Articles tagged "Graft failure"

2018 American Transplant Congress
Everolimus and the Risk of Graft Loss or Death in Kidney Transplant Recipients: A Trial-Based Linkage Study
T. Ying,^1,2 G. Wong, W. Lim, G. Russ, H. Pilmore, J. Kanellis, D. Goodman, P. Trevillian, S. Campbell, M. Suranyi, M. Mathew, R. Faull, R. Masterson, R. Walker, P. O'Connell, S. Chadban.^1,2
¹Renal Medicine, Royal Prince Alfred Hospital, Camperdown, Australia; ²Kidney Node, Charles Perkins Centre, University of Sydney, Sydney, Australia.
Background: The use of mTORIs may be associated with a reduction of cancer incidence after kidney transplantation (KT) and improved graft function compared with calcineurin-inhibitor…
2018 American Transplant Congress
Risk Factors and Sequelae of Post-KT Delirium
M. McAdams DeMarco, A. Mountford, F. Warsame, R. Berkowitz, H. Ying, C. Haugen, D. Brennan, D. Segev.
JHU, Baltimore.
Background: Delirium is the acute decline in cognitive function following a noxious insult like surgery. Previous studies in other surgical settings have identified frailty and…
2018 American Transplant Congress
Identifying the Specific Causes of Kidney Allograft Loss: A Population Based Study
C. Loheac, O. Aubert, D. VIglietti, N. Kamar, M. Delahousse, C. Lefaucheur, A. Loupy.
Paris Translational Research Center for Organ Transplantation, Paris, France.
Understanding the specific causes of kidney allograft loss is mandatory to improve the longevity of kidney allografts. However, the current literature is limited by the…
2018 American Transplant Congress
Comparison of Bortezomib in Addition to Rituximab Based Treatment of Acute Antibody Mediated Rejection in Kidney Transplantation
A. Mattiazzi,^1,2 J. Pagan,^1,2 A. Arunachalam,¹ I. De la Cruz Alcantara,¹ J. Revollo,² A. Centeno,² A. Valdes,^1,2 G. Guerra.^1,2
¹Nephrology & Hypertension, University of Miami, Miami, FL; ²Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL.
Purpose:The optimal treatment strategy of acute antibody mediated rejection (AMR) in renal allograft recipients remains undefined. The aim of our study was to compare the…
2018 American Transplant Congress
New Sensitive Markers for Early Diagnosis of Transplant Glomerulopathy in Kidney Recipients
Y-.C. Xu-Dubois, K. Louis, C. Jouanneau, D. Buob, N. Ouali, A. Hertig, E. Rondeau.
U1155, INSERM, Paris, France; Urgences Néphrologiques & Transplantation Rénale, APHP, Hôpital Tenon, Paris, France; Santé Publique, APHP, Hôpital Tenon, Paris, France; Sorbonne Universités, UPMC Université Paris 6, Paris, France.
Chronic antibody mediated rejection (ABMR) with Transplant glomerulopathy (TG) remains a major contributor of renal graft loss in the long term. New sensitive markers are…
2018 American Transplant Congress
ABO‐incompatible Deceased Donor Liver Transplantation
X. Luo, C. Haugen, A. Thomas, J. Garonzik-Wang, D. Segev.
Johns Hopkins, Baltimore, MD.
ABO-incompatible liver transplantation (ILT) has increased over the past decade despite reports suggesting that adult ILT recipient have worse outcomes than ABO-compatible liver transplant (CLT)…
2018 American Transplant Congress
Pump Resistive Index Values and Not Preimplantation Kidney Biopsy Predict Kidney Allograft Survival
J. Liu,¹ A. Blumfield,¹ M. Trivedi,¹ N. Mishra,¹ O. Mohammed,^1,2 J. Lin,³ M. Ajaimy,^1,2 J. Graham,^1,2 J. Rocca,^1,2 E. Akalin,^1,2 S. Greenstein.^1,2
¹Albert Einstein College of Medicine, Bronx, NY; ²Department of Surgery, Montefiore Medical Center, Bronx, NY; ³Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
AimTo investigate the relationship between histological findings of preimplantation kidney biopsies and pump resistive index (RI) values during machine preservation and subsequent allograft survival.MethodsWe retrospectively…
2018 American Transplant Congress
Can Immunosuppression Maintenance after Renal Allograft Failure Prevent Further Sensitization?
A. Mena-Gutierrez, K. Alquadan, A. Santos, K. Womer, M. Casey.
University of Florida, Gainesville.
After renal graft failure, retransplantation(ReTx) becomes more difficult due to sensitization to alloantigens. In 2013, our center opened a specialty clinic to maintain immunosuppression(IS) after…
2018 American Transplant Congress
Biopsy Correlates of DSA in Antibody-Mediated Rejection: C4d vs Microvascular Inflammation Scores
C. Harris, L. Anderson, R. Khaim, J. Choudhuri, R. Shapiro, S. Florman, F. Salem, M. Menon.
Icahn School of Medicine at Mount Sinai, New York, NY.
Background: The diagnosis of antibody-mediated rejection (AMR) requires the presence of both the histologic features of AMR as well as donor-specific antibodies (DSA). Whether anti-HLA…
2018 American Transplant Congress
Long-Term Success of Treatment for Cardiac Transplant AMR May Depend Upon Suppressing Class II Donor Specific Antibodies
J. Hofmann,¹ D. Weisshaar,² D. Kiprov.³
¹Dept of Medicine, California Pacific Medical Center, San Francisco, CA; ²Dept of Medicine, Kaiser Permanente, Santa Clara, CA.
Antibody mediated rejection (AMR) in cardiac transplant (tspt) patients (pts) is primarily mediated by donor specific antibodies (DSAs) and associated with reduced long-term graft survival.…