Articles tagged "Fibrosis"

2015 American Transplant Congress
Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients
J. Bank,¹ M. Reinders,¹ M. Mallat,¹ N. Schlagwein,¹ S. van der Kooij,¹ D. van Gijlswijk,¹ I. Bajema,² C. van Kooten,¹ H. de Fijter.¹
¹Nephrology, LUMC, Leiden, Netherlands; ²Pathology, LUMC, Leiden, Netherlands.
Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…
2015 American Transplant Congress
The Effects of Periostin on Renal Fibrosis After Ischemia-Reperfusion Injury Via p38 MAPK Pathway
J. An,^1,2 S. Yang,³ J. Hwang,⁴ J. Kim,¹ S. Kim,^2,5 C. Lim,^1,2 Y. Oh,^1,2 Y. Kim,² J. Lee.^1,2
¹Seoul National University Boramae Medical Center, Seoul, Republic of Korea; ²Seoul National University Hospital, Seoul, Republic of Korea; ³Seoul National University Kidney Research Institute, Seoul, Republic of Korea; ⁴Chung-Ang University Hospital, Seoul, Republic of Korea; ⁵Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ischemia-reperfusion injury during the transplantation procedure is associated with poor long-term allograft outcomes, such as rejection and fibrosis. Periostin, a matricellular protein, has been reported…
2015 American Transplant Congress
Role of Complement in Mediating Pericyte Trans-Differentiation in Resident Myofibroblasts: A New Hypothesis On Vascular Rarefaction in Renal Ischemia/Reperfusion (I/R) Injury
G. Castellano,¹ R. Franzin,¹ C. Divella,¹ A. Stasi,¹ A. Intini,¹ M. Gigante,¹ G. Lucarelli,¹ P. Ditonno,¹ M. Battaglia,¹ A. Crovace,¹ F. Staffieri,¹ G. Pertosa,¹ B. Oortwijn,² E. Amersfoort,² G. Grandaliano,³ L. Gesualdo.¹
¹University of Bari, Bari, Italy; ²Pharming Technologies NV, Leiden, Netherlands; ³University of Foggia, Foggia, Italy.
Vascular rarefaction is critical in the development of renal fibrosis. Pericytes regulate renal blood flow and might be an important source of renal interstitial myofibroblasts;…
2015 American Transplant Congress
Increased Fibroblast Growth Factor 21 Levels in Biliary Atresia Patients
D. Li, T. Lu, Y. Shan, C. Shen, X. Hua, M. Zhang, Q. Xia.
Renji Hospital, Shanghai, China.
Background: Fibroblast growth factor (FGF)-21, a hormone predominantly secreted by the liver, has recently been reported as a key circulating adipokine involving in metabolic disorders…