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Articles tagged "Graft function"

  • 2019 American Transplant Congress

    Outcome of Renal Transplantation in Systemic Amyloidosis

    S. Law1, L. Helen2, T. Resk2, A. Wechalekar2, J. Gillmore2, R. Motallebzadeh1

    1Renal Medicine, Royal Free Hospital, London, United Kingdom, 2UCL Division of Medicine, National Amyloidosis Centre, London, United Kingdom

    *Purpose: Systemic amyloidosis accounts for approximately 0.8% of end stage renal disease (ESRD) in the UK. Outcomes following renal transplantation in systemic amyloidosis were historically…
  • 2019 American Transplant Congress

    Daily Use of a Muscle Pump Activator Device Reduces Hospitalization and Improves Graft Function Post Transplantation: A Randomized Controlled Trial

    W. Xie, S. Aquil, K. Pacoli, R. Al-Ogaili, P. Luke, A. Sener

    London Health Sciences Center, London, Ontario, Canada, London, ON, Canada

    *Purpose: Kidney and simultaneous pancreas-kidney (SPK) transplant recipients can have prolonged post-operative hospitalization due to edema, delayed mobilization, and delayed graft function. Traditionally, TED stockings…
  • 2019 American Transplant Congress

    Contrast-Enhanced Ultrasonography Predicts Insulin Secretion Ability at 1 Year after Pancreas Transplantation

    N. Aida1, T. Kenmochi1, T. Ito1, K. Kurihara1, A. Kawai1, T. Nishikawa2, I. Hiratsuka3, M. Shibata3, A. Suzuki3, M. Hasegawa4, M. Kusaka5, M. Hoshinaga5

    1Transplantation and Regenerative Medicine, Fujita Health University, Toyoake, Japan, 2Liver, Biliary Tract and Pancreas Diseases, Fujita Health University, Toyoake, Japan, 3Endocrinology and Metabolism, Fujita Health University, Toyoake, Japan, 4Nephrology, Fujita Health University, Toyoake, Japan, 5Urology, Fujita Health University, Toyoake, Japan

    *Purpose: We have previously reported that contrast enhanced ultrasonography (CEUS) is useful to evaluate the graft circulation and to predict the endocrine function of the…
  • 2018 American Transplant Congress

    SIRT1-Ikaros Axis Promotes Macrophage M2 Polarization and Protects Liver Graft from Ischemia-Reperfusion Injury

    K. Nakamura,1 S. Kageyama,1 X. Li,2 A. Aziz,1 R. Sosa,3 E. Reed,3 F. Kaldas,1 R. Busuttil,1 J. Kupiec-Weglinski.1

    1Surgery, Liver Transplant, UCLA, Los Angeles, CA; 2NIEHS, Durham, NC; 3Pathology, UCLA, Los Angeles, CA.

    Although pre-clinical studies have reported the efficacy of Sirtuin 1 (SIRT1) to protect livers from ischemia-reperfusion injury, its clinical relevance in liver transplantation (LT) has…
  • 2018 American Transplant Congress

    Urinary Chemokine CXCL-10 in Long Term Renal Transplant Patients Associates with Urinary Tract Infections and Microvascular Damage

    G. Irish,1,2 M. Hockley,1,2 S. Kireta,1,2 J. Johnson,1,2 R. Carroll.1,2

    1Central and Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia; 2The Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

    Non-invasive biomarkers are needed to predict rejection post kidney transplantation. In the early transplant period, urinary CXCL-9 and CXCL-10 associate with rejection. We assessed the…
  • 2018 American Transplant Congress

    Inter-Correlations between Psycho-Social Pre-Transplant Determinants of Post-Transplant Kidney Allograft Function

    S. Shah, A. Gamilla-Crudo, B. Schreiber, C. Machner, O. Aleter, M. Mujtaba.

    Transplant Services, UTMB, Galveston, TX.

    Psycho-social factors are common in patients with advanced and end stage kidney disease and they may be associated with post kidney transplant outcomes. The aim…
  • 2018 American Transplant Congress

    β-Glucuronidase Gene Expression in Stool Samples Associated with Chronic Allograft Dysfunction in Kidney Transplants

    A. Israni,1,2 D. Knights,3 G. Al-Ghalith,3 A. Muthusamy,2 B. Wu,4 W. Oetting,5 D. Schaldt,2 R. Remmel,5 P. Jacobson,5 For DeKAF Genomics & GEN03 Investigators.1

    1Medicine, HCMC, University of MN (UMN), Minneapolis; 2Minneapolis Medical Research Foundation (MMRF), Mpls; 3Computer Science, UMN, Mpls; 4Biostatistics, UMN, Mpls; 5College of Pharmacy, UMN, Mpls.

    Background: Myocophenolate mofetil (MMF) is a prodrug that is extensively and rapidly converted to the active component, mycophenolic acid (MPA). MPA undergoes extensive enterohepatic recycling…
  • 2018 American Transplant Congress

    Kidney Transplantation (KTx) Using Kidneys from Deceased Donors (DD) with AKIN Stage 2 and 3 Are Associated with Excellent Graft Outcomes

    A. Kumar, K. Reddy, A. Srinivasan, J. Huskey, H. Khamash, M. Smith, A. Moss, R. Heilman.

    Mayo Clinic, Phoenix.

    BackgroundKTx from DD with AKI can be a good source of kidneys however these kidneys are underutilized. The aim of this study is to determine…
  • 2018 American Transplant Congress

    Direct-Acting Antiviral Therapy Immune-Mediated Graft Dysfunction in Liver Transplant Recipients with Hepatitis C

    C. Chan,1 E. Agudelo,2 J. Haydek,3 M. Hoteit,4 M. Laurito,5 J. Norvell,3 T. Schiano,6 N. Terrault,2 E. Verna,5 A. Yang,1 J. Levitsky.1

    1Northwestern University, Chicago, IL; 2UCSF, San Francisco, CA; 3Emory University, Atl, GA; 4University of Pennsylvania, Philadelphia, PA; 5Columbia University, NY, NY; 6Mount Sinai, NY, NY.

    Background and Aims:Interferon (IFN) treatment of hepatitis C virus (HCV) infection after liver transplantation (LT) can result in severe immune-mediated graft dysfunction (IGD). The occurrence…
  • 2018 American Transplant Congress

    Do Protocol Biopsies in the Highly Sensitized Improve Renal Allograft Survival? A Single Center Evaluation of 2 Year Graft Function

    S. Kuppachi, R. Kalil, M. Fraer, M. Sanders, M. Swee, Z. Stewart, C. Thomas.

    Organ Transplant Center, University of Iowa, Iowa City, IA.

    Highly sensitized kidney transplant recipients (hsKTR) are at an increased risk of antibody mediated rejection (AMR). Following implementation of the new kidney allocation system (KAS)…
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