Articles tagged "Glomerulonephritis"

2020 American Transplant Congress
Recurrence of Igg3Lambda Restricted Cryoglobulinemic Glomerulonephritis in a Renal Allograft: Resolution after Daratumumab Treatment
S. C. Jordan, R. Vescio, J. Hou, N. Ammerman, R. Najjar, S. Sethi, E. Huang, A. Peng, A. Vo
Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: C3GN encompasses a group of renal diseases often associated with paraproteinemias. Recurrence in renal allografts is reported. Currently, there are no effective or curative…
2020 American Transplant Congress
Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy
Y. Caliskan¹, B. Dirim², E. Aksoy², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
2020 American Transplant Congress
The Association between Alloimmunity and De Novo Glomerulonephritis Post Kidney Transplantation
P. Khairallah, J. Kamal, E. Vasilescu, I. Batal, G. Dube
Columbia University Medical Center, New York, NY
*Purpose: In contrast to recurrent immune complex-mediated glomerulonephritis (ICGN), de novo ICGN of the allograft is poorly characterized. We hypothesize that alloimmunity results in immune-complex…
2020 American Transplant Congress
Hydroxychloroquine is Associated with Better Patient and Graft Survival in Kidney Transplant Patients with Lupus Nephritis as Cause of ESRD
T. Singh¹, S. Garg², S. Panzer¹
¹Nephrology, University of Wisconsin, Madison, WI, ²Rheumatology, University of Wisconsin, Madison, WI
*Purpose: Hydroxychloroquine (HCQ) use leads to better patient and renal survival in patients with lupus nephritis (LN). Whether the clinical benefits of HCQ extends to…
2019 American Transplant Congress
Risk Factors for Recurrence and Predictors of Response in Kidney Transplant Recipients with Primary FSGS
A. Uffing¹, T. TANGO-consortium², P. Cravedi³, L. V. Riella¹
¹Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²NA, Boston, MA, ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently recurs after kidney transplantation. Several circulating factors have been proposed to cause recurrence…
2019 American Transplant Congress
IgG Glycosylation Causes Podocyte Injury in Transplant Glomerulopathy through Calcium Calmodulin Kinase IV
R. Bhargava, K. Maeda, M. Pavlakis, G. Tsokos
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
*Purpose: Transplant glomerulopathy(TG) is a major cause of late allograft loss. Increase in urine podocin/creatinine ratio in TG signifies acceleration of podocyte detachment from glomerular…
2019 American Transplant Congress
Conversion to Belatacept in Kidney Transplant Recipients with Systemic Lupus Erythematosus
I. Carrión Barberà, M. C. Fajardo, D. Tsapepas, J. Gartshteyn, A. Askanase, H. E. Fernandez
Columbia University MC, New York, NY
*Purpose: Lupus nephritis (LN) results in the need for renal replacement therapy (RRT) in 10-30% of LN pts and 30% receive a kidney transplant (KT).…
2019 American Transplant Congress
De Novo Glomerulonephritis after Non Renal Abdominal Organ Transplantation
C. Farkas¹, R. B. Ettenger¹, J. Zuckerman², R. S. Venick³, P. Weng¹
¹Pediatric Nephrology, UCLA, Los Angeles, CA, ²Pathology, UCLA, Los Angeles, CA, ³Pediatric Gastroenterology, UCLA, Los Angeles, CA
*Purpose: Pediatric recipients of non renal abdominal organs may develop renal abnormalities of uncertain etiology. We describe for the first time de novo lupus-like glomerulonephritis…
2019 American Transplant Congress
Beneficial Association between Renin-Angiotensin-Aldosterone-System Blockade Usage and Graft Prognosis in Allograft Immunoglobulin A Nephropathy
S. Park¹, C. Baek², M. Yu³, Y. Kim¹, J. Moon¹, H. Go², Y. Kim², J. Lee⁴, S. Min¹, J. Ha¹, K. Moon¹, Y. Kim¹, C. Ahn¹, S. Park², H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Asan Medical Center, Seoul, Korea, Republic of, ³Hanyang University Hospital, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Boramae Medical Center, Seoul, Korea, Republic of
*Purpose: Although immunoglobulin A nephropathy (IgAN) is associated with a high risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB)…
2019 American Transplant Congress
Clinical Importance of the Updated Oxford Classification in Allograft IgA Nephropathy
S. Park¹, H. Go², C. Baek², J. Jeong¹, Y. Kim¹, Y. Kim¹, Y. Kim², J. Lee³, S. Min¹, J. Ha¹, E. Song¹, Y. Kim¹, S. Park², K. Moon¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Asan Medical Center, Seoul, Korea, Republic of, ³Seoul National University Hospital, Boramae Medical Center, Seoul, Korea, Republic of
*Purpose: An additional investigation on the clinical significance of the updated Oxford classification in allograft IgA nephropathy (IgAN) is warranted.*Methods: We performed a retrospective cohort…