ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Endothelial activation"

  • 2016 American Transplant Congress

    The Role of HLA Class II Antibody in Endothelial Cell Activation and Allograft Rejection.

    G. Cantanhede,1 V. Carter,2 K. Giles,2 J. Kirby,1 S. Ali.1

    1Institute of Cellular Medicine, University of Newcastle, Newcastle, Tyne and Wear, United Kingdom; 2Histocompatibility and Immunogenetics, National Health Service Blood and Transplant, Newcastle, Tyne and Wear, United Kingdom.

    Background: Antibody-mediated rejection is one of the major causes of chronic rejection. This is mediated by endothelial cell activation, a process of endothelium microvascular inflammation…
  • 2016 American Transplant Congress

    Levels of VEGF-C, PLGF and Follistatin at 12 Months Post Transplantation Are Associated with Increased Risk for Long Term Progressive Renal Dysfunction.

    G. Dreyer,1 J. de Fijter,1 D. Briscoe,2 K. Daly,2 M. Reinders.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Transplantation Research Center, Boston Children's Hospital, Boston, MA.

    *contributed equallyIntroduction Integrity of the microvasculature is critical for long term survival after solid organ transplantation. We hypothesize that biomarkers of endothelial injury and repair…
  • 2015 American Transplant Congress

    Serum Proteins Are Significantly Upregulated in Patients With Clinical Antibody-Mediated Rejection

    A. Gareau,1 I. Gibson,2 C. Wiebe,1 J. Ho,1 D. Rush,1 P. Nickerson.1

    1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Pathology, University of Manitoba, Winnipeg, MB, Canada.

    Background: Antibody-mediated rejection (ABMR) is a major pathway associated with late graft loss. Although serum de novo donor-specific HLA antibodies are frequently observed in ABMR,…
  • 2015 American Transplant Congress

    Antibody-Induced Platelet Activation Increases Allograft Hyaluronan Fragmentation

    H.-H. Kuo,1 R. Fan,1 N. Dvorina,1 C. De La Motte,2 W. Baldwin.1

    1Immunology, Lerner Research Istitute, Cleveland, OH; 2Pathobiology, Lerner Research Institute, Cleveland, OH.

    Antibodies to MHC class I antigens have been shown to activate endothelial cells to release von Willebrand factor (vWf) and P-selectin from storage granules. These…
  • 2015 American Transplant Congress

    mTOR Inhibitors Reduce the Endothelial Transmigration of Leukocytes After Ischemia

    I. Werner, A. Hernandez-Sierra, F. Guo, A. Moritz, A. Beiras-Fernandez.

    Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany.

    ObjectivemTOR inhibitors Everolimus and Sirolimus are currently used as maintenance immunosuppressive agents to prevent rejection of solid transplanted organs. Episodes of transplant rejection and graft…
  • 2015 American Transplant Congress

    A Specific Inhibitor of C1s, TNT003, Prevents Complement-Mediated Enhancement of Monocyte Adhesion to Endothelium in Response to HLA Antibodies

    N. Valenzuela,1 K. Thomas,1 A. Mulder,2 G. Parry,3 S. Parker,3 E. Reed.1

    1Immunogenetics Center, UCLA, Los Angeles, CA; 2Leiden University, Leiden, Netherlands; 3True North Therapeutics, San Francisco, CA.

    HLA antibody (Ab) mediated complement activation on endothelial cells (EC) is likely a critical driver of antibody-mediated inflammation. Production of complement anaphylatoxins by HLA antibodies…
  • 2015 American Transplant Congress

    Oxidative Stress During Organ Recovery Influences Transplant Vasculopathy Development

    M. Maglione,1 G. Riede,1 B. Cardini,1 D. Bernhard,2 B. Messner,2 K. Watschinger,3 C. Steger,4 G. Brandacher,5 J. Pratschke,1 E. Werner,3 R. Oberhuber.1

    1Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria; 2Cardiac Surgery Research Laboratory, Department of Surgery, Vienna Medical University, Vienna, Austria; 3Division of Biological Chemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria; 4Institute of Pathology, Innsbruck Medical University, Innsbruck, Austria; 5Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

    Transplant vasculopathy is still a major obstacle to long-term graft survival. Pharmacological strategies aiming at preventing it are still lacking. Herein we show that the…
  • « Previous Page
  • 1
  • …
  • 3
  • 4
  • 5

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2022 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use