2021 American Transplant Congress
A Pediatric Liver Allograft with an Occult Urea Cycle Defect Carrier Mutation Causing Delayed Graft Function and Metabolic Crisis After Liver Transplantation
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: We report an interesting case of delayed graft function following pediatric liver transplantation, which was attributed to previously unrecognized urea cycle carrier genetic defect…2021 American Transplant Congress
Do Pretransplant C-peptide Levels Influence Outcomes in Simultaneous Pancreas-Kidney Transplantation? A Matched Case-Control Study
Abdominal Transplant Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Experience with simultaneous pancreas-kidney transplant (SPKT) in uremic patients (pts) with detectable pretransplant C-peptide (Cp) levels and a “type 2” diabetes mellitus (DM) phenotype…2021 American Transplant Congress
Myeloid Yap Signaling is Required for Hepatic Cytoprotection in Liver Ischemia-reperfusion Injury
*Purpose: Liver ischemia-reperfusion injury (IRI) is recognized as an innate immunity-driven local inflammation response during hemorrhagic shock, liver resection and transplantation. Yes-associate protein 1 (YAP)…2021 American Transplant Congress
Prolonged Cold Ischemic Time Demonstrating Minor Effect on Outcomes Following Renal Transplantation – A Paired Kidney Analysis
1Columbia University Irving Medical Center, New York, NY, 2Columbia University, New York, NY
*Purpose: An improved understanding of the effects of cold ischemia time (CIT) on deceased donor kidney (DDK) outcomes may increase organ utilization by clarifying the…2021 American Transplant Congress
Dual Lactate Clearance in the Liver Viability Assessment During Normothermic Machine Perfusion
*Purpose: Liver normothermic machine perfusion (NMP) has been increasingly performed as a tool of organ preservation and to evaluate donor function. The perfusate lactate clearance…2021 American Transplant Congress
Predicting Post-transplant Death and Graft Loss Risk: Insight at Listing
1CareDx, Brisbane, CA, 2Saint Louis University, St. Louis, MO
*Purpose: Prognostication models for post-transplant outcomes deriving inputs from information collected on donor (DDR/LDR), candidate (TCR) and transplant recipient (TRR) registrations can provide useful information…2021 American Transplant Congress
Efficacy of Ex Vivo Normothermic Limb Perfusion in Maintaining Cellular Viability and Muscle Function
*Purpose: The purpose of this study was to evaluate cellular injury and myocyte function of amputated limbs following ex vivo normothermic limb perfusion (EVNLP) compared…2021 American Transplant Congress
Role of Serial Donor Derived Cell-Free DNA Monitoring in Kidney Transplant Recipients
Nephrology, Stanford University School of Medicine, Palo Alto, CA
*Purpose: Donor derived cell-free DNA (dd cf-DNA; Allosure, CareDx) is increasingly employed for non-invasive kidney transplant monitoring. The goal of this study was 1) to…2021 American Transplant Congress
Dynamic Forecasting of Patient-Specific Kidney Transplant Function with a Sequence-to-Sequence Deep-Learning Model
*Purpose: Alike other clinical biomarkers, eGFR trajectories are characterized by intra-individual variability, related to biological fluctuations and analytical error. These fluctuations hamper the distinction between…2021 American Transplant Congress
Donor-derived Cell-free DNA Distinguishes Acute Rejection from Other Causes of Graft Injury in Liver Transplant Recipients
*Purpose: The donor derived cell-free DNA (ddcfDNA) has emerged as strong biomarker for allograft injury, where the fraction of ddcfDNA is reported to increase in…
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