ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Glomerular filtration rate (GFR)"

  • 2019 American Transplant Congress

    Rapid Detection of Kidney Transplant Injury by Quantifying Donor-Derived Cell-Free Deoxyribonucleic Acid via Massively Multiplex Polymerase Chain Reaction

    T. K. Sigdel1, F. Acosta2, S. Navarro2, B. Zimmermann2, Z. P. Demko2, S. Moshkevich2, P. R. Billings2, M. M. Sarwal1

    1University of California San Francisco, San Francisco, CA, 2Natera Inc., San Carlos, CA

    *Purpose: Plasma donor-derived cell-free DNA (dd-cfDNA) is a proven marker for allograft rejection in patients with kidney transplant (KT). Our goal was to assess performance…
  • 2019 American Transplant Congress

    Comparison Of Estimating Glomerular Filtration Equations In Living Kidney Donor Candidates Prior To Donation

    S. Hebert1, J. Xu2, H. Ibrahim1

    1Nephrology, Hypertension and Transplantation, Houston Methodist Hospital, Houston, TX, 2Houston Methodist Research Institute, Houston, TX

    *Purpose: Serum creatinine-based estimated glomerular filtration rate (eGFR) models have been shown to over- or underestimate measured iohexol GFR (mGFR), but it is unclear if…
  • 2019 American Transplant Congress

    The Combination of 3-Month Estimated Glomerular Filtration Rate and Proteinuria is a Valuable Tool for Evaluating Long-Term Kidney Graft Survival

    C. Mottola1, N. Girerd2, K. Duarte3, A. Aarnink4, M. Kessler5, L. Frimat6, S. Girerd6

    1Nephrology and Kidney Transplant Unit, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 2Clinical Investigation Center 1433, INSERM U1116, INI-CRCT, F-CRIN, Lorraine University, Vandoeuvre-lès-Nancy, France, 3Clinical Investigation Center 1433, INSERM 1116, INI-CRCT, F-CRIN, Lorraine Univeristy, Vandoeuvre-lès-Nancy, France, 4Laboratoire d’Histocompatibilité, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 5Nephrology and kidney transplant unit, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 6Nephrology and kidney transplant unit, INI-CRCT, F-CRIN, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France

    *Purpose: Estimated glomerular filtration rate (eGFR) measured at 1 year is the usual outcome used to predict the long-term graft survival in the field of…
  • 2019 American Transplant Congress

    Does Proton Pump Inhibitor Use Affect Renal Function in Kidney Transplant Recipients?

    K. Schütte-Nütgen1, D. J. Flothow1, B. Suwelack1, R. Schmidt2, H. Pavenstädt1, S. Reuter1

    1Department of Internal Medicine D, University Hospital Münster, Münster, Germany, 2Institute of Biostatistics and Clinical Research, University Hospital Münster, Münster, Germany

    *Purpose: Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. In the setting of renal transplantation, it…
  • 2019 American Transplant Congress

    Subclinical Rejection by Biopsy or Gene Expression Profile Predicts Long Term Kidney Function in Patients in the CTOT08 Trial

    R. Heilman1, D. Taber2, K. Guo3, S. Brietigam3, j. charette3, S. Kurian4, M. Abecassis3, J. Friedewald3

    1Mayo Clinic AZ, Scottsdale, AZ, 2MUSC, Charleston, SC, 3Northwestern University, Chicago, IL, 4Scripps, La Jolla, CA

    *Purpose: The CTOT08 trial showed that either histological subAR or positive gene expression profile (GEP) in the blood associated with histological subAR correlated with a…
  • 2019 American Transplant Congress

    The Association of Estimated Glomerular Filtration Rate at One Year Post-Kidney Transplant with Graft Loss is Not Modified by Delayed Graft Function

    J. Gill, M. Kadatz, J. Gill

    University of British Columbia, Vancouver, BC, Canada

    *Purpose: In kidney transplant recipients, eGFR at 1 year post-transplant has been shown to be associated with graft loss, but it is unclear if this…
  • 2018 American Transplant Congress

    Ischemia Reperfusion Injury & Risk for Antibody Mediated Rejection (ABMR) in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH)

    A. Vo,1 O. Aubert,2 J. Choi,1 N. Ammerman,1 H. Edmund,1 A. Peng,1 R. Najjar,1 S. Supreet,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; 2Paris Translational Research for Organ Transplantation, Necker Hospital, Paris, France.

    Introduction: Ischemia reperfusion injury (IRI) contributes to delayed graft function (DGF). IRI/DGF in HLA-sensitized (HS) patients likely activates innate and memory injury pathways that may…
  • 2018 American Transplant Congress

    Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study

    M. Matignon,1 C. Dudreuilh,1 P. Rémy,1 D. Desvaux,2 P. Grimbert.1

    1Nephrology Transplantation, APHP Henri Mondor, Creteil, France; 2Pathology, APHP Henri Mondor, Creteil, France.

    IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
  • 2018 American Transplant Congress

    Estimated GFR at Donor Screening and Achieved Measured GFR after Living Kidney Donation

    M. van Londen, J. van der Weijden, S. Bakker, S. Berger, J. Sanders, G. Navis, M. de Borst.

    Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands.

    Study Purpose: Accurate pre-donation renal function estimation is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies…
  • 2018 American Transplant Congress

    Effects of the Addition of Mycophenolate Mofetil on Renal Outcomes in Liver Transplant Recipients: A Single Center Review

    M. Henry, M. Vacha.

    Nebraska Medicine, Omaha, NE.

    Purpose: To evaluate the use of mycophenolate mofetil (MMF) and its effects on renal outcomes in liver transplant recipientsMethods: Adult liver transplant recipients from September…
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