien, Taiwan.
Introduction:Resistin has a pathogenic role in the development and progression of atherosclerosis. This study was evaluated the association between serum resistin levels and future acute…
2018 American Transplant Congress
Intravenous Immunoglobulins and Methylprednisolone Stabilizes Renal Allograft Function in the Majority of Patients with C-aABMR
K. Sablik, M. Clahsen-van Groningen, C. Looman, J. Damman, M. van Agteren, M. Betjes.
Erasmus Medical Center, Rotterdam, Netherlands.
BackgroundChronic active antibody mediated rejection (c-aABMR) leads to progressive decline in allograft function and is a major contributor to long-term kidney allograft loss. To date,…
2018 American Transplant Congress
Differences in Preservation Solution Formulas and Its Effects on Early Graft Function
J. Brooks, P. Wiederhold, K. Jiles, A. Chiodo Ortiz, M. Dewey, M. Bailey, N. Koizumi, E. Rady, J. Ortiz.
University of Toledo Medical Center, Toledo, OH; University of California-Los Angeles, Los Angeles, CA; Life Connection of Ohio, Maumee, OH; George Mason University, Fairfax, VA.
Introduction: Machine perfusion has proven benefits and is common practice among transplant centers. However, the formulas of preservation solutions vary between organ procurement organizations (OPOs).…
2018 American Transplant Congress
HO-1 Regulates SIRT1– Autophagy Pathway in Liver Transplantation: From Mouse-to-Human
K. Nakamura,¹ S. Kageyama,¹ S. Yue,¹ A. Aziz,¹ T. Ito,¹ D. Oncel,¹ B. Ke,¹ R. Sosa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Division of Liver Transplantation, UCLA, Los Angeles, CA; ²Pathology and Laboratory Medicine, UCLA, Los Angeles, CA.
Liver ischemia-reperfusion injury (IRI) represents a major risk factor for early graft dysfunction and a key obstacle to expanding the donor pool in orthotopic liver…
2018 American Transplant Congress
SGLT2 Inhibition in Kidney Transplant Recipients with Diabetes
M. Guthoff,¹ M. Mahling,¹ S. Nadalin,² N. Heyne.¹
¹Dept. of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany; ²Dept. of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany.
Purpose: Sodium-glucose cotransporter 2 (SGLT2) inhibition has been shown to reduce cardiovascular mortality and preserve kidney function in patients with type 2 diabetes. Kidney transplant…
2018 American Transplant Congress
Impact of Pulsatile Perfusion Machine on Postoperative Outcomes in Standard Criteria Donor Kidney Transplants
S. Costa,^1,2 T. Sandes-Freitas,^1,2 P. Fernandes,² R. Esmeraldo.¹
¹Hospital Geral de Fortaleza, Fortaleza, Brazil; ²Universidade Federal do Ceara, Fortaleza, Brazil.
Introduction: Delayed graft function (DGF) negatively impacts kidney transplant (KT) outcomes. Our aim was to assess the impact of pulsatile machine perfusion (MP) on KT…
2018 American Transplant Congress
The Impact of Pre-Operative Opioid Use on Delayed Graft Function in Adult Kidney Transplant Recipients
N. Patel, B. O'Brien, D. Taber, N. Pilch, P. Baliga, Z. Elmaasarani, S. Ball, P. Mauldin, L. Wilson, R. Gilbert, J. Fleming.
MUSC, Charleston, SC.
Background and Objectives: Opioid use is associated with AKI and ATN through both direct and indirect mechanisms, including alterations in the autonomic nervous system, the…
2018 American Transplant Congress
Expression of the Senescence Marker P16/INK4A in Kidney Implantation Biopsies is Uniquely Associated with Poor Late Graft Function
K. Famulski, P. Halloran.
University of Alberta, Edmonton, Canada.
With the aging donor population, accurate assessment of tissue quality of deceased donor kidneys is required to determine the intermediate and long term graft performance,…
2018 American Transplant Congress
Impact of Total Graft Steatotic Mass in Liver Transplant Outcomes
L. De Gregorio,¹ E. Bugeaud,¹ G. Galliano,² H. Bohorquez,¹ D. Bruce,¹ I. Carmody,¹ A. Cohen,¹ J. Seal,¹ D. Sonnier,¹ A. Mathur,¹ G. Loss.¹
¹Abdominal Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; ²Pathology, Ochsner Clinic Foundation, New Orleans, LA.
INTRODUCTIONGraft steatosis is a risk factor for early allograft dysfunction (EAD) and is thought to portend inferior transplant outcomes. The impact of total steatosis, combining…
2018 American Transplant Congress
A Machine Learning Approach for Prediction of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients
S. Kawakita,¹ A. Waterman,^1,2 M. Everly.¹
¹Terasaki Research Institute, Los Angeles, CA; ²Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Introduction:Delayed graft function (DGF) is an early signal of graft injury that is common in deceased donor kidney transplant (DDKT) recipients. Although we have predictive…