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American Transplant Congress abstracts

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Articles tagged "Drug interaction"

  • 2021 American Transplant Congress

    Implementation of a High-risk Medication Report for Waitlisted Liver Transplant Candidates

    M. M. Eiting1, H. Yeh2, M. Cote1, S. Shao1, A. B. Scherrer2, L. Dageforde2, N. Elias2, C. Rogers Marks1

    1Pharmacy, Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, MA

    *Purpose: Use of high-risk medications (HRMs) at the time of liver transplant may lead to delays in surgery or peri-operative complications (bleeding, drug-drug interactions (DDI),…
  • 2021 American Transplant Congress

    Pilot Evaluation of Prognosis After Liver Transplantation in Patients with a History of Hepatocellular Carcinoma and Pd-1 Inhibition

    M. Chen1, Z. Chen1, X. Lin2

    1First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2the Eastern Hospital of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: The successful applications of programmed death protein-1 (PD-1) inhibitors in cancer therapy has led to an expanding use of immunotherapy in oncolog Liver transplantation…
  • 2021 American Transplant Congress

    A Retrospective Analysis of the Safety and Efficacy of Apixaban After Lung Transplant

    T. Sam1, K. Reininger2, R. Patel1, C. Naik1, K. Ausloos1, R. Rosenblatt1, T. Grazia1, I. Lam3

    1Transplant, Baylor University Medical Center, Dallas, TX, 2Transplant, Hennepin County Medical Center, Minneapolis, MN, 3Transplant, Sharp Memorial Hospital, San Diego, CA

    *Purpose: Atrial arrhythmias and venous thromboembolism (VTE) are common after lung transplant. While direct acting oral anticoagulants (DOACs) have become anticoagulants of choice in atrial…
  • 2020 American Transplant Congress

    Sodium Zirconium Cyclosilicate Use in Solid Organ Transplant Recipients and its Effect on Potassium and Immunosuppression

    R. Winstead, M. Demehin, I. Yakubu, C. Song, A. Brown, M. Levy, L. Kamal, G. Gupta

    VCU Health, Richmond, VA

    *Purpose: Transplant recipients often suffer from hyperkalemia which can limit pharmacotherapy. The cause of hyperkalemia is often multifactorial including kidney dysfunction, calcineurin inhibitor use, and…
  • 2020 American Transplant Congress

    Zoledronate Induced AKI with Nephrotic Range Proteinuria in a Transplant Kidney

    S. Reddy, H. Khamash

    Nephrology, Mayo Clinic, Phoenix, AZ

    *Purpose: An unusual presentation of acute kidney injury with nephrotic range proteinuria following zoledronate in a normal functioning transplant kidney.*Methods: 61-year-old lady with history of…
  • 2020 American Transplant Congress

    Largest Experience of Safety, and Efficacy of Patiromer in Solid Organ Transplants (SOT)

    P. Singh1, H. Winters2, T. E. Pesavento1, K. Schnelle2

    1Transplant Nephrology, Ohio State University, Columbus, OH, 2Transplant Pharmacy, Ohio State University, Columbus, OH

    *Purpose: Hyperkalemia, a potentially life‐threatening electrolyte abnormality, is commonly seen SOT. The predisposing factors are renal-dysfunction, and medications (CNI, TMP-SMX, ACEI, and ARBs). Patiromer, a…
  • 2020 American Transplant Congress

    Role of Tacrolimus Dose Adjustment at Discontinuation of Fluconazole in Liver Transplant

    J. Yau, H. Morris

    University of Virginia Health System, Charlottesville, VA

    *Purpose: The purpose of this study was to characterize the effects of fluconazole (fluc) discontinuation on tacrolimus (tac) levels and the role of prophylactic dose…
  • 2020 American Transplant Congress

    Lack of Drug-Drug Interaction between Maribavir and Voriconazole

    I. H. Song1, K. Ilic2, J. Wu3

    1Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, 2Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, 3Biostat, Shire, a Takeda Company, Lexington, MA

    *Purpose: Maribavir is being evaluated in Phase 3 trials for the treatment of cytomegalovirus infections in transplant recipients. These patients often take numerous concomitant medications,…
  • 2020 American Transplant Congress

    Evaluation of the Use of Sublingual Tacrolimus in the Inpatient Setting

    K. Szempruch1, L. Kemp1, A. Barber1, S. Mason1, G. Offei-Nkansah1, D. Gerber2, P. Owen1

    1Pharmacy, UNC Medical Center, Chapel Hill, NC, 2Surgery-Transplant, UNC Medical Center, Chapel Hill, NC

    *Purpose: To determine the efficacy and safety of sublingual (SL) tacrolimus (TAC) administration.*Methods: A single-center, retrospective study was performed on solid organ transplant recipients who…
  • 2020 American Transplant Congress

    Evaluation of SUBA-Itraconazole Use in Lung Transplant Recipients

    J. G. Youssef1, C. Ahmed1, B. J. Pierce2, C. Pham2, F. Ye1, K. Tatum1, S. Yau1, A. Goodarzi1, H. J. Huang1

    1Department of Medicine, Houston Methodist Hospital, Houston, TX, 2Department of Pharmacy, Houston Methodist Hospital, Houston, TX

    *Purpose: Itraconazole (IT) is commonly used after lung transplant for fungal prophylaxis, particularly in those with a history of skin cancer, concern for Histoplasmosis infection,…
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