Articles tagged "Graft failure"

2019 American Transplant Congress
Predicting Allograft Outcomes of Renal Transplantation with Pretransplant Metrics
J. Tchervenkov¹, M. Nguyen², S. Negi¹, S. Paraskevas¹
¹RIMUHC, Montreal, QC, Canada, ²SSM Health Saint Louis University Hospital, St. Louis, MO
*Purpose: Early allograft dysfunction as well as long-term graft loss are major obstacles to successful kidney transplantation. Currently, kidney donor risk index (KDRI) is used…
2019 American Transplant Congress
Risk Factors for Post-Transplant Outcomes in Living and Deceased Donor Liver Transplantation. An Analysis of UNOS Registry
T. Kitajima, S. Nagai, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: The Model for End-Stage Liver Disease (MELD) score has been used for predicting waitlist outcomes in patients with cirrhosis. However, the post-transplant prognostic value…
2019 American Transplant Congress
The Association of Estimated Glomerular Filtration Rate at One Year Post-Kidney Transplant with Graft Loss is Not Modified by Delayed Graft Function
J. Gill, M. Kadatz, J. Gill
University of British Columbia, Vancouver, BC, Canada
*Purpose: In kidney transplant recipients, eGFR at 1 year post-transplant has been shown to be associated with graft loss, but it is unclear if this…
2019 American Transplant Congress
Early Allograft Dysfunction in the Setting of Histologic Ischemia Reperfusion Injury Following Liver Transplantation: Analysis of Predictors and Outcomes
T. Ito, J. Aziz, V. G. Agopian, S. Younan, J. DiNorcia, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) in Liver Transplantation (LT) is believed to contribute to Early Allograft Dysfunction (EAD). However, the relationship between IRI and EAD…
2019 American Transplant Congress
Poor Outcomes in Kidney Transplant Candidates & Recipients with History of Falls
N. Chu¹, H. Ying¹, Z. Shi¹, C. Haugen¹, S. Norman², D. Segev¹, M. McAdams-DeMarco¹
¹Johns Hopkins, Baltimore, MD, ²Michigan Medical Center, Ann Arbor, MI
*Purpose: In patients with ESRD, serious fall injuries (e.g. fractures) are associated with decreased chance of listing or transplantation. It is likely that KT candidates…
2019 American Transplant Congress
Outcomes after Simultaneous Kidney Pancreas versus Pancreas after Kidney Transplantation
S. Parajuli, A. Arunachalam, K. Swanson, F. Aziz, N. Garg, R. Redfield, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Simultaneous pancreas and kidney (SPK) or pancreas after kidney (PAK) transplant are potential options for diabetic ESRD patients. Historically, PAK pancreas graft outcomes were…
2019 American Transplant Congress
Lack of Response to Tocilizumab in Kidney Transplants with Chronic Antibody-Mediated Rejection
D. Kumar¹, F. Safavi¹, R. Sandhu¹, P. Halloran², I. Yakubu¹, M. Levy¹, I. Moinuddin¹, P. Kimball¹, L. Kamal¹, A. King¹, H. Massey¹, G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Chronic antibody mediated rejection (cAbMR) is a major cause of long-term kidney transplant (KT) loss. Traditional therapies for cAbMR have unclear efficacy with significant…
2019 American Transplant Congress
Alteration in Local Complement Activation in First 24h Post-Lung Transplantation (LTx) Helps Identify Recipients Developing Primary Graft Dysfunction
H. Kulkarni¹, M. Elvington², L. Ma¹, M. Cano¹, K. Pugh³, R. Hachem¹, J. Atkinson², A. Gelman³
¹Pulmonary and Critical Care Medicine, Washington University, Saint Louis, MO, ²Rheumatology, Washington University, Saint Louis, MO, ³Surgery, Washington University, Saint Louis, MO
*Purpose: Primary graft dysfunction (PGD) is a form of acute lung injury driven by ischemia-reperfusion mediated damage. An increase in plasma complement proteins - specifically…
2019 American Transplant Congress
Impact of Delayed Graft Function on Allograft Survival in DCD versus DBD Kidneys
T. Ishaque, A. B. Massie, J. Ruck, C. Holscher, J. G. Wang, D. L. Segev
Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Several single-center studies have suggested no link between delayed graft function (DGF) and graft survival in recipients of donation after cardiac death (DCD) kidneys,…
2019 American Transplant Congress
Early Pancreas Loss in Simultaneous Pancreas Kidney Transplants: Does It Matter for the Kidney?
D. Das, J. Huskey, R. Heilman, K. S. Reddy, A. Moss, J. Harbell, C. Jadlowiec
Mayo Clinic AZ, Phoenix, AZ
*Purpose: Surgical and immunosuppressive refinements have led to improved outcomes in simultaneous pancreas-kidney (SPK) transplants. Despite these improvements, early pancreas allograft loss remains not insignificant.…