2017 American Transplant Congress
High Titer De Novo Donor-Specific HLA Alloantibodies and Cardiac Allograft Vasculopathy After Pediatric Heart Transplantation.
Background: Cardiac allograft vasculopathy (CAV) continues to be a limiting factor in long-term survival after pediatric heart transplantation (HT). Criteria for early diagnosis of CAV…2017 American Transplant Congress
Reliability of Donor Kidney Biopsies from Time of Organ Recovery Compared to Immediate Post-Reperfusion Biopsies.
University of Michigan, Ann Arbor
Frozen section or rapid permanent biopsies of donor kidneys are frequently obtained for higher risk kidneys. We sought to investigate agreement between the procurement donor…2017 American Transplant Congress
Role of HMG CoA Reductase Inhibitors on Time to Development of Chronic Lung Allograft Dysfunction Post-Lung Transplant.
Duke University Hospital, Durham, NC
Purpose: Five-year survival after lung transplant (LT) is approximately 55%. Chronic lung allograft dysfunction (CLAD) is a primary contributor to this reduced survival post-LT. Options…2016 American Transplant Congress
Complement-Binding Donor-Specific Anti-HLA Antibodies Are Associated with Severe Kidney Allograft Arteriosclerosis.
The role of circulating donor-specific anti-HLA antibodies (DSA) in the development of accelerated arteriosclerosis have been recently reported in kidney transplant recipients. This study investigated…2016 American Transplant Congress
Air Pollution – An Additional Risk Factor for Developing Cardiac Allograft Vasculopathy.
Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Purpose:Cardiac allograft vasculopathy (CAV) remains one of the primary causes of death in long-term follow-up after heart transplantation (HTx) and is the most limiting factor…2016 American Transplant Congress
Conditional Deletion of mTOR in Myeloid Cells Inhibits Chronic Allograft Rejection – A Novel Role for Macrophages in Transplant Vasculopathy.
Most transplants eventually lost to chronic rejection under potent immunosuppression therapies where activation of innate immunity is suspected to play a major role in graft…2015 American Transplant Congress
Selective CD28 Blockade With or Without CD40-CD154 Blockade Promotes Cardiac Allograft Protection in Non-Human Primates
1Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM, U643, Nants, France.
Aim: Selective targeting CD28:B7 costimulation without interfering with CTLA-4-dependent immune regulation is theoretically an attractive approach to modulate pathogenic T cell-dependent immunity. We previously reported…2015 American Transplant Congress
Predictive Value of Regadenoson Scans After Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Cardiac allograft vasculopathy (CAV) is one of the major factors limiting long-term survival after heart transplantation. The use of annual coronary angiograms is an…2015 American Transplant Congress
Modeling the Clinical and Cost-Effectiveness of Dobutamine Stress Echocardiography With Confirmatory Coronary Angiography for the Diagnosis of Pediatric Cardiac Allograft Vasculopathy
The Cardiac Center, Children's Hospital of Philadelphia, Philadelphia, PA.
Purpose: Cardiac allograft vasculopathy (CAV) is a leading cause of long-term mortality after pediatric heart transplantation. The gold standard of diagnosis is coronary angiography, an…2015 American Transplant Congress
Determinants of Accelerated CAV in Heart Allografts: Major Independent Impact of Circulating DSA
Paris Translational Research Center for organ Transplantation, Paris, France.
BackgroundChronic allograft vasculopathy (CAV) is the leading cause of late failing heart allografts and is associated with mortality. The determinants of CAV integrating traditional cardiovascular…
American Transplant Congress abstracts