2019 American Transplant Congress
Long Term Renal Function Following Islet Transplantation in the Clinical Islet Transplantation Consortium
*Purpose: Islet transplantation (IsletTp) is safe and effective treatment of Type 1 diabetes complicated by severe hypoglycemia (Diabetes Care 2016, 39:1230). But the requirement for…2019 American Transplant Congress
Mathematical Model of Post-Transplant Serum Creatinine
*Purpose: Commonly used equations calculating eGFR are not applicable when serum creatinine (Scr) is rapidly changing such as the post-transplant period. The purpose of this…2019 American Transplant Congress
Rapid Detection of Kidney Transplant Injury by Quantifying Donor-Derived Cell-Free Deoxyribonucleic Acid via Massively Multiplex Polymerase Chain Reaction
1University of California San Francisco, San Francisco, CA, 2Natera Inc., San Carlos, CA
*Purpose: Plasma donor-derived cell-free DNA (dd-cfDNA) is a proven marker for allograft rejection in patients with kidney transplant (KT). Our goal was to assess performance…2019 American Transplant Congress
Comparison Of Estimating Glomerular Filtration Equations In Living Kidney Donor Candidates Prior To Donation
*Purpose: Serum creatinine-based estimated glomerular filtration rate (eGFR) models have been shown to over- or underestimate measured iohexol GFR (mGFR), but it is unclear if…2019 American Transplant Congress
The Combination of 3-Month Estimated Glomerular Filtration Rate and Proteinuria is a Valuable Tool for Evaluating Long-Term Kidney Graft Survival
*Purpose: Estimated glomerular filtration rate (eGFR) measured at 1 year is the usual outcome used to predict the long-term graft survival in the field of…2019 American Transplant Congress
Does Proton Pump Inhibitor Use Affect Renal Function in Kidney Transplant Recipients?
*Purpose: Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. In the setting of renal transplantation, it…2019 American Transplant Congress
Subclinical Rejection by Biopsy or Gene Expression Profile Predicts Long Term Kidney Function in Patients in the CTOT08 Trial
*Purpose: The CTOT08 trial showed that either histological subAR or positive gene expression profile (GEP) in the blood associated with histological subAR correlated with a…2019 American Transplant Congress
The Association of Estimated Glomerular Filtration Rate at One Year Post-Kidney Transplant with Graft Loss is Not Modified by Delayed Graft Function
University of British Columbia, Vancouver, BC, Canada
*Purpose: In kidney transplant recipients, eGFR at 1 year post-transplant has been shown to be associated with graft loss, but it is unclear if this…2019 American Transplant Congress
Evidence to Support the Use of Kidney Allograft Function as a Clinical Trial Outcome Measure
Nephrology, University of British Columbia, Vancouver, BC, Canada
*Purpose: As a biomarker, kidney allograft function has been rejected as clinical trial outcome measure because it is not predictive of allograft survival. In this…2019 American Transplant Congress
Recipient and Donor Factors at the Time of Transplant as Predictors of Graft Outcomes
*Purpose: As the ESRD population ages and the impetus to increase utilization of donor organs grows, we aimed to evaluate the impact of donor and…
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