Articles tagged "Graft function"

2020 American Transplant Congress
Prophylactic Treatment with Antioxidant Nanoparticles Attenuate Ischemia/Reperfusion Injury in BALB/c Mice
S. Yoon¹, K. Lee¹, W. Hwang¹, S. Yun¹, K. Yoon²
¹Nephrology, Konyang University Hospital, Daejeon, Korea, Republic of, ²Chemistry, Hannam University, Daejeon, Korea, Republic of
*Purpose: Kidney is more susceptible to hypoxic damage than other organ because kidney tissue consumes most of oxygen to move various solute across membrane. Ischemia/reperfusion…
2020 American Transplant Congress
Kidney Transplantation and Short Bowel Syndrome: Outcomes and Challenges
E. Abou Diwan¹, A. Patel², N. Elias³, K. Safa³
¹American University of Beirut, Beirut, Lebanon, ²Nephrology, Brigham and Women's Hospital, Boston, MA, ³Transplant Center, Massachusetts General Hospital, Boston, MA
*Purpose: Among patients with short bowel syndrome (SBS), kidney disease is highly prevalent due to volume depletion, crystal nephropathies, and many other reasons. Kidney transplantation…
2020 American Transplant Congress
Male Native Hawaiians and Pacific Islanders are at Risk for Delayed Graft Function after Renal Transplantation
L. Lee¹, K. Bozhilov², L. L. Wong²
¹The Queen's Transplant Center, Honolulu, HI, ²Surgery, University of Hawaii - John A. Burns School of Medicine, Honolulu, HI
*Purpose: Native Hawaiians and Pacific Islanders (NHPI) have an increased risk of chronic kidney disease with disproportionately fewer patients receiving kidney transplants; this study aims…
2020 American Transplant Congress
Donor Kidney Perfusion Fluid Extracellular Vesicles as Markers of Graft Function
A. K. Rutman, S. Negi, N. Saberi, J. Tchervenkov, S. Paraskevas
Research Institute of the McGill University Health Institute, Montreal, QC, Canada
*Purpose: Kidney transplantation is a life-saving treatment for many patients with end-stage renal failure. Recently, machine perfusion of kidneys prior to transplantation has emerged as…
2020 American Transplant Congress
Rabbit Anti-Thymocyte Globulin versus Anti-T Lymphocyte Globulin Rescue Therapies in Delayed Graft Function after Kidney Transplantation from Donors after Cardiac Death
H. Yang¹, Y. Shi², X. Li¹, C. Long¹, H. Li³, Z. Wang³
¹Department of Organ Transplantation, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China, ²Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ³Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Delayed graft function (DGF) is common in recipients of kidney transplants from donation after cardiac death (DCD) donors, induction therapy with monoclonal or polyclonal…
2020 American Transplant Congress
Estrogen Receptor Beta Deletion in the Vascular Endothelium is Protective in Renal Ischemia Reperfusion Injury
L. Krumeich¹, P. Hernandez¹, C. O'Brien¹, S. Concors¹, Z. Wang¹, G. Ge¹, W. Hancock², M. Levine¹
¹Hospital of University of Pennsylvania, Philadelphia, PA, ²Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to early allograft dysfunction (EAD) in kidney transplantation. We previously identified lower rates of EAD…
2020 American Transplant Congress
Pattern of Renal Allograft Injury in Recipients with Normal Donor-Derived Cell-Free DNA
W. Xie, N. Goussous, A. Haririan, M. Weir, J. Bromberg
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a novel non-invasive test currently used as a biomarker for identification of transplant rejection or injury. Here, we sought…
2020 American Transplant Congress
The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function
S. Costa¹, F. Barroso¹, C. Oliveira¹, E. Daher¹, P. Fernandes¹, L. Andrade², R. Esmeraldo³, T. Sandes-Freitas¹
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, ³Hospital Geral de Fortaleza, Fortaleza, Brazil
*Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
2020 American Transplant Congress
Improving Evaluation and Follow-Up of Living Kidney Donors: Role of Radioisotopic Glomerular Filtration Rate and Renal Functional Reserve
V. Cantaluppi¹, G. Guglielmetti¹, U. M. Morosini¹, A. Nappo¹, G. Merlotti¹, A. Airoldi¹, M. Quaglia¹, C. Ronco²
¹Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy, ²Nephrology, Dialysis and Kidney Transplantation Unit, University of Padova, Vicenza, Italy
*Purpose: After donation, living kidney donors (KD) develop an early and transient loss of kidney function (KF), defined as Acute Kidney Injury (AKI). Its recovery…
2020 American Transplant Congress
Gross Morphological Score for Deceased Donor Kidneys Can Predict Delayed Graft Function in Kidney Transplant Recipients
M. Mandurah, M. A. Levine, A. Sener, P. Luke
Department of Kidney Transplantation, London Health Sciences Center, London, ON, Canada
*Purpose: Both microscopy and kidney donor profile index (KDPI) scoring systems have been used to predict kidney transplant outcomes. Utilizing gross renal morphology, we designed…