ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Biopsy"

  • 2021 American Transplant Congress

    Baseline Levels of Dd-cf Dna After Pancreas Transplantation: Using Dd-cfdna as an Indicator for Pancreas Rejection and Biopsy Avoidance

    A. Yoo, I. Qian, A. Riedel, C. Cazac, A. Bartosic, J. S. Bromberg, J. Scalea

    Department of Surgery, Division of Transplant, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been previously validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that…
  • 2021 American Transplant Congress

    Impact of Donor Kidney Biopsy on Kidney Yield and Post-Transplant Outcomes

    C. Wang1, J. Wetmore1, A. Wey2, N. Salkowski2, J. Snyder2, A. Israni1

    1Nephrology, Hennepin County Medical Center, Minneapolis, MN, 2Scientific Registry of Transplant Recipients, Minneapolis, MN

    *Purpose: Kidney procurement biopsy findings, such as Glomerulosclerosis (GS) is frequently used to determine kidney quality, but it remains unclear the degree of GS in…
  • 2021 American Transplant Congress

    Evaluation of Serum Klotho Levels at Early Kidney Post-Transplant

    T. Vazquez-Sanchez1, J. Alonso-Titos1, M. Sánchez-Niño2, E. Sola1, M. Leon3, V. Lopez1, P. Ruiz-Esteban1, E. Porrini4, A. Ortiz5, D. Hernández1

    1Nephrology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 2Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Madrid, Spain, 3Pathology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 4Nephrology, Hospital Universitario de Canarias, CIBICAN, Universidadde laLaguna, REDinREN (RD16/0009/0031) Tenerife e Instituto Reina Sofía de Investigación Renal (IRSIN), Malaga, Spain, 5Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Malaga, Spain

    *Purpose: Klotho expression is lowered in patients with chronic kidney disease (CKD). After kidney transplant (KT), serum Klotho levels could be significantly increased compared to…
  • 2021 American Transplant Congress

    Kidney Transplant Biopsy Findings After Covid-19

    E. Daniel1, S. Kudose2, D. J. Cohen1, L. Ratner3, V. D'Agati2, I. Batal2

    1Division of Nephrology, Columbia University Medical Center, NY, NY, 2Department of Pathology, Columbia University Medical Center, NY, NY, 3Department of Surgery, Columbia University Medical Center, NY, NY

    *Purpose: COVID-19 has been reported as a cause of kidney injury and data from published native kidney biopsy results demonstrate a variety of causes. To…
  • 2021 American Transplant Congress

    The Pathology of Heart Allograft Biopsies: Discrepancies in Interpretation Between Conventional Histology and the Molecular Microscope Diagnostic (MMDx®) System

    P. Randhawa1, A. Seitz2, Y. Huang1, B. Feingold2

    1Department of Pathology, Pittsburgh, PA, 2Pediatrics, University of Pittsburgh, Pittsburgh, PA

    *Purpose: There is growing interest in using transcriptomics to complement histologic evaluation of allograft hearts. The present study scrutinizes discrepancies between histologic and MMDx® systems…
  • 2021 American Transplant Congress

    Is Subclinical Allograft Rejection by 2019 Banff Criteria Associated with Worse Kidney Allograft Outcomes? Comparison Between 2007 and 2019 Banff Criteria

    M. T. Victor1, S. Park2, K. Guo1, L. Zhao1, J. Friedewald3

    1Feinberg School of Medicine, Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern Univeristy, Chicago, IL, 3Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: We hypothesize that Subclinical Acute Rejection (SubAR) under the new Banff 2019 criteria will be more strongly associated with a 2-year composite endpoint (2Y-CCE)…
  • 2021 American Transplant Congress

    Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, M. Sugimoto2, O. Konno1, I. Akashi3, M. Okihara1, Y. Kihara1, T. Ueno1

    1Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, 3Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2021 American Transplant Congress

    Covid-19 in a Kidney Transplant Patient Associated with Collapsing Glomerulopathy

    W. Hninn, M. Merzkani, H. Murad, A. Malone, A. Java, G. Rajashekar, R. Delos Santos, T. Alhamad

    Washington University School of Medicine, St. Louis, MO

    *Purpose: Coronavirus- 19 is a novel virus with various clinical presentations ranging from a cold to severe acute respiratory syndrome. However, little is known about…
  • 2021 American Transplant Congress

    Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)

    H. Zhang

    Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…
  • 2021 American Transplant Congress

    Cytomegalovirus Nephritis: Epidemiology and Outcomes of an Uncommon Diagnosis

    K. J. Swanson, A. Djamali, A. Ghaffar, F. Aziz, N. Garg, M. Mohamed, D. A. Mandelbrot, M. Jorgensen, S. Parajuli

    Division of Nephrology, University of Wisconsin-Madison, Madison, WI

    *Purpose: Cytomegalovirus (CMV) nephritis is an uncommon end-organ manifestation of CMV disease. Due to this, associated outcomes have not been completely elucidated.*Methods: This was a…
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