ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2017 American Transplant Congress

    Impact of Type of Kidney (Living vs. Deceased) on Urinary Podocyte Excretion Rate in Renal Allografts.

    A. Naik, D. Luan, D. Cibrik, M. Samaniego, K. Woodside, M. Chowdhury, S. Wang, R. Wiggins.

    U Michigan, Ann Arbor

    Aim: Long term allograft survival has not improved.Surveillance biopsy studies have demonstrated that chronic microcirculatory injury and progressive glomerulosclerosis are the most common histological finding…
  • 2017 American Transplant Congress

    Glycolytic and Glutaminolytic Metabolism Supports IL-15 Induced Inflammatory Response of Temra CD8 from Kidney Transplant Recipients.

    T.-M. Doan-Ngoc,1 G. Tilly,1 M. Yap,1 A. Caristan,1 L. Jacquemont,1 R. Danger,1 M. Cadoux,1 S. Bruneau,1 M. Giral,1 P. Guerif,1 B. Nicol,1 A. Garcia,1 D. Laplaud,1 S. Brouard,1 C. Pecqueur,2 N. Degauque.1

    1CRTI UMR1064, INSERM, Nantes, France; 2CRCNA UMR892, INSERM, Nantes, France

    Rational. We have recently shown that the accumulation of TEMRA CD8 in kidney transplant recipients (Tx) is associated with a higher risk of kidney dysfunction.…
  • 2017 American Transplant Congress

    Epigenetic Modifications in the Progression to Chronic Renal Allograft Injury.

    V. Bontha,1 D. Maluf,1 M. Dozmorov,2 K. Archer,3 L. Gallon,4 V. Mas.1

    1UVA, Charlottesville; 2VCU, Richmond; 3OSU, Columbus; 4NWU, Chicago

    Background: The renal allograft is exposed to a milieu of environmental/metabolic stimuli that trigger epigenetic modifications and thereby gene expression patterns which influence function and…
  • 2017 American Transplant Congress

    Bacteremia in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes.

    S. Brar, Y. Wang, A. Cannitelli, Y. Li, O. Famure, S. Husain, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Bloodstream infections or bacteremia is a serious complication after kidney transplantation. The incidence, risk factors, and outcomes of bacteremia among kidney transplant recipients have…
  • 2017 American Transplant Congress

    Urinary Concentration Ability in Kidney Transplant Patients as Predictor for CKD.

    P. Garcia-Garcia,1 A. Jarque,1 A. Rivero,1 A. Rodriguez,1 J. Gonzalez Posadas,1 M. Macia,1 V. Garcia Nieto,2 J. Navarro.1

    1Nephrology Service, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain; 2Pediatric Nephrology Unit, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain

    Urinary concentration is the result of a complex glomerulotubular mechanism, which culpits with the stimulation of aquaporins at the collector tubule, in response to vasopressin…
  • 2017 American Transplant Congress

    The Effect of BMI on Renal Transplant Outcomes.

    E. Giorgakis,1 K. Reddy,1 A. Singer,1 H. Khamash,2 R. Heilman.2

    1Department of Surgery, Mayo Clinic, Phoenix, AZ; 2Department of Medicine, Mayo Clinic, Phoenix, AZ

    Purpose of the study was to explore the effect of BMI class on renal transplant outcomes.Method: Single center retrospective analysis of deceased and living donor…
  • 2017 American Transplant Congress

    De Novo, Non-Donor Specific HLA Antibodies Are Associated with Inferior Allograft Outcomes After Kidney and Simultaneous Kidney-Pancreas Transplantation.

    S. Hassan,1 G. Lucisano,1 E. Santos,2 D. McKeown,3 D. Goodall,1 A. Gueret-Wardle,1 A. McLean,1 P. Brooks,2 M. Willicombe,1 D. Taube.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom; 3Blood Transfusion, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: Donor specific antibodies [DSAs] occurring after transplantation are associated with poorer outcomes. However the significance of non-donor directed HLA antibodies [ndHLAs] after transplantation in…
  • 2017 American Transplant Congress

    Is “Death with a Functioning Graft (DWF)” Really Death with Function? Data from the Long-Term Deterioration of Kidney Allograft Function (DeKAF) Study.

    R. Gaston,1 A. Fieberg,2 L. Hunsicker,3 D. Rush,4 R. Leduc,2 J. Connett,2 A. Matas,2 DeKaf Investigators.

    1UAB, Birmingham, AL; 2U Minnesota, Minneapolis, MN; 3U Iowa, Iowa City, IA; 4U Manitoba, Winnipeg, Canada

    To understand causes of kidney transplant (KT) failure, outcomes are often segregated into death-censored graft failure (DCGF, a proxy for immunologic injury) and DWF. To…
  • 2017 American Transplant Congress

    Predictive Value of Pre-Transplant Cross-Match Techniques on Living Donor Kidney Transplant Outcomes.

    M. Meneghini,1 E. Melilli,1 I. Revuelta,3 R. Rajalingam,2 E. Rigol,4 S. Chandran,2 F. Diekmann,3 F. Vincenti,2 J. Cruzado,1 J. Martorell,4 O. Bestard.1

    1Kidney Transplant Unit, Bellvitge University Hospital; IDIBELL, Barcelona, Spain; 2Kidney Transplant Unit, UCSF Medical Centre, SanFrancisco; 3Kidney Transplant Unit, Clinic University Hospital, Barcelona, Spain; 4Immunology Department, Clinic University Hospital, Barcelona, Spain

    Study aim: To investigate the impact of different cross-match techniques and their combination before living-donor kidney transplantation(LDKT) on main clinical outcomes.Methods: Retrospective study including 394…
  • 2017 American Transplant Congress

    Endovascular Management of Transplant Renal Artery Stenosis: A Safe and Effective Treatment.

    A. Cavalcanti,1 M. Durao,1,2 B. Santos,1,2 E. Tonato,1,2 M. Doher,2 N. Guimaraes-Souza,1,2 L. Moreira Valle,1 B. Affonso,1 F. Nasser,1 A. Pacheco-Silva.1,2

    1Nephrology, Hospital Israelita Albert Einstein, São Paulo, Brazil; 2Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil

    Background:Transplant Renal Artery Stenosis (TRAS) is a low incidence complication, but if untreated, can lead to graft failure, refractory hypertension (HT) and reduced life expectancy.…
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