2018 American Transplant Congress
Impact of On-Site Overestimation of Macrosteatosis on Donor Liver Biopsy
Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans.
Introduction: Estimation of hepatic steatosis is an important variable in determining suitability of a donor liver allograft for transplantation. Differentiation between and quantification of macro-…2018 American Transplant Congress
Preoperative Antibiotics Treatment Decreases Endoplasmic Reticulum Stress and Protects Liver Transplant from Ischemia-Reperfusion Injury
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.
Ischemia-reperfusion injury (IRI) represents a major risk factor of graft dysfunction in liver transplantation (LT). We have reported a critical role of endoplasmic reticulum (ER)…2018 American Transplant Congress
Medullary Tissue Sampling in Renal Allograft Biopsy is More Sensitive for Pathologic Diagnosis of PVN
Background Post-transplant polyoma virus nephropathy (PVN) prevalence is 1-10%. Definitive PVN diagnosis requires polyoma virus presence in infected cells, done with immunohistochemical staining for SV40…2018 American Transplant Congress
Real-Time Expert Evaluation of Liver Biopsy for Transplant: The Significance of Smartphone and Microscope Adapter in Telepathology
Introduction: Liver biopsy at the time of procurement plays a crucial role in the acceptance of marginal grafts. Local pathologists and transplant surgery fellows are…2018 American Transplant Congress
Assessing Fibrosis Burden in Renal Allograft with Chronic Damage Using Functional Magnetic Resonance Imaging
Background: Renal allograft fibrosis burden is a strong prognosticator for chronic damage and can only be accurately measured through transplant biopsy at present. We hypothesized…2018 American Transplant Congress
Non-Invasive Proteomics to Detect Biomarkers for Kidney Allograft Dysfunction
Background: Non-invasive biomarkers are needed for monitoring patients to predict early acute rejection (AR). We hypothesized that protein biomarkers released from rejecting allograft tissues can…2018 American Transplant Congress
Reliability of Deceased Donor Procurement Biopsy Images at the Time of Kidney Allocation
Histological findings of procurement deceased-donor kidney biopsies contribute to organ allocation decisions. Representative images of pathology on biopsy slides are often uploaded into United Network…2018 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies as Markers of Post Transplant Focal Segmental Glomerulosclerosis and Proteinuria
Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD.
Background:Angiotensin II type 1 receptor (AT1R) is highly expressed on the endothelial cells and podocytes, which play an essential role in the maintenance of vascular…2018 American Transplant Congress
Complex Combined Thoracic/liver Transplant: A Seven Year Experience
Liver and Pancreas Transplant, UCLA, Los Angeles, CA.
Background: While rare, combined Thoracic/Liver transplants are employed with increasing frequency. Consistent data regarding the technical conduct, patient selection and outcomes in this highly complex…2018 American Transplant Congress
Intragraft MicroRNA Transcriptome of Acute Antibody Mediated Rejection of Human Kidney Allografts
1Weill Cornell Medicine, New York; 2Rockefeller University, New York.
BackgroundMicroRNAs (miRNA) are master regulators of gene expression and are potential therapeutic targets. Intragraft miRNA transcriptome of acute antibody rejection (AMR) of human kidney allograft…
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