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Articles tagged "Graft failure"

  • 2017 American Transplant Congress

    α-Lipoc Acid Improve the Short Term Outcomes in Human Liver Transplantation.

    P. Casciato,1 N. Ambrosi,2 C. Fiorella,2 M. Vasquez,1 A. Gadano,1 M. de Santibañes,1 E. de Santibañes,1 M. Zandomeni,1 M. Chahdi,1 J. Laquinandi,1 P. Santofimia Castaño,3 J. Iovanna,3 E. Chuluyan,2 C. Incardona.4

    1Liver Transplantation Unit, Hospital Italiano, Buenos Aires, Argentina; 2CEFYBO, UBA-CONICET, Facultad de Medicina, Buenos Aires, Argentina; 3INSERM, Center of Research in Cancerology of Marseille (CRCM), Marseille, France; 4Fundación GADOR, GADOR, Buenos Aires, Argentina

    In liver transplantation (LT) the postreperfusion syndrome (PRS) is a serious intraoperative complication. The effect of α-lipoic acid (ALA) has not been evaluated. A double…
  • 2017 American Transplant Congress

    Variables Associated with Liver Graft Utilization and 30-Day Failure: A Liver Graft Quality Index.

    J. Tang,1 M. Esfandiari,1 A. Zarrinpar.2

    1Statistics, University of California, Los Angeles, CA; 2Surgery, University of California, Los Angeles, CA

    The quantitative evaluation of liver graft quality remains one of the most understudied clinical problems in transplantation. A few scoring systems have been proposed, but…
  • 2017 American Transplant Congress

    25-Hydroxyvitamin D [25(OH)D], but Not 1,25-Dihydroxyvitamin D [1,25(OH)2D], Independently Predicts Kidney Graft Failure: The Wisconsin Allograft Recipient Database (WisARD).

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    Vitamin D deficiency is common in chronic kidney disease and is associated with cardiovascular events and mortality. Kidney transplant recipients are at elevated risk of…
  • 2017 American Transplant Congress

    Impact of Peri-Transplant Viral Upper Respiratory Infection on Pediatric Liver Transplant Outcomes.

    J. Kohler,1 T. Miloh,1 K. Hosek,1 J. Goss,2 F. Munoz.1

    1Pediatrics, Baylor College of Medicine, Houston, TX; 2Surgery, Texas Children's Hospital, Houston, TX

    BACKGROUND: Viral upper respiratory infection (vURI) is common in children and its effect at the time of liver transplant (LT) on the post-operative outcomes is…
  • 2017 American Transplant Congress

    Impact of Alemtuzumab Induction on Hepatitis C Treatment Outcomes Post-Renal Transplantation.

    S. Jonchhe, J. Husson, J. Casale, R. Adekunle, P. Mathur, J. Gripshover, B. Ravichandran.

    University of Maryland Medical Center, Baltimore, MD

    BackgroundDirect-acting antiviral agents (DAAs) have improved treatment outcomes for Hepatitis C virus (HCV). Given high rates of treatment success with few side effects, eradication of…
  • 2017 American Transplant Congress

    Vimentin Regulates ß-Catenin Translocation During Epithelial to Mesenchymal Transition in Renal Fibrosis.

    R. Lopez-Soler, Z. Wang, A. Divanyan.

    Sugery, Section of Transplantation, Albany Medical Center, Albany, NY

    Introduction: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    A Thirteen-Year Mayo Clinic Retrospective Study of the Syndrome of Rapid Onset ESRD Among Renal Transplant Recipients, 2001-2013.

    M. Onuigbo,1,2 N. Agbasi.3

    1Medicine, Mayo Clinic, Rochester, MN; 2Nephrology, Mayo Clinic Health System, Eau Claire, WI; 3Mental Health, North East London NHS Foundation Trust, Ilford, Essex, United Kingdom

    Introduction: We described the syndrome of rapid onset ESRD (SORO-ESRD), acute yet irreversible renal failure, for the first time in the journal Renal Failure in…
  • 2017 American Transplant Congress

    Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Non-Human Primates: The Immunomodulatory Effect of Donor Bone Marrow Transplantation Does Not Prevent the Development of Chronic Rejection in the Absence of Durable Mixed Chimerism.

    Z. Ng, A. Lellouch, A.-R. Gama, I. Schol, I. Rosales, R. Colvin, L. Geoghegan, J. Kurtz, C. Cetrulo.

    Massachusetts General Hospital, Boston, MA

    PURPOSE: Donor bone marrow transplantation (DBMT) has been investigated in experimental and clinical vascularized composite allotransplantation (VCA). With longer-term follow-up, reports of chronic VCA rejection…
  • 2017 American Transplant Congress

    Procurement Kidney Biopsy versus KDRI for Predicting Graft Survival.

    I. Hall,1 C. Parikh,2 B. Schröppel,3 F. Weng,4 Y. Jia,2 H. Thiessen-Philbrook,2 P. Reese,5 M. Doshi.6

    1University of Utah, Salt Lake City, UT; 2Yale University, New Haven, CT; 3University Hospital, Ulm, Germany; 4Saint Barnabas Medical Center, Livingston, NJ; 5University of Pennsylvania, Philadelphia, PA; 6Wayne State University, Detroit, MI

    Background: The kidney donor risk index (KDRI) incorporates 10 variables to match organ quality with expected recipient survival. Though controversial, procurement biopsies are often performed…
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