ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Bone marrow transplantation"

  • 2015 American Transplant Congress

    Kidney Transplantation After Hematopoietic Cell Transplantation in Plasma Cell Dyscrasias

    V. Domínguez-Pimentel,1 F. Fortich-Barrios,1 O. Siverio-Morales,1 E. Martín-Izquierdo,1 A. Jarque-López,1 N. Del Castillo-Rodríguez,1 J. García,1 P. Ríos,2 M. Macía.1

    1Division of Nephrology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain; 2Division of Hematology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.

    INTRODUCTION:The plasma cell dyscrasias (PCD) include a number of entities such as multiple myeloma (MM), primary amyloidosis (AL) and Monoclonal immunoglobulin deposition disease (MIDD). Hematopoietic…
  • 2015 American Transplant Congress

    Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation

    G. Torregrossa,1 M. Sosin,2 G. Gerosa,3 A. Dorafshar.2

    1Cardiothoracic Surgery, Mount Sinai Hospital, NYC, NY; 2Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD; 3Cardiac Surgery, Universita'di Padova, Padova, Italy.

    Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…
  • 2015 American Transplant Congress

    ALDH Expression in Facilitating Cells Plays a Critical Role in Regulatory T Cell Induction and GVHD Prevention

    H. Xu,1 T. Miller,1 Y. Huang,1 S. Ildstad.1,2

    1Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; 2Regenerex, LLC, Louisville, KY.

    Graft-vs-host disease (GVHD) is a major source of morbidity in hematopoietic stem cell transplantation (HSCT), limiting its application to treat nonmalignant hematopoietic diseases and to…
  • 2015 American Transplant Congress

    Vascularized Bone Marrow Plays a Critical Role in Inducing Tolerance of Osteomyocutaneous Allografts

    C.-H. Lin,1 M. Anggelia,1 Y.-L. Wang,1 H.-Y. Cheng,1 W. Lee,2 G. Brandacher.2

    1Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taipei, Taiwan; 2Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.

    Background: Vascularized composite allograft (VCA) that includes medullary bone may provide proposed benefits ofvascularized bone marrow transplantation (VBMT), such as a continuous supply of donor…
  • 2015 American Transplant Congress

    Recipient IL-33 Promotes Type 1 Alloimmunity and Lethal Acute GVHD Following alloHCT

    B. Matta,1 D. Reichenbach,2 V. Schwarze,3 V. Tkachev,4 L. Mathews,1 Q. Liu,1 M. Warncke,5 J. Ferrara,4 R. Zeiser,3 B. Blazar,2 H. Turnquist.1

    1Surgery, Univ. of Pittsburgh, Pittsburgh, PA; 2Pediatrics, Univ. of Minnesota, Minneapolis, MN; 3Hematology and Oncology, Univ. Medical Center Freiburg, Freiburg, Germany; 4Pediatrics, Univ. of Michigan, Ann Arbor, MI; 5Novartis Institute for Biomedical Research, Basel, Switzerland.

    Background: Graft-versus-host disease (GVHD) is a common complication of allogeneic (allo) hematopoietic cell transplantation (HCT) that limits its widespread application for the induction of transplant…
  • 2015 American Transplant Congress

    Donor Specific Tolerance Can Be Induced by Donor Bone Marrow Transfer With Activation of Invariant Naturel Killer T Cells

    S. Miyairi,1 T. Hirai,1 R. Shibahara,1 K. Omoto,1 S. Nunoda,2 K. Yamazaki,2 Y. Ishii,3 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; 2Cardiovascular Surgery, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; 3Laboratory of Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.

    It has been reported that liposomal formulation of a-galactosylceramide(lipo-aGC) could induce antigen specific regulatory T cells (Treg) in vivo when administered with particular antigens. We…
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