Characteristics and Outcomes of Kidneys Procured from Donors With KDPI > 80%
TRIBE Consortium, New Haven, CT.
Meeting: 2015 American Transplant Congress
Abstract number: 47
Keywords: Cadaveric organs, Donors, Kidney, marginal, Outcome
Session Information
Session Name: Concurrent Session: Kidney Utilization/Center Issues
Session Type: Concurrent Session
Date: Sunday, May 3, 2015
Session Time: 2:15pm-3:45pm
Presentation Time: 3:27pm-3:39pm
Location: Room 121-AB
Kidneys procured from donors with KDPI>80% are often biopsied and pumped, yet frequently discarded. The accuracy of these quality assessment tools remain controversial but contribute heavily in terms of discard. Our objective was to compare characteristics and transplant outcomes of kidneys from 641 donors with KDPI>80%. Donors for whom at least one of the kidneys were discarded due to with technical issues were excluded. Donors were grouped by number of kidneys discarded: A) none (378, 59%), B) one (75, 12%) and C) both (188, 29%). The donors in group B and C were more likely to be older, hypertensive, diabetic and had higher terminal creatinine (p<0.05). Urinary levels of NGAL, KIM-1 and IL-18 obtained at procurement were not different between the groups. The kidneys of donors in group B and C were more frequently biopsied and less frequently to be pumped
Variable | A) 0 discarded (n=756) | B) 1 discarded (n=150) | C) 2 discarded (n=376) | p* |
Kidney biopsy | 593 (78%) | 130 (87%) | 329 (88%) | <0.001 |
Glomerulosclerosis >20% | 21 (3%) | 15 (11%) | 148 (44%) | <0.001 |
Pumped | 392 (52%) | 70 (47%) | 152 (40%) | <0.001 |
1 hr resistance | 0.27 (0.22,0.37) | 0.29 (0.25,0.46) | 0.35 (0.26,0.5) | <0.001 |
1 hr flow | 101 (79,122) | 97 (71,110) | 78 (56, 104) | <0.001 |
To cite this abstract in AMA style:
Doshi M, Hall I, Weng F, Schroppel B, Ficek J, Hasz R, Thiessen-Philbrook H, Formica R, Reese P, Parikh C. Characteristics and Outcomes of Kidneys Procured from Donors With KDPI > 80% [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/characteristics-and-outcomes-of-kidneys-procured-from-donors-with-kdpi-80/. Accessed December 4, 2024.« Back to 2015 American Transplant Congress