2015 American Transplant Congress
Determinants of Accelerated CAV in Heart Allografts: Major Independent Impact of Circulating DSA
Paris Translational Research Center for organ Transplantation, Paris, France.
BackgroundChronic allograft vasculopathy (CAV) is the leading cause of late failing heart allografts and is associated with mortality. The determinants of CAV integrating traditional cardiovascular…2015 American Transplant Congress
Dietary-Associated Trimethylamine N-Oxide (TMAO) Levels Is associated With Coronary Allograft Vasculopathy Following Heart Transplantation
Background: Coronary allograft vasculopathy (CAV) is a leading cause of cardiac graft failure after 1 year post transplant. It is characterized by an inflammatory vascular…2015 American Transplant Congress
Endosome-Based Activation of Non-Canonical NF-kB Signaling By Membrane Attack Complexes
Using sera from transplant patients with high-titer panel reactive antibody (PRA), we previously described a model for studying the effects of alloantibody binding and complement…2015 American Transplant Congress
Oxidative Stress During Organ Recovery Influences Transplant Vasculopathy Development
Transplant vasculopathy is still a major obstacle to long-term graft survival. Pharmacological strategies aiming at preventing it are still lacking. Herein we show that the…2015 American Transplant Congress
Is There a Protective Value for Low Level Donor Specific Antibodies to Prevent Cardiac Allograft Vasculopathy After Heart Transplant?
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Donor specific antibodies (DSA) following heart transplant has been reported to be associated with increased development of cardiac allograft vasculopathy (CAV) and risk of…
American Transplant Congress abstracts