Articles tagged "Efficacy"

2021 American Transplant Congress
Rabbit Anti-thymocyte Globulin Induction Dosing Strategies in a High-risk Kidney Transplant Population
C. Nguyen, R. Yau, C. Tunwar
Pharmacy, CHI Baylor St. Luke's Medical Center, Houston, TX
*Purpose: The objective of this retrospective observational study is to compare the safety and efficacy of two dosing strategies, rabbit anti-thymocyte globulin (rATG) at a…
2021 American Transplant Congress
Outcomes in Standard vs. Extended Use of Thymoglobulin as Induction Therapy in Kidney Transplant Recipients
N. M. Sifontis¹, A. Coleman¹, D. Tang¹, K. Lau², S. Karhadkar², A. DiCarlo², A. Diamond²
¹Temple University School of Pharmacy, Philadelphia, PA, ²Temple University Health System, Philadelphia, PA
*Purpose: Thymoglobulin induction along with modern maintenance immunosuppression has been found to have a significant reduction in acute rejection in kidney transplantation. The recommended duration…
2021 American Transplant Congress
Evaluation of Safety and Efficacy of PCSK9 Inhibitors in Solid Organ Transplant Recipients: Experience at a Large Multi-organ Transplant Center
A. Ucci¹, M. Norris², J. Trofe-Clark², T. Fallah², M. Meck¹, R. Samudralwar¹, M. V. Genuardi³
¹Hospital of Univ of Pennsylvania, Philadelphia, PA, ²Penn Transplant Institute, Hospital of Univ of Pennsylvania, Philadelphia, PA, ³Cardiovascular Medicine Div, Hospital of Univ of Pennsylvania, Philadelphia, PA
*Purpose: The aim of the study was to characterize the efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in solid organ transplant…
2020 American Transplant Congress
The Learning Curve for Pure Laparoscopic Robotic Kidney Transplantation: An Analysis of Outcomes of the First 80 Consecutive Cases at a High-Volume Transplant Center
F. Tinney Jr.¹, J. Stracke², T. Ivanics¹, A. Elsabbagh¹, J. Denny¹, D. Kim¹, L. Malinzak¹, A. Yoshida¹
¹Transplant Institute, Henry ford Hospital, Detroit, MI, ²Transplant Surgery, Metro Health Hospital, Wyoming, MI
*Purpose: Robotic surgery is increasingly used in complex operations, including living-donor kidney transplantation. At this time, knowledge of the number of cases required to attain…
2020 American Transplant Congress
A Long-Term Follow-Up Study of High-Dose Intravenous Cyclosporine Combined Plasma Exchange in the Treatment of FSGS Recurrence after Renal Transplantation – A Single Center Clinical Experience
Y. Cui, M. F. Wang, C. C. Wei, J. Y. Wu
Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
*Purpose: There was still lack of effective treatment for focal segmental glomerulosclerosis(FSGS)recurrence after renal transplantation. The purpose of this study was to explore the risk…
2020 American Transplant Congress
The Efficacy and Safety of Ischemia-Free Liver Transplantation (IFLT) in the Treatment of End-Stage Liver Disease in a Prospective, Randomized, Controlled Trial: A Report of the First 25 Cases
X. He, Z. Guo, Q. Zhao, C. Huang, W. Ju, D. Wang, M. Chen, L. Wu, Y. Ma, Y. Chen, A. Hu, X. Zhu
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: We’ve established a novel procedure called ischemia-free liver transplantation (IFLT). The results from the pilot study suggest that IFLT might prevent ischemia-reperfusion injury (IRI)…
2020 American Transplant Congress
A Video Education Intervention to Improve Kidney Transplant Knowledge and Willingness to Complete Transplant Evaluation in Dialysis Patients
D. A. DuBay¹, T. A. Morinelli¹, Z. Sutton¹, M. Chastain¹, T. Thompkins Tindal¹, Z. Su², E. Weeda³, P. Mauldin⁴, M. Casey¹, J. Bian², D. Taber¹, P. K. Baliga¹
¹Surgery, Division of Transplant Surgery, Medical University of South Carolina`, Charleston, SC, ²General Internal Medicine, Medical University of South Carolina`, Charleston, SC, ³Clinical Pharmacy-Outcomes Sciences, Medical University of South Carolina`, Charleston, SC, ⁴General Internal Medicine, Medical University of South Carolina, Charleston, SC
*Purpose: The Centers for Medicare and Medicaid Services has set a goal of 30% (currently 18.5%) of dialysis patients to be on a transplant (Tx)…
2020 American Transplant Congress
Thymoglobulin for Induction Less is Clearly More!
N. Patel, P. Nicole
-, -, SC
*Purpose: The ideal total dose of anti-thymocyte globulin (ATG) is unknown in the African American (AA) kidney transplant population.The purpose of this study was to…
2020 American Transplant Congress
Effect of Therapeutic Plasma Exchange on Glomerular Filtration Rate in Patients with Acute Humoral Rejection
M. Maza Moreno, S. Hernandez-Estrada, J. Cano Cervantes, D. Maldonado Tapia, M. Alamilla Sanchez
Nephrology and Transplant Division, CMN 20 de Noviembre, Ciudad de Mexico, Mexico
*Purpose: AMR is the main risk factor for graft loss, especially after the first post transplant year. Up to 80% of patients achieve response with…
2020 American Transplant Congress
Assessment of Time to Therapeutic Tacrolimus Levels Following Renal Transplantation in a Non-Weight-Based Dosing Model
J. Banbury¹, A. Dodson¹, C. Lin², K. Gutierrez¹
¹University of Alabama at Birmingham Hospital, Birmingham, AL, ²Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL
*Purpose: The optimal initial dose for tacrolimus (TAC) after renal transplant (RT) remains controversial with limited evidence comparing weight-based and conservative strategies. Recent literature suggests…