2016 American Transplant Congress
Pulse Pressure and GFR Decay in Kidney Transplant Recipients.
Single blood pressure values have commonly been used to assess the risk of allograft failure in kidney transplant recipients. In this analysis we prospectively evaluated…2016 American Transplant Congress
The BEST Trial: A Prospective Randomized Trial of Belatacept-Based, CNI- and Corticosteroid-Free Immunosuppression.
Efficacy of CNI- and corticosteroid-free immunosuppressive regimens has not been demonstrated in large, multicenter trials. BEST (Belatacept-based Early Steroid Withdrawal Trial) (NCT 01729494) compares 2…2016 American Transplant Congress
Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.
Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…2016 American Transplant Congress
Renal Dysfunction at 12 Months Is Not Associated with Everolimus Exposure in De Novo Renal Transplant Recipients.
Renal dysfunction at 1 year post-transplantation is associated with poor graft outcome. Here, we assess post-transplant renal function associated with everolimus (EVR) and tacrolimus (TAC)…2016 American Transplant Congress
The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.
University of Virginia, Charlottesville, VA.
Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…2016 American Transplant Congress
Kidney Donor Profile Index and Recipient BMI Are Potent Predictors of Six Month Deceased Donor eGFR as Opposed to EPTS.
University of Virginia Health System, Charlottesville, VA.
Background: Kidney Donor Profile Index (KDPI) has been shown to be predictive of both short and long term graft survival and is used by transplant…2016 American Transplant Congress
The Relationship Between Kidney Donor Profile Index and Six Month eGFR in Deceased Donor Recipients.
Division of Nephrology, University of Virginia, Charlottesville, VA.
Kidney function, as measured by GFR, at 6 months post-kidney transplant is a powerful predictor of long-term post-transplant outcomes. This study sought to understand the…2016 American Transplant Congress
Post-Donation eGFR and Hypertension in Living Kidney Donors.
1JHU, Baltimore; 2University of Alabama, Birmingham, Birmingham.
Donor eGFR declines sharply after living kidney donation, but long-term eGFR trajectories and their relationship to post-donation hypertension are poorly understood.METHODS: We retrospectively obtained 7805…2016 American Transplant Congress
Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.
MedStar Georgetown Transplant Institute, Washington, DC.
Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…2016 American Transplant Congress
Associations of Perfusate Biomarkers and Pump Parameters with Delayed Graft Function and Deceased-Donor Kidney Allograft Function.
Hypothermic machine perfusion (HMP) is increasingly used in deceased-donor kidney transplantation, but controversy exists regarding the value of perfusion biomarkers and pump parameters for assessing…
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