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Articles tagged "Cytomeglovirus"

  • 2015 American Transplant Congress

    Low Dose Valganciclovir Is an Effective Prophylaxis Against Cytomegalovirus in High Risk (Donor+/ Recipient-) Kidney Transplants Recipients

    S. Fayek,1 E. Beshears,1 N. Alvey,2 A. Sauer,1 R. Lieber,1 O. Olaitan,1 E. Hollinger,1 S. Jensik,1 J. Geyston,2 M. Brokhof,2 A. Hodowanec,3 D. Simon,3 M. Hertl.1

    1Surgery/Transplant, Rush University Medical Center, Chicago; 2Pharmacy, Rush University Medical Center, Chicago; 3Medicine/Infectious Diseases, Rush University Medical Center, Chicago.

    Introduction: Universal prophylaxis against Cytomegalovirus (CMV) disease is endorsed in high risk seronegative kidney (K) transplant (TX) recipients of organs from seropositive donors (D+/R-) using…
  • 2015 American Transplant Congress

    Preemptive Therapy for Cytomegalovirus Disease in Liver Transplant Recipients-A Single Center Experience

    N. Alvey,1 J. Tieman,1 A. Diamond,2 A. Hodowanec,1 D. Simon,1 S. Fayek,1 M. Hertl,1 O. Olaitan,1 E. Hollinger,1 E. Chan.1

    1Rush University Medical Center, Chicago, IL; 2Lahey Hospital and Medical Center, Boston, MA.

    Background: Cytomegalovirus (CMV) is a common opportunistic infection after liver transplantation and is associated with significant morbidity and mortality. There are two strategies for preventing…
  • 2015 American Transplant Congress

    Role of CMV, BKV, and Immunosupression Non-Adherence in Early and Late De Novo Donor Specific Anti-HLA Antibody Development and Outcomes

    M. Everly,1 L. Rebellato,2 K. Briley,2 A. Maldonado,3 P. Bolin,2 C. Haisch,2 W. Kendrick,4 S. Kendrick,4 C. Morgan,2 R. Harland,2 P. Terasaki.1

    1Terasaki Foundation, Los Angeles; 2East Carolina University, Greenville, NC; 3Vidant Medical Center, Greenville, NC; 4Eastern Nephrology Associates, Greenville, NC.

    This analysis aims to identify appropriate de novo DSA (dnDSA) screening points and delineate the post-transplant (txp) scenarios preceding dnDSA development to aid in clinical…
  • 2015 American Transplant Congress

    Low Dose Valganciclovir Prophylaxis Following Renal Transplantation With Steroid Free Immunosuppression

    J. Chen,1 A. Shah,2 M. Sauer,1 T. Taber,3 A. Sharfuddin,3 M. Yaqub,3 D. Mishler,3 J. Powelson,4 W. Goggins.4

    1Pharmacy, IU Health, Indianapolis; 2Surgery, Thomas Jefferson University, Philadelphia; 3Nephrology, Indiana University School of Medicine, Indianapolis; 4Surgery, Indiana University School of Medicine, Indianapolis.

    AST ID guidelines recommend a valganciclovir (VGCV) prophylaxis dose of 900 mg daily for patients with CrCL > 60 mL/min with reduced dose for renal…
  • 2015 American Transplant Congress

    Impact of Anti-CMV Prophylactic Therapy on the Development of CMV Quantiferon Sero-Conversion in High-Risk Patients

    A. Palanisamy, D. Taber, N. Pilch, C. Bratton, J. McGillicuddy, P. Baliga, K. Chavin.

    Transplant Surgery, Medical University of South Carolina, Charleston, SC.

    Body: Abdominal organ transplants at high risk for CMV infection (D+/R­) remain a difficult cohort to prevent late CMV infection despite prolonged valganciclovir (VGC) administration.…
  • 2015 American Transplant Congress

    Does Prophylaxis Strategy Matter? CMV Reactivation in Moderate Risk (R+) Heart Transplant Recipients

    E. Liu, C. Doligalski.

    Pharmacy, Tampa General Hospital, Tampa, FL.

    Purpose: CMV is a significant complication in heart transplant recipients (HTR). Little evidence exists to guide prophylaxis in moderate risk (R+) patients.Methods: An IRB-approved review…
  • 2015 American Transplant Congress

    Invasive CMV-Infection of the Duodenal Cuff – An Underestimated Entity of CMV Infection and Its Potential Impact On Outcome After Pancreas Transplantation

    A. Biglarnia,1 B. von Zur-Mühlen,1 S. Yamamoto,1 D. Berglund,1 M. Wagner,2 A. Sedigh,1 G. Tufveson,1 E. Larsson,3 F. Sund.2

    1Transplantation, Surgical Sciences, Uppsala, Sweden; 2Medical Scinces, Upsala, Sweden; 3Genetics and Pathology, Uppsala, Sweden.

    IntroductionWe present data on the incidence of focal invasive CMV-infection of the duodenal cuff and its potential impact on clinical outcome after pancreas transplantation (PT).Material…
  • 2015 American Transplant Congress

    The Impact of Administrating Everolimus Before Cytomegalovirus Infection to Prevent CMV Recurrence in Heart Transplant Recipients

    M. Ishida, K. Toda, T. Nakamura, S. Miyagawa, Y. Yoshikawa, S. Fukushima, S. Saito, D. Yoshioka, K. Kubota, T. Ueno, T. Kuratani, Y. Sawa.

    Cardiovascular Surgery, Osaka University, Suita, Osaka, Japan.

    Purpose – Cytomegalovirus (CMV) infection is a major complication in heart transplant recipients. Recent trials indicate that the use of the mammalian target of rapamycin…
  • 2015 American Transplant Congress

    Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 T. Sandes- Freitas,1 N. Oliveira,1 W. Aguiar,2 G. Bassos,1 M. Franco,3 M. Gerbase- Lima,4 E. Campos,4 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil; 4Immunogenetic, AFIP, Sao Paulo, Brazil.

    BACKGROUND: CMV infection is associated with inferior long-term kidney transplant outcomes. This study compared the incidence of CMV infection/disease in de novo kidney transplant recipients…
  • 2015 American Transplant Congress

    Preventing Cytomegalovirus Infection in Intermediate-High Risk Liver Transplant Recipients: Acyclovir Vs Valganciclovir

    S. Dulanya, A. Anamisis, D. Tsapepas.

    Department of Pharmacy, New York Presbyterian Hospital, New York City, NY.

    Cytomegalovirus (CMV) is an opportunistic infection responsible for profound morbidity and mortality among solid organ transplant recipients. A donor and recipient's CMV IgG serostatus influences…
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