2021 American Transplant Congress
A Retrospective Analysis of the Safety and Efficacy of Apixaban After Lung Transplant
*Purpose: Atrial arrhythmias and venous thromboembolism (VTE) are common after lung transplant. While direct acting oral anticoagulants (DOACs) have become anticoagulants of choice in atrial…2021 American Transplant Congress
Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant
Massachusetts General Hospital, Boston, MA
*Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…2021 American Transplant Congress
Evaluate the Effect of Cresemba (isavuconazonium Sulfate) Capsule and Noxafil (posaconazole) Delayed Release Tablets on Tacrolimus Dose to Concentration (D/C) Ratios in Lung Transplant Recipients
*Purpose: Evaluate the effect of Cresemba (isavuconazonium sulfate) capsule and Noxafil (posaconazole) delayed release tablet on tacrolimus dose to concentration (D/C) ratio in lung transplant.*Methods:…2020 American Transplant Congress
Largest Experience of Safety, and Efficacy of Patiromer in Solid Organ Transplants (SOT)
*Purpose: Hyperkalemia, a potentially life‐threatening electrolyte abnormality, is commonly seen SOT. The predisposing factors are renal-dysfunction, and medications (CNI, TMP-SMX, ACEI, and ARBs). Patiromer, a…2020 American Transplant Congress
Role of Tacrolimus Dose Adjustment at Discontinuation of Fluconazole in Liver Transplant
University of Virginia Health System, Charlottesville, VA
*Purpose: The purpose of this study was to characterize the effects of fluconazole (fluc) discontinuation on tacrolimus (tac) levels and the role of prophylactic dose…2020 American Transplant Congress
Lack of Drug-Drug Interaction between Maribavir and Voriconazole
*Purpose: Maribavir is being evaluated in Phase 3 trials for the treatment of cytomegalovirus infections in transplant recipients. These patients often take numerous concomitant medications,…2020 American Transplant Congress
Evaluation of the Use of Sublingual Tacrolimus in the Inpatient Setting
*Purpose: To determine the efficacy and safety of sublingual (SL) tacrolimus (TAC) administration.*Methods: A single-center, retrospective study was performed on solid organ transplant recipients who…2020 American Transplant Congress
Evaluation of SUBA-Itraconazole Use in Lung Transplant Recipients
*Purpose: Itraconazole (IT) is commonly used after lung transplant for fungal prophylaxis, particularly in those with a history of skin cancer, concern for Histoplasmosis infection,…2020 American Transplant Congress
Glecaprevir-Pibrentasvir Effect on Tacrolimus Troughs in Abdominal Transplant Recipients
The Ohio State Wexner Medical Center, Columbus, OH
*Purpose: Glecaprevir-pibrentasvir (GP) is one of several pangenotypic therapies available for the treatment of hepatitis C. Historical use of ritonavir based hepatitis C therapies increased…2020 American Transplant Congress
Sodium Zirconium Cyclosilicate Use in Solid Organ Transplant Recipients and its Effect on Potassium and Immunosuppression
*Purpose: Transplant recipients often suffer from hyperkalemia which can limit pharmacotherapy. The cause of hyperkalemia is often multifactorial including kidney dysfunction, calcineurin inhibitor use, and…
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