Articles tagged "Graft failure"

2022 American Transplant Congress
Moral Distress Among Palliative Care and Transplant Clinicians in the Context of Transplant Care
K. Ladin¹, E. Park², J. Perugini², K. Aufort², T. Porteny²
¹Tufts University, Medford, MA, ²REACH Lab, Tufts University, Medford, MA
*Purpose: Despite benefits of palliative care referrals and early advance care planning for patients with end-stage organ disease and recipients experiencing graft failure, few patients…
2022 American Transplant Congress
Clinical Significance of Delayed Graft Function and Slow Graft Function in Living Donor Kidney Transplantation
J. Song¹, S. Jeong¹, S. Min¹, J. Ha¹, J. Lee², J. Jeong³, Y. Kim¹, Y. Kim¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Boramae Medical Center, Seoul, Korea, Republic of, ³Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of
*Purpose: The delayed graft function (DGF) after kidney transplantation (KT) affects long-term graft and patient survival. We explored the time-trend of DGF and associated risk…
2022 American Transplant Congress
Plasmapheresis and Rituximab for Prevention of Focal Segmental Glomerulosclerosis Recurrence Post-Kidney Transplantation
A. N. Yun¹, A. W. Rogers¹, J. C. Krisl¹, A. Kagan², H. E. Adrogue², A. J. Khan², P. Khairallah², S. G. Yi³, M. J. Hobeika³, R. R. McMillan³, H. Podder³, A. O. Gaber³, R. J. Knight³
¹Pharmacy, Houston Methodist Hospital, Houston, TX, ²Nephrology, Houston Methodist Hospital, Houston, TX, ³Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) recurs after kidney transplantation (KT) in 30-50% of recipients with a median time of 1.5 months post-KT. Recurrence is…
2022 American Transplant Congress
Revolutionizing Clinical Diagnostic Models for Acute Rejection Using Generative Adversarial Networks
W. Yazar¹, R. Nijor¹, R. Sarwal¹, N. Titzler¹, M. Sarwal², S. Ghosh¹
¹Nephrosant, Brisbane, CA, ²NephroSant, Brisbane, CA
*Purpose: Data heterogeneity, incompleteness and class-imbalance, hallmarks of real world healthcare data (RWHD), pose long-standing challenges to the accuracy of AI-based models. This research evaluates…
2022 American Transplant Congress
Do Clinical & Pathologic Signs of Rejection Develop Following Transplantation of Tissue Containing Non-Autologous Mitochondria in an Autologous Nuclear Cloned Host?
S. Jacob¹, M. L. Baack², A. Savinov³, P. J. Wettstein⁴
¹Cardiothoracic Surgery and transplantation, Mayo Clinic, Jacksonville, FL, ²Division of Neonatology, University of South Dakota – Sanford School of Medicine, Sioux Falls, SD, ³Sanford Research, University of South Dakota School of Medicine, Sioux Falls, SD, ⁴Departments of Surgery and Immunology, Mayo Clinic, Rochester, MN
*Purpose: Recent studies have yielded conflicting results on the capacity of oocyte-encoded mtDNA polymorphisms to stimulate rejection . Therefore, there are still questions as to…
2022 American Transplant Congress
Clinical Significances Of Anti-collagen Type I And Type Iii Antibodies In Antibody-mediated Rejection
S. Park¹, S. Yang¹, K. Moon¹, J. Ha¹, Y. Kim¹, E. Song¹, H. Lee²
¹Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: It is important to determine the clinical significance of non-human leukocyte antigen (HLA) antibodies and their association with antibody-mediated rejection (ABMR) of kidney allografts.*Methods:…
2022 American Transplant Congress
Protein and Transcriptomic Differences Between High and Low Neointimal Arteries in Human Cardiac Allograft Vasculopathy Rejected Grafts
J. Nevarez-Mejia¹, H. C. Pickering¹, R. A. Sosa¹, R. P. Lau¹, G. A. Fishbein¹, W. M. Baldwin III², R. L. Fairchild², E. F. Reed¹
¹University of California, Los Angeles, Los Angeles, CA, ²Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH
*Purpose: Cardiac allograft vasculopathy (CAV) is the leading cause of graft failure and mortality following heart transplantation. Donor specific antibodies (DSA) contribute to CAV progression…
2022 American Transplant Congress
Transplant Graft TMA Injury Post COVID-19 Vaccination
O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain
Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX
*Purpose: Vaccination against SARS-CoV-2 is essential. Complicating this effort are reports of a suboptimal response to the SARS-CoV-2 spike protein in patients on immunosuppressive medications…
2022 American Transplant Congress
Validation of a Prediction System for Risk of Allograft Loss (iBOX) in Pediatric Kidney Transplant Recipients
J. Hogan¹, G. Divard², R. Garro³, O. Boyer⁴, M. Seifert⁵, J. Smith⁶, B. Toenshoff⁷, K. Twombley⁸, B. Warady⁹, P. Weng¹⁰, R. Zaar¹¹, R. Patzer¹², A. Loupy²
¹Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France, ²Paris Transplant Group, INSERM, Paris, France, ³Pediatric Nephrology, Children Healthcare of Atlanta, Atlanta, GA, ⁴Pediatric Nephrology, Necker Hospital, Paris, France, ⁵UAB School of Medicine, Birmingham, AL, ⁶Pediatric Nephrology, Seattle Children, Seattle, WA, ⁷University Children's Hospital, Heidelberg, Germany, ⁸Medical University of South Carolina, Charleston, SC, ⁹Childrens Mercy Hospital, Kansas City, MO, ¹⁰Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ¹¹Pediatric Nephrology, Le Bonheur Children's Hospital, Memphis, TN, ¹²Emory Transplant Center, Emory University, Atlanta, GA
*Purpose: Kidney allograft loss is a common cause of end-stage renal disease but accurate prediction models of kidney allograft loss are lacking in children. The…
2022 American Transplant Congress
Clinical Significance of the Living Kidney Donor Profile Index in Living Kidney Donors for Predicting of Post-Transplant Outcome: Korean Organ Transplantation Registry
J. Kim¹, D. Kim¹, S. Yoon¹, S. Kang¹, J. Kim¹, H. Hwang¹, K. Jeong¹, H. Ko², C. Jung³, D. Kim⁴, Y. Kim⁵, J. Yang⁶, C. Ahn⁷
¹Department of Nephrology, Kyung Hee University hospital, Seoul, Korea, Republic of, ²Department of Surgery, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ³Department of Transplantation and Vascular Surgery, Korea University Anam Hospital, Seoul, Korea, Republic of, ⁴Department of Surgery, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju, Korea, Republic of, ⁵Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea, Republic of, ⁶Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: According to recent reports, a risk index for living donor kidney transplantation (LDKT) such as the Kidney donor profile index (KDPI), a non-invasive method…

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