ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2017 American Transplant Congress

    Vimentin Regulates ß-Catenin Translocation During Epithelial to Mesenchymal Transition in Renal Fibrosis.

    R. Lopez-Soler, Z. Wang, A. Divanyan.

    Sugery, Section of Transplantation, Albany Medical Center, Albany, NY

    Introduction: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2017 American Transplant Congress

    Variables Associated with Liver Graft Utilization and 30-Day Failure: A Liver Graft Quality Index.

    J. Tang,1 M. Esfandiari,1 A. Zarrinpar.2

    1Statistics, University of California, Los Angeles, CA; 2Surgery, University of California, Los Angeles, CA

    The quantitative evaluation of liver graft quality remains one of the most understudied clinical problems in transplantation. A few scoring systems have been proposed, but…
  • 2017 American Transplant Congress

    25-Hydroxyvitamin D [25(OH)D], but Not 1,25-Dihydroxyvitamin D [1,25(OH)2D], Independently Predicts Kidney Graft Failure: The Wisconsin Allograft Recipient Database (WisARD).

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    Vitamin D deficiency is common in chronic kidney disease and is associated with cardiovascular events and mortality. Kidney transplant recipients are at elevated risk of…
  • 2017 American Transplant Congress

    Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Non-Human Primates: The Immunomodulatory Effect of Donor Bone Marrow Transplantation Does Not Prevent the Development of Chronic Rejection in the Absence of Durable Mixed Chimerism.

    Z. Ng, A. Lellouch, A.-R. Gama, I. Schol, I. Rosales, R. Colvin, L. Geoghegan, J. Kurtz, C. Cetrulo.

    Massachusetts General Hospital, Boston, MA

    PURPOSE: Donor bone marrow transplantation (DBMT) has been investigated in experimental and clinical vascularized composite allotransplantation (VCA). With longer-term follow-up, reports of chronic VCA rejection…
  • 2017 American Transplant Congress

    Procurement Kidney Biopsy versus KDRI for Predicting Graft Survival.

    I. Hall,1 C. Parikh,2 B. Schröppel,3 F. Weng,4 Y. Jia,2 H. Thiessen-Philbrook,2 P. Reese,5 M. Doshi.6

    1University of Utah, Salt Lake City, UT; 2Yale University, New Haven, CT; 3University Hospital, Ulm, Germany; 4Saint Barnabas Medical Center, Livingston, NJ; 5University of Pennsylvania, Philadelphia, PA; 6Wayne State University, Detroit, MI

    Background: The kidney donor risk index (KDRI) incorporates 10 variables to match organ quality with expected recipient survival. Though controversial, procurement biopsies are often performed…
  • 2017 American Transplant Congress

    Proteasome Modulation an Effective Strategy to Ameliorate Steatotic Liver Grafts Viability After Preservation.

    M. Zaouali,1 A. Panisello Roselló,1 T. Carbonell,2 A. Garcia-Gil,3 A. Lopez,4 R. Adam,4 J. Rosello-Catafau.1

    1Patología Experimental, Instituto de Investigaciones Biomédicas de Barcelona, CSIC, Barcelona, Spain; 2Phisiology, Fac. of Biology, Universitat de Barcelona, Barcelona, Spain; 3Transplantation, Hospital Clínico, Zaragoza, Spain; 4Hepato- Biliare Unit, Hôpital Paul Brousse, INSERM U-776, Université Paris Sud, Paris, France

    Recently we provided evidence for a possible protective role of proteasome inhibition during liver graft preservation. Although, several reported data confirmed that the proteolytic activity…
  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    A Thirteen-Year Mayo Clinic Retrospective Study of the Syndrome of Rapid Onset ESRD Among Renal Transplant Recipients, 2001-2013.

    M. Onuigbo,1,2 N. Agbasi.3

    1Medicine, Mayo Clinic, Rochester, MN; 2Nephrology, Mayo Clinic Health System, Eau Claire, WI; 3Mental Health, North East London NHS Foundation Trust, Ilford, Essex, United Kingdom

    Introduction: We described the syndrome of rapid onset ESRD (SORO-ESRD), acute yet irreversible renal failure, for the first time in the journal Renal Failure in…
  • 2017 American Transplant Congress

    Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients.

    N. Lam,1 A. Garg,2 G. Knoll,3 J. Kim,4 K. Lentine,5 E. McArthur,6 K. Naylor,6 S. Bota,6 M. Sood.3

    1University of Alberta, Edmonton, Canada; 2Western University, London, Canada; 3University of Ottawa, Ottawa, Canada; 4University of Toronto, Toronto, Canada; 5Saint Louis University School of Medicine, St. Louis; 6Institute for Clinical Evaluative Sciences, London, Canada

    Background: The incidence of venous thromboembolism (VTE) in kidney transplant recipients varies widely in the literature. The implications of VTE for morbidity and mortality in…
  • 2017 American Transplant Congress

    Delayed Graft Function[mdash]Less Ominous for ARF or DCD Recipients?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    Delayed Graft Function (DGF) is both a transplant outcome and risk factor for graft failure. Kidneys from donors with kidney injury--such as acute renal failure…
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