Articles tagged "Glomerulonephritis"

2020 American Transplant Congress
Risk Factors and Treatment of Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation
G. Chen, C. Wang, Z. Wu, X. Liu, Q. Li, L. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Recurrent focal segmental glomerulosclerosis(FSGS) is common after kidney transplantation . We conducted a retrospective cohort study with the aim to investigating the risk factors…
2020 American Transplant Congress
Recurrence of Igg3Lambda Restricted Cryoglobulinemic Glomerulonephritis in a Renal Allograft: Resolution after Daratumumab Treatment
S. C. Jordan, R. Vescio, J. Hou, N. Ammerman, R. Najjar, S. Sethi, E. Huang, A. Peng, A. Vo
Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: C3GN encompasses a group of renal diseases often associated with paraproteinemias. Recurrence in renal allografts is reported. Currently, there are no effective or curative…
2020 American Transplant Congress
Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy
Y. Caliskan¹, B. Dirim², E. Aksoy², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
2020 American Transplant Congress
Hydroxychloroquine is Associated with Better Patient and Graft Survival in Kidney Transplant Patients with Lupus Nephritis as Cause of ESRD
T. Singh¹, S. Garg², S. Panzer¹
¹Nephrology, University of Wisconsin, Madison, WI, ²Rheumatology, University of Wisconsin, Madison, WI
*Purpose: Hydroxychloroquine (HCQ) use leads to better patient and renal survival in patients with lupus nephritis (LN). Whether the clinical benefits of HCQ extends to…
2020 American Transplant Congress
The Association between Alloimmunity and De Novo Glomerulonephritis Post Kidney Transplantation
P. Khairallah, J. Kamal, E. Vasilescu, I. Batal, G. Dube
Columbia University Medical Center, New York, NY
*Purpose: In contrast to recurrent immune complex-mediated glomerulonephritis (ICGN), de novo ICGN of the allograft is poorly characterized. We hypothesize that alloimmunity results in immune-complex…
2020 American Transplant Congress
Pathological Characteristics of BK Polyomavirus Nephropathy with Glomerular Involvement
G. Huang¹, X. Chen¹, W. Chen², S. Yang², J. Qiu¹
¹Department of Organ Transplantation, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China, ²Department of Pathology, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China
*Purpose: This study aimed to investigate the pathological characteristics of BK polyomavirus-associated nephropathy with glomerular involvement in kidney transplant recipients.*Methods: Forty-four patients with glomerular BK…
2020 American Transplant Congress
Are Molecular Diagnoses of Antibody Mediated Rejection (ABMR) Reliable in the Setting of Antibody-Antigen Complex Mediated Tissue Injury Unrelated to Alloimmunity?
P. Randhawa¹, Y. Huang¹, G. Tseng², K. Xiao³
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ³Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, Pittsburgh, PA
*Purpose: Transcriptomics based tests for ABMR are now available commercially. The reliability of these tests in clinical settings where allograft tissue is damaged by antibody-antigen…
2020 American Transplant Congress
Glomerular C4d in Post-Transplant IgA Glomerulonephritis is Associated with Decreased Allograft Survival
Z. Kikic, H. Omic, B. Perschl, G. Böhmig, N. Kozakowski, M. Eder
Medical University of Vienna, Vienna, Austria
*Purpose: Post transplant (pTX) glomerulonephritis (GN) is an important factor contributing to early and late allograft failure. De novo or recurrent IgA GN are the…
2019 American Transplant Congress
Risk Factors for Recurrence and Predictors of Response in Kidney Transplant Recipients with Primary FSGS
A. Uffing¹, T. TANGO-consortium², P. Cravedi³, L. V. Riella¹
¹Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²NA, Boston, MA, ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently recurs after kidney transplantation. Several circulating factors have been proposed to cause recurrence…
2019 American Transplant Congress
IgG Glycosylation Causes Podocyte Injury in Transplant Glomerulopathy through Calcium Calmodulin Kinase IV
R. Bhargava, K. Maeda, M. Pavlakis, G. Tsokos
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
*Purpose: Transplant glomerulopathy(TG) is a major cause of late allograft loss. Increase in urine podocin/creatinine ratio in TG signifies acceleration of podocyte detachment from glomerular…