Articles tagged "Donors"

2015 American Transplant Congress
A Novel Tool to Evaluate Coercion, Pressure, and Motivation in Potential Live Kidney Donors
A. Shaffer,¹ E. King,¹ J. Kahn,² L. Erby,³ D. Segev.¹
¹Surgery, Johns Hopkins University, Baltimore, MD; ²Bergman Institute for Bioethics, Johns Hopkins University, Baltimore, MD; ³School of Public Health, Johns Hopkins University, Baltimore, MD.
Live donor kidney transplantation yields improved graft survival and recipient longevity, as compared to deceased donors. However, one concern with living donation is the potential…
2015 American Transplant Congress
Cultural Domains Affecting Organ Donation in Indian Country
T. Bongiovanni,^1,3,4 J. Rawlings,² J. Trompeta,³ M. Nunez-Smith.¹
¹Dept of Surgery, UCSF, San Francisco; ²Tribal Council, New Haven, CT; ³Robert Wood Johnson Foundation, Yale School of Medicine, New Haven, CT; ⁴Department of Veterans Affairs, West Haven.
Background: The prevalence of end-stage renal disease is 3.5 times greater among the >2.5 million Native Americans or Alaskan Natives (NAs) in the US than…
2015 American Transplant Congress
Ischemic Cholangiopathy Following Liver Transplantation from Donation After Circulatory Death Donors: Role of Tissue Plasminogen Activator Flush
C. Kubal,¹ R. Mangus,¹ J. Fridell,¹ M. Wingler,² S. Nagai,¹ B. Ekser,¹ J. Tector.¹
¹Department of Surgery, Indiana University, Indianapolis, IN; ²Indiana Organ Procurement Organization, Indianapolis, IN.
Background: Formation of microthrombi within the peribiliary arterial plexus causing necrosis of biliary epithelium may be responsible for ischemic cholangiopathy (IC) after donation after circulatory…
2015 American Transplant Congress
"In-House" Controlled Oxygenated Rewarming After Initial Static Cold Storage: First Clinical Application in Marginal Donor Livers
D. Hoyer,¹ Z. Mathé,¹ A. Gallinat,¹ A. Canbay,² J. Treckmann,¹ U. Rauen,³ A. Paul,¹ T. Minor.⁴
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany; ³Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; ⁴Surgical Research Division, University Hospital Bonn, Bonn, Germany.
IntroductionControlled oxygenated rewarming of cold stored livers by machine perfusion demonstrated a strong protective effect in preclinical studies. Here we report on the first clinical…
2015 American Transplant Congress
Delivery of Heme Oxygenase-1-Cell Penetrating Peptide (HO-1-CPP) Into Hepatocytes, Kupffer and Islet Cells in In Vitro and Ex Vivo Models of Cold Ischemia
A. Venkatachalam,¹ C. Wood,¹ Q. Hu,¹ I. Alwayn.²
¹Surgery, Dalhousie University, Halifax, NS, Canada; ²Surgery, Pathology, Microbiology & Immunology, Surgical Lead Multi Organ Transplant Program, QEII Health Sciences Center, Dalhousie University, Halifax, NS, Canada.
In an attempt to increase the number of donor organs available to transplantation extended criteria donor (ECD) organs are more frequently considered. Unfortunately, ECD organs…
2015 American Transplant Congress
Evaluation of Geographically Distant Living Kidney Donors: A Barrier to Living Donation?
F. Weng, N. Dhillon, L. Davis, R. Goldberg, A. Patel, K. Tibaldi, M. Morgievich, S. Mulgaonkar.
Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.
Introduction: Living kidney donors often live far from the recovering transplant center where they donate. We sought to determine (1) characteristics of these geographically distant,…
2015 American Transplant Congress
Causes of Poor Renal Function of Kidney Transplants from Uncontrolled Donation After Cardiac Death Donors (UDCDD)
M. Molina, E. González, E. Gutiérrez, E. Morales, E. Hernández, A. Sevillano, N. Polanco, J. Cabrera, M. Praga, A. Andres.
Nephrology, Hospital 12 de Octubre, Madrid, Spain.
INTRODUCTION: Kidneys grafts from UDCDD have higher ischemia injury. It develops in higher primary non function, lower graft survival and worst renal function compared to…
2015 American Transplant Congress
Prospective Measurement of Plasma Neutrophil Gelatinase-Associated Lipoprotein in Living Kidney Donors
Y. Yoon,¹ K. Choi,² D. Joo,³ K. Huh,³ M. Kim,³ S. Kim,³ Y. Kim,³ S. Yang,² W. Han.¹
¹Department of Urology, Yonsei University College of Medicine, Seoul, Korea; ²Department of Urology, CHA University, Seongnam-si, Korea; ³Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea.
Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for acute kidney injury. This study was conducted to determine the clinical implications of perioperative plasma NGAL…
2015 American Transplant Congress
Effect of Distinct Immunosuppressive Protocols On the Profile of Cytokines Expression in Renal Transplant Recipients of Extended Criteria Donor Kidneys
C. Montoro Mazeti,¹ C. Zangrossi Dezotti,¹ I. Fernandes-Charpiot,^1,2 H. Caldas,¹ M. Baptista,^1,2 M. Abbud Filho.^1,2,3
¹Laboratory of Immunology and Experimental Transplantation, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ²Department of Medicine, Division of Nephrology, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ³Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.
Background: Transplant recipients (RTx) of kidneys classified as extended criteria (ECD) seems to have worst outcomes when compared with RTx of standard kidneys (SCD) and…
2015 American Transplant Congress
Use of Tissue Plasminogen Activator (TPA) in Liver Transplantation from Donation After Cardiac Death (DCD) Donors: A Controlled Randomized Trial
B. Eghtesad, K. Hashimoto, M. Watson, M. Nazzal, C. Quintini, D. Kelly, T. Diago, N. Kawamura, G. El-Gazzaz, M. Fujiki, F. Aucejo, C. Winans, C. Miller, J. Fung.
Hepatobiliary and Liver Transplant Surgery, Cleveland Clinic, Cleveland, OH.
To further evaluate the impact of tPA in reduction of ITBS in livers recovered from the DCD donors we conducted a controlled randomized trial. Between…