ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft acceptance"

  • 2016 American Transplant Congress

    Outcomes with the Use of Pediatric Donor Livers in Adult Recipients: Review of the UNOS Database.

    K. Croome, D. Lee, J. Burns, J. Nguyen, D. Perry, C. Taner.

    Transplant, Mayo Clinic Florida, Jacksonville, FL.

    Background: While there is an agreement that pediatric donor (PD) livers should ideally be used for pediatric recipients, there remain some situations where these livers…
  • 2016 American Transplant Congress

    The Use of Kidneys with Acute Kidney Injury: The Good, the Bad and the Ugly.

    C. Boffa,1,2 F. van de Leemkolk,1 E. Curnow,3 J. Gilbert,2 E. Sharples,1,2 R. Ploeg.1,2

    1Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospital Trust, Oxford, United Kingdom; 3Department of Statistics, NHS Blood and Transplant, Bristol, United Kingdom.

    Introduction:The widening gap between supply and demand in kidney transplantation has lead to the increased use of kidneys from marginal donors, including those with acute…
  • 2015 American Transplant Congress

    Poor Renal Function and Increased Mortality in Elderly Recipients of Deceased Donor Kidneys from Elderly Donors

    S. Berger,1 H. Peters-Sengers,2 M. Heemskerk,3 F. Bemelman,2 J. Homan van der Heide.2

    1Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands; 2Department of Nephrology, Academic Medical Center, Amsterdam, Netherlands; 3Dutch Transplant Foundation, Leiden, Netherlands.

    Background: Within the Eurotransplant Senior Program kidneys form donors older than 65 both after cardiac death (DCD) or brain death (DBD) are allocated to recipients…
  • 2015 American Transplant Congress

    Donor Specific Tolerance Can Be Induced by Donor Bone Marrow Transfer With Activation of Invariant Naturel Killer T Cells

    S. Miyairi,1 T. Hirai,1 R. Shibahara,1 K. Omoto,1 S. Nunoda,2 K. Yamazaki,2 Y. Ishii,3 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; 2Cardiovascular Surgery, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; 3Laboratory of Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.

    It has been reported that liposomal formulation of a-galactosylceramide(lipo-aGC) could induce antigen specific regulatory T cells (Treg) in vivo when administered with particular antigens. We…
  • 2015 American Transplant Congress

    Human Hematopoietic Chimeric Cells as a Novel Approach for Tolerance Induction After Transplantation

    E. Bryndza Tfaily,1 J. Cwykiel,1 K. Dastych,2 A. Sklodowska,1 M. Siemionow.1

    1Orthopaedics, University of Illinois at Chicago, Chicago, IL; 2Pathology, University of Illinois at Chicago, Chicago, IL.

    Background: Cellular therapies represent a new promising approach for transplant tolerance induction. One of the methods for immune response modulation in solid organ and vascularized…
  • 2015 American Transplant Congress

    Is the Pulsatile Kidney Preservation Machine a Vaulable Tool in Evaluating Kidney Suitability from Older Donors After Brain Death?

    D. Paredes Zapata,1 A. Ruiz Arranz,1 C. Rodriguez Villar,1 L. Peri Cussi,2 A. Alcaraz Asensio,2 R. Adalia Bartolome,1 F. Oppenheimer Salinas.3

    1Donation and Transplant Coordination Section, Hospital Clinic, University of Barcelona, Barcelona, Spain; 2Urology Department, Hospital Clinic, University of Barcelona, Barcelona, Spain; 3Renal Transplant Unit, Hospital Clinic, Barcelona, Spain.

    Introduction: Donors after Brain Death (DBD) older than 60 years old, have become 46.8% of our donor activity, with higher Discard Rate (DR). Assessment of…
  • 2015 American Transplant Congress

    In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury

    K. Famulski,1 S. Niederhaus,2 J. Reeve,1 J. Bromberg,2 P. Halloran.1

    1University of Alberta, Edmonton, Canada; 2University of Marlyland, Baltimore.

    Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…
  • 2015 American Transplant Congress

    Anti-LG3 Antibodies Aggravate Ischemia-Reperfusion Injury

    B. Yang,1 K. Hamelin,1 L. Pomerleau,1 J. Peng,1 J. Tremblay,1 N. Patey,2 M.-J. Hébert.1

    1Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) and Université de Montréal, Montréal, Canada; 2Department of Pathology, CHU Ste-Justine Université de Montréal, Montréal, Canada.

    Ischemia-Reperfusion Injury (IRI) is a significant cause of renal allograft dysfunction and a risk factor for poor long-term graft outcomes. Microvascular injury is an important…
  • 2015 American Transplant Congress

    Implication of Intragraft γδ T Cell Profiles in Operational Tolerance After Clinical Transplantation of Highly Immunogenic Intestine -Difference from Immunoprivileged Liver

    Y. Li,1 X. Zhao,1 H. Ohe,2 H. Nafady-Hego,3 A. Bishop,4 J. Pirenne,5 T. Koshiba.6

    1Kyoto University, Kyoto, Japan; 2Matsue Red Cross Hospital, Matsue, Japan; 3Assiut Universty, Assiut, Egypt; 4University of Sydney, Sydney, Australia; 5University of Leuven, Leuven, Belgium; 6Fukushima Medical University, Fukushima, Japan.

    (Background) T-cell receptor (TCR) Vδ2 γ δ T cells (Vδ 2 cells) participate in host defense, whereas Vδ 1 γ δ T cells (Vδ 1…
  • 2015 American Transplant Congress

    Alloimmune Regulation and Long-Term Allograft Survival Induced by Short-Term Administration of Chinese Medicine Cornus Officinalis and Cuscuta Sinensis Lam

    Z. Dai, Y. Zeng, X. Liu, Z. Chuan.

    Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.

    Achieving long-term allograft survival or tolerance without continuously global immunosuppression is a highly desirable goal. This study is to induce long-term allograft survival without long-term…
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