Articles tagged "Glomerular filtration rate (GFR)"

2016 American Transplant Congress
Angiotensin II Blockade and Fibroblast Growth Factor-23 in Stable Kidney Transplant Recipients.
O. Sanchez, S. Reule, S. Li, D. Berglund, R. Spong, H. Ibrahim.
U of MN, Mpls.
Introduction: FGF-23 has been linked to allograft failure. However, careful serial profiling of FGF-23 has not been done. Therefore, we measured FGF-23 levels in recipients…
2016 American Transplant Congress
A 30% Decrease in Post-kidney Transplant Estimated Glomerular Filtration Rate (eGFR) from 6 Mo-2 Y Is a Surrogate for 5 Y eGFR: Results from Clinical Trials in Organ Transplantation-(CTOT)-17.
G. Faddoul,¹ G. Nadkarni,¹ D. Hricik,² P. Heeger,¹ CTOT17 Investigators.
¹Medicine and Recanati Miller Transplant Institute, Icahn School of Medicine, NY, NY; ²Medicine, Case Medical Center, Cleveland, OH.
Predicting long-term kidney allograft outcomes using early clinical/biomarker data could guide individualized therapy. Emerging evidence in progressive native kidney disease indicates >30% decrease in eGFR…
2016 American Transplant Congress
Surveillance Renal Allograft Biopsies Prognosticate Graft Function.
J. Thompson, D. Taber, P. Baliga, K. Chavin, T. Srinivas.
MUSC, Charleston, SC.
Background: Surveillance biopsy of the renal allograft provides a window into the health of the allograft and could allow prognostication of function by affording better…
2016 American Transplant Congress
Fluctuation of Renal Function During the First Year Is Associated with Negative Impact on Long-Term Kidney Graft Survival: A Retrospective, Propensity Score-Matched Study.
H. Choi,¹ D. Joo,^2,3 M. Song,⁴ M. Kim,^2,3 Y. Kim,^2,3 B. Kim.^1,3
¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; ²Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ³The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ⁴Department of Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
Background: Post-transplant renal function in the first year has been reported to predict long-term renal graft survival. The present study examined whether the fluctuation of…
2016 American Transplant Congress
Activated Cytoprotective Mechanisms in DBD Kidneys Correlate with Kidney Function in Transplant Recipients: A Study Using Clinical Samples from the UK QUOD Biobank.
M. Kaisar,¹ L. van Dullemen,² Z. Akhtar,¹ M. Lo Faro,¹ H. Huang,¹ H. Leuvenink,² B. Kessler,¹ R. Ploeg.¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; ²UMCG, UMCG, Groningen, Netherlands.
The onset of abnormal pathophysiological changes following brain death adversely impact kidney function following transplantation. Understanding the biological mechanisms that affect kidney quality will allow…
2016 American Transplant Congress
Differential Characteristics of Kidney Transplant Recipients According to 1-Year Chronic Kidney Disease Stage 3a and Stage 3b Graft Function.
C. Baek,¹ H. Kim,¹ W. Yang,¹ D. Han,² S.-K. Park.¹
¹Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; ²Department of Surgery, Asan Medical Center, Seoul, Republic of Korea.
Background: The outcomes of transplantation have been improved, but more than 50% of kidney transplantation recipients were still reported to have renal function of chronic…
2016 American Transplant Congress
Acute Kidney Injury (AKI) Associated with Chronic Kidney Disease (CKD) in Paediatric Non-Kidney Transplant Recipients.
C. Williams,^1,2 K. Borges,² T. Banh,² J. Vasilevska-Ristovska,² R. Chanchlani,^1,2 V. Ng,^1,2 A. Dipchand,^1,2 M. Solomon,^1,2 D. Hebert,^1,2 S. Kim,^1,3 B. Astor,⁴ R. Parekh.^1,2,3
¹University of Toronto, Toronto, Canada; ²Hospital for Sick Children, Toronto, Canada; ³University Health Network, Toronto, Canada; ⁴University of Wisconsin, Madison.
Background: Kidney dysfunction is common after solid organ transplantation; however, rates of post-transplant AKI and CKD in children are unknown.Objective: Determine rates of AKI and…
2016 American Transplant Congress
United States versus Australia: Is "Percentage Decline in Estimated Glomerular Filtration Rate" Truly a Surrogate Outcome in Graft Survival?
K. Parker,² A. Rice,¹ A. Kirby,¹ M. Pinion,¹ K. Parker.²
¹Internal Medicine Division of Nephrology and Hypertension, East Carolina University, Greenville, NC; ²Internal Medicine, Vidant Medical Center, Greenville, NC.
Purpose: A previous study conducted in Australia and New Zealand examined the utility of estimated glomerular filtration rate (eGFR) decline as a surrogate marker for…
2016 American Transplant Congress
Association Between GFR Decline and Long Term Outcome in Renal Transplantation.
A. Delay,¹ O. Moranne,² N. Maillard,¹ E. Alamartine,¹ C. Mariat.¹
¹Nephrology Department, CHU, Saint Etienne, France; ²Nephrology Department, CHU, Nimes, France.
In renal transplantation, GFR decline is strongly associated to graft failure and patient death and thus could be an interesting proxy for clinical research. GFR…
2016 American Transplant Congress
Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.
J. Ramirez,¹ E. Cuevas,¹ J. Furuzawa,² L. Morales-Buenrostro,³ M. Lopez-Cervantes,² J. Alberu.¹
¹Transplantation, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ²Immunology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ³Nephrology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ⁴Medicine School, UNAM, Mexico City, Mexico.
Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…