2017 American Transplant Congress
α-Lipoc Acid Improve the Short Term Outcomes in Human Liver Transplantation.
In liver transplantation (LT) the postreperfusion syndrome (PRS) is a serious intraoperative complication. The effect of α-lipoic acid (ALA) has not been evaluated. A double…2017 American Transplant Congress
Pre-Transplant Recipient Transcriptomic Profile May Predict Delayed Graft Function (DGF) in Kidney Transplantation.
Background: DGF is associated with a reduced long-term graft survival. Ischemia-reperfusion damage and donors' features have been always considered as key pathogenic factors in this…2017 American Transplant Congress
A Non-Invasive Urinary Common Rejection Module (uCRM) Gene Expression Score Quantifies and Differentiates Kidney Transplant Injury.
1University of California San Francisco, San Francisco; 2Immucor Inc, Atlanta
We sought to investigate the use of the common rejection module (CRM) genes in the discrimination of AR, BKVN, and stable transplant phenotypes in urine…2017 American Transplant Congress
A Study on Gene Expression of the Protective Effect of Nitric Oxide Releasing Nanofiber in Rat Renal Ischemia-Reperfusion Injury.
1Kyung Hee University, Seoul, Korea; 2Kwanwoon University, Seoul, Korea
Objective: Renal ischemia-reperfusion injury (IRI) is very important issue in kidney transplantation. Nitric oxide (NO) was well known to be a protector of IRI. The…2017 American Transplant Congress
Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome Appearance After Lung Transplantation.
Bronchiolitis obliterans syndrome (BOS) is the main manifestation of chronic lung allograft dysfunction responsible for the poor long-term outcome after lung transplantation. While physiopathological mechanisms…2017 American Transplant Congress
The Molecular Phenotypes of Rejection in Kidney Transplant Biopsies.
University of Alberta, Edmonton, AB, Canada
In a microarray analysis of 1208 kidney transplant indication biopsies, each biopsy was assigned molecular scores for seven phenotypes related to various aspects of TCMR,…2017 American Transplant Congress
Donor Genetic Background Determines the Severity of Delayed Graft Function Following Kidney Transplantation in Mice.
Background: Delayed graft function (DGF) has been associated with poor clinical transplant outcomes. Current mouse models of kidney transplant or acute kidney injury induced by…2017 American Transplant Congress
Assessment of C4d Positive Biopsies with No Histological Evidence of Inflammation Using Nanostring nCounter Technology.
Deposition of C4d has been an established part of the Banff classification scheme for antibody mediated rejection (AbMR) since 2001. More recently, C4d negative AbMR…2017 American Transplant Congress
The Natural History of Kidney Rejection: How Do Molecular Disease States Change Over Time in Patients with Repeat Indication Biopsies?
University of Alberta, Edmonton, AB, Canada
Molecular phenotypes are highly reproducible, but how do they evolve over time? In an unsupervised microarray analysis, 1208 kidney transplant biopsies were assigned to one…2017 American Transplant Congress
A New and Potent Distal Enhancer of the IL2 Gene.
Interleukin-2 is a potent T cell growth factor with crucial roles in both immunity and tolerance. Genetic studies in humans and mice demonstrate a role…
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