2015 American Transplant Congress
Long-Term Results After Heart Transplantation – A Randomized Trial Comparing Tacrolimus Versus Cyclosporine A in Combination With Mycophenolate Mofetil After a Mean Duration of 15 Years
Purpose. Development of cardiac allograft vasculopathy (CAV), renal dysfunction and malignancies are the main risks due to long-term immunosuppressive therapy after heart transplantation (HTx). We…2015 American Transplant Congress
Selective CD28 Blockade With or Without CD40-CD154 Blockade Promotes Cardiac Allograft Protection in Non-Human Primates
1Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM, U643, Nants, France.
Aim: Selective targeting CD28:B7 costimulation without interfering with CTLA-4-dependent immune regulation is theoretically an attractive approach to modulate pathogenic T cell-dependent immunity. We previously reported…2015 American Transplant Congress
Predictive Value of Regadenoson Scans After Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Cardiac allograft vasculopathy (CAV) is one of the major factors limiting long-term survival after heart transplantation. The use of annual coronary angiograms is an…2015 American Transplant Congress
Modeling the Clinical and Cost-Effectiveness of Dobutamine Stress Echocardiography With Confirmatory Coronary Angiography for the Diagnosis of Pediatric Cardiac Allograft Vasculopathy
The Cardiac Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Purpose: Cardiac allograft vasculopathy (CAV) is a leading cause of long-term mortality after pediatric heart transplantation. The gold standard of diagnosis is coronary angiography, an…2015 American Transplant Congress
Determinants of Accelerated CAV in Heart Allografts: Major Independent Impact of Circulating DSA
Paris Translational Research Center for organ Transplantation, Paris, France.
BackgroundChronic allograft vasculopathy (CAV) is the leading cause of late failing heart allografts and is associated with mortality. The determinants of CAV integrating traditional cardiovascular…
American Transplant Congress abstracts