2016 American Transplant Congress
Association Between GFR Decline and Long Term Outcome in Renal Transplantation.
1Nephrology Department, CHU, Saint Etienne, France; 2Nephrology Department, CHU, Nimes, France.
In renal transplantation, GFR decline is strongly associated to graft failure and patient death and thus could be an interesting proxy for clinical research. GFR…2016 American Transplant Congress
Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.
Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…2016 American Transplant Congress
Role of Natural Killer Cells in Kidney Transplant Outcome.
Aim of the study was to evaluate the relationship between killer cell immunoglobulin-like receptor (KIR) phenotype and kidney transplant rejection. NK-target cell interaction depends on…2016 American Transplant Congress
Quadruple Induction Regimen with Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Improves Graft Function without Increase in the Incidence of Microvascular Inflammation or De Novo Donor Specific Antibody Compared to the Standard Triple Regimen.
Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant problem even with low exposure regimens. On the other hand, CNI-free regimen…2016 American Transplant Congress
Pulse Pressure and GFR Decay in Kidney Transplant Recipients.
Single blood pressure values have commonly been used to assess the risk of allograft failure in kidney transplant recipients. In this analysis we prospectively evaluated…2016 American Transplant Congress
The BEST Trial: A Prospective Randomized Trial of Belatacept-Based, CNI- and Corticosteroid-Free Immunosuppression.
Efficacy of CNI- and corticosteroid-free immunosuppressive regimens has not been demonstrated in large, multicenter trials. BEST (Belatacept-based Early Steroid Withdrawal Trial) (NCT 01729494) compares 2…2016 American Transplant Congress
Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.
Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…2016 American Transplant Congress
Renal Dysfunction at 12 Months Is Not Associated with Everolimus Exposure in De Novo Renal Transplant Recipients.
Renal dysfunction at 1 year post-transplantation is associated with poor graft outcome. Here, we assess post-transplant renal function associated with everolimus (EVR) and tacrolimus (TAC)…2016 American Transplant Congress
The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.
University of Virginia, Charlottesville, VA.
Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…2016 American Transplant Congress
Kidney Donor Profile Index and Recipient BMI Are Potent Predictors of Six Month Deceased Donor eGFR as Opposed to EPTS.
University of Virginia Health System, Charlottesville, VA.
Background: Kidney Donor Profile Index (KDPI) has been shown to be predictive of both short and long term graft survival and is used by transplant…
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