ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Bone marrow transplantation"

  • 2016 American Transplant Congress

    Three-Year Outcome After HSCT with Subsequent KT from the Same Haploidentical Donor without Immunosuppression.

    C. Schwarz,1 A. Lawitschka,2 G. Böhmig,3 E. Dauber,4 H. Greinix,5 N. Kozakowski,6 F. Mühlbacher,1 G. Berlakovich,1 T. Wekerle.7

    1Dept. of Surgery, Div. of Transplantation, Medeical University of Vienna, Vienna, Austria; 2St. Anna Children's Hospital, Vienna, Austria; 3Dept. of Internal Medicine, Division of Nephrology, Medical University of Vienna, Vienna, Austria; 4Dept. of Transfusion Medicine, Medical University of Vienna, Vienna, Austria; 5Dept of Internal Medicine, Div of Hematology, Medical University of Graz, Graz, Austria; 6Dept. of Clinical Pathology, Medical University of Vienna, Vienna, Austria; 7Section of Transplantation Immunology, Dept. of Surgery, Medical University of Vienna, Vienna, Austria.

    Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to donor-specific tolerance. Patients reported in the literature that underwent kidney transplantation (KT) after a previous HSCT…
  • 2016 American Transplant Congress

    Nontuberculous Mycobacterial Infection Among Allogeneic Hematopoietic Stem Cell Transplant Recipients: A 16-Year Cohort Study.

    A. Alghamdi, J. Lipton, C. Rotstein, D. Kumar, A. Humar, T. Mazzulli, S. Husain.

    University Health Network, Toronto, Canada.

    Background: Nontuberculous mycobacteria (NTM) infections in hematopoietic stem cell transplant (HSCT) recipients can be associated with significant morbidity and mortality.Methods: We identified all allogeneic HSCT…
  • 2016 American Transplant Congress

    Hematopoietic Cell Transplant and Solid Organ Transplantation: A First Report of the U.S. Experience.

    M. Gupta, M. Levine, P. Abt.

    Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA.

    The prevalence of patients who receive both a hematopoetic cell(HCT) and solid organ transplantation(SOT) is rising. There have been no large scale studies of HCT…
  • 2016 American Transplant Congress

    HLA Identical or Haploidentical Combined Kidney and Bone Marrow Transplantation for Multiple Myeloma with End-Stage Renal Failure.

    T. Kawai,1 Y.-B. Chen,1 M. Sykes,2 C. Benedict,1 N. Tolkoff-Rubin,1 B. Day,1 S. McAfee,1 K. Ballen, S. David,1 T. Spitzer.1

    1Massachusetts General Hospital, Boston; 2Columbia University, New York.

    Patients with multiple myeloma (MM) who developed end-stage renal disease (ESRD) are generally not eligible for either kidney transplantation or allogeneic stem-cell transplant. We performed…
  • 2015 American Transplant Congress

    Combined Bone Marrow Plus Liver Transplantation in Cynomolgus Monkeys

    J. Weiner, Y. Kato, R. Duran-Struuck, M. Martinez, S. Baker, P. Alonso, J. Zitsman, A. Wu, P. Houck, T. Pinyavat, J. Lefkowitch, S. Chaudhry, T. Kato, M. Sykes, A. Griesemer.

    Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY.

    IntroductionCombined kidney/bone marrow transplantation (CKBMT) induces tolerance in both primates and humans. Since liver is thought to be more tolerogenic than kidney, we hypothesized that…
  • 2015 American Transplant Congress

    Differential Expression and Function of ASC and Nlrp3 Inflammasome Adaptors in Hematopoietic Stem Cells (HSCs)

    A. Scheinok, R. Elahimehr, A. Shigeoka, S. Kasimsetty, D. McKay.

    Medicine, University of California San Diego, San Diego, CA.

    HSCs are activated by pattern recognition receptors (PRRs), which might provide novel targets for improved engraftment. How PRRs affect HSC engraftment after BM transplantation is…
  • 2015 American Transplant Congress

    CD8+TCR– Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem and Progenitor Cells

    Y. Wen,1 Y. Huang,1 T. Miller,1 S. Ildstad.1,2

    1Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; 2Regenerex, LLC, Louisville, KY.

    We recently reported the induction of chimerism and tolerance to renal allografts without GVHD or engraftment syndrome in HLA-mismatched living donor renal transplant recipients through…
  • 2015 American Transplant Congress

    The Role of an Intragraft Vascularized Bone Marrow Niche in Establishing Mixed Chimerism and Allograft Acceptance

    M. Fryer, B. Oh, G. Furtmüller, G. Raimondi, G. Brandacher.

    Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.

    Background: Vascularized composite allotransplantation has emerged as a viable treatment option for patients with devastating tissue loss not amenable to traditional reconstructive techniques. Different from…
  • 2015 American Transplant Congress

    Absence of Nucleotide-Binding Oligomerization Domain-Containing Protein 1 and 2 Modifies Adaptive Immune Responses

    S. Kasimsetty, A. Shigeoka, D. McKay.

    Medicine, UCSD, La Jolla, CA.

    Background:The NOD family of intracellular pattern recognition receptors (PRRs) plays a key role in immune responses to microbial and danger signals. This family of proteins…
  • 2015 American Transplant Congress

    High Incidence of Masked Hypertension in Pediatric Recipients of Stem Cell Transplantation

    A. Melk,1 D. Thurn-Valsassina,1 B. Schmidt,2 R. Beier.3

    1Pediatric Nephrology, Hannover Medical School, Hannover, Germany; 2Nephrology, Hannover Medical School, Hannover, Germany; 3Pediatric Hematology, Hannover Medical School, Hannover, Germany.

    Purpose: Different from recipients of a solid organ transplant, stem cell transplantation (SCT) recipients do not receive long term immunosuppressive treatment that may cause renal…
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