2017 American Transplant Congress
FOXP3 rs3761548 A/C+A/A Genotype Is a Risk Factor for Steroid Resistant Rejection After Liver Transplantation.
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
(Introduction) Previous studies found that preferential accumulation of regulatory T (Treg) cells in the liver allografts during acute cellular rejection (ACR) was associated with less…2017 American Transplant Congress
Single Nuclear Polymorphisms of Complement Component 4 and Component 5 in Renal Transplant Recipients with Antibody-Mediated Rejection.
Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Background: Antibody-mediated rejection (ABMR) is an important cause of allograft dysfunction in short-term and long-term period. The complement component 4 (C4) and component 5 (C5)…2017 American Transplant Congress
Genome-Wide Genotyping in > 1500 Liver Allograft Recipient and Donor Pairs Reveals Several Associations with Acute Cellular Rejection.
Introduction:Despite higher survival rates of liver allograft recipients through improvements in post-transplant surgery treatments, acute cellular rejection (ACR) remains a frequent & significant complication impacting…2016 American Transplant Congress
A Genome Wide Association Study of New Onset Diabetes After Transplant in Kidney Transplantation.
Purpose: New-onset diabetes after transplantation (NODAT) is associated increased mortality. Using a DNA biobank linked to electronic medical records (EMR) at Vanderbilt University (BioVU), we…2016 American Transplant Congress
Association of Genetic Polymorphisms in Complement Independent Pathways with Donor Specific Antibodies in Kidney Allograft Recipients.
Background: It is known that detection of donor specific antibodies (DSA) is associated with antibody mediated rejection (AMR) and poor allograft outcomes. DSA mediates graft…2016 American Transplant Congress
Differences in Tacrolimus Troughs and Doses Between Caucasians and African Americans with Two CYP3A5 Loss-of-Function Alleles: Looking Beyond CYP3A5 Expression.
Higher tacrolimus (TAC) dose requirements and lower TAC troughs (TT) in African Americans (AA) relative to Caucasians (CA) have been presumed to be due to…2016 American Transplant Congress
Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.
Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…2016 American Transplant Congress
Significant Association of Innate Immune Related Genes Polymorphism on Infectious Complications Following Early Post Renal Transplantation phase.
Department of Gastroenrological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
ObjectiveInfectious complication is the leading cause of graft dysfunction and patient loss after renal transplantation (RT). In the early post-transplant phase where acquired immunity is…2016 American Transplant Congress
Association of Genetic Polymorphisms of Angiopoietin-Like 4 with Proteinuria in Kidney Allograft Recipients.
Background: Proteinuria is a hallmark of glomerular injury, and persistent proteinuria is associated with graft failure in kidney transplant patients. Recently, it is known that…2016 American Transplant Congress
High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients.
1UofMN, Mpls; 2MMRF, Mpls; 3HCMC, Mpls; 4UAB, Birmingham.
Kidney tx recipients carry a high burden of comorbidities, and some of the medications for these conditions have genetic predictors of efficacy and toxicity. These…
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