Articles tagged "Glomerulonephritis"

2020 American Transplant Congress
Pathological Characteristics of BK Polyomavirus Nephropathy with Glomerular Involvement
G. Huang¹, X. Chen¹, W. Chen², S. Yang², J. Qiu¹
¹Department of Organ Transplantation, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China, ²Department of Pathology, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China
*Purpose: This study aimed to investigate the pathological characteristics of BK polyomavirus-associated nephropathy with glomerular involvement in kidney transplant recipients.*Methods: Forty-four patients with glomerular BK…
2020 American Transplant Congress
Are Molecular Diagnoses of Antibody Mediated Rejection (ABMR) Reliable in the Setting of Antibody-Antigen Complex Mediated Tissue Injury Unrelated to Alloimmunity?
P. Randhawa¹, Y. Huang¹, G. Tseng², K. Xiao³
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ³Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, Pittsburgh, PA
*Purpose: Transcriptomics based tests for ABMR are now available commercially. The reliability of these tests in clinical settings where allograft tissue is damaged by antibody-antigen…
2020 American Transplant Congress
Glomerular C4d in Post-Transplant IgA Glomerulonephritis is Associated with Decreased Allograft Survival
Z. Kikic, H. Omic, B. Perschl, G. Böhmig, N. Kozakowski, M. Eder
Medical University of Vienna, Vienna, Austria
*Purpose: Post transplant (pTX) glomerulonephritis (GN) is an important factor contributing to early and late allograft failure. De novo or recurrent IgA GN are the…
2020 American Transplant Congress
Risk Factors and Treatment of Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation
G. Chen, C. Wang, Z. Wu, X. Liu, Q. Li, L. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Recurrent focal segmental glomerulosclerosis(FSGS) is common after kidney transplantation . We conducted a retrospective cohort study with the aim to investigating the risk factors…
2019 American Transplant Congress
Risk Factors for Recurrence and Predictors of Response in Kidney Transplant Recipients with Primary FSGS
A. Uffing¹, T. TANGO-consortium², P. Cravedi³, L. V. Riella¹
¹Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²NA, Boston, MA, ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently recurs after kidney transplantation. Several circulating factors have been proposed to cause recurrence…
2019 American Transplant Congress
IgG Glycosylation Causes Podocyte Injury in Transplant Glomerulopathy through Calcium Calmodulin Kinase IV
R. Bhargava, K. Maeda, M. Pavlakis, G. Tsokos
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
*Purpose: Transplant glomerulopathy(TG) is a major cause of late allograft loss. Increase in urine podocin/creatinine ratio in TG signifies acceleration of podocyte detachment from glomerular…
2019 American Transplant Congress
Conversion to Belatacept in Kidney Transplant Recipients with Systemic Lupus Erythematosus
I. Carrión Barberà, M. C. Fajardo, D. Tsapepas, J. Gartshteyn, A. Askanase, H. E. Fernandez
Columbia University MC, New York, NY
*Purpose: Lupus nephritis (LN) results in the need for renal replacement therapy (RRT) in 10-30% of LN pts and 30% receive a kidney transplant (KT).…
2019 American Transplant Congress
De Novo Glomerulonephritis after Non Renal Abdominal Organ Transplantation
C. Farkas¹, R. B. Ettenger¹, J. Zuckerman², R. S. Venick³, P. Weng¹
¹Pediatric Nephrology, UCLA, Los Angeles, CA, ²Pathology, UCLA, Los Angeles, CA, ³Pediatric Gastroenterology, UCLA, Los Angeles, CA
*Purpose: Pediatric recipients of non renal abdominal organs may develop renal abnormalities of uncertain etiology. We describe for the first time de novo lupus-like glomerulonephritis…
2019 American Transplant Congress
Beneficial Association between Renin-Angiotensin-Aldosterone-System Blockade Usage and Graft Prognosis in Allograft Immunoglobulin A Nephropathy
S. Park¹, C. Baek², M. Yu³, Y. Kim¹, J. Moon¹, H. Go², Y. Kim², J. Lee⁴, S. Min¹, J. Ha¹, K. Moon¹, Y. Kim¹, C. Ahn¹, S. Park², H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Asan Medical Center, Seoul, Korea, Republic of, ³Hanyang University Hospital, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Boramae Medical Center, Seoul, Korea, Republic of
*Purpose: Although immunoglobulin A nephropathy (IgAN) is associated with a high risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB)…
2019 American Transplant Congress
Clinical Importance of the Updated Oxford Classification in Allograft IgA Nephropathy
S. Park¹, H. Go², C. Baek², J. Jeong¹, Y. Kim¹, Y. Kim¹, Y. Kim², J. Lee³, S. Min¹, J. Ha¹, E. Song¹, Y. Kim¹, S. Park², K. Moon¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Asan Medical Center, Seoul, Korea, Republic of, ³Seoul National University Hospital, Boramae Medical Center, Seoul, Korea, Republic of
*Purpose: An additional investigation on the clinical significance of the updated Oxford classification in allograft IgA nephropathy (IgAN) is warranted.*Methods: We performed a retrospective cohort…