2019 American Transplant Congress
HuR Dictates HO-1 Expression, Modulates Inflammation and Influences Recipient Outcomes in Liver Transplant Patients
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver ischemia-reperfusion injury, an innate-immune dominated hepatocellular damage, is a risk factor of early graft dysfunction and rejection in liver transplantation (LT). HuR, an…2019 American Transplant Congress
Kidney Grafts Ultrasound Guided Biopsy Performed By Nephrologist. Regaining Technique And Improving Results
Nephrology, Germans Trias i Pujol Hospital, Badalona, Barcelona, Spain
*Purpose: Stablish the optimal technique and protocol of ultrasound guided renal graft biopsy to be performed by nephrologist compared with previous standard of care, regading…2019 American Transplant Congress
Peritubular Capillary C4d Positivity in Renal Allograft Biopsies: Implications for Allograft Survival
Transplant Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: C4d deposition in the peritubular capillaries (PTCs) is associated with acute antibody mediated rejection (AMR) and reduced renal allograft survival. PTC C4d positivity, however,…2019 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Do Not Portend Future Kidney Function
*Purpose: The predictive ability of implantation biopsies of kidney allografts on either future recipient or living donor kidney function has not been fully elucidated. Herein,…2019 American Transplant Congress
Surveillance Biopsy Utilization Reported Higher In Transplant Centers Performing Over 100 Kidney Transplants Per Year.
*Purpose: To assess the frequency of surveillance biopsies in kidney transplant patients in transplant centers performing greater than 100 transplants per year, and to compare…2019 American Transplant Congress
Absence of Non Alcoholic Fatty Liver Disease in Allografts from Morbidly Obese Donors: A Marker for Success?
Surgery (Division of Surgical Transplantation), UT Southwestern, Dallas, TX
*Purpose: Livers from African-American, morbidly obese donors are less likely to be discarded. We examined the utility of pre-recovery liver biopsy as a predictive biomarker…2019 American Transplant Congress
Borderline Changes in Kidney Allografts Represents a Non-Homogenous Cohort with Different Outcome
*Purpose: Borderline changes (BL) represent a frequent histological finding in kidney allograft with unclear prognosis.*Methods: In this single center, retrospective, observational study, the BL were…2019 American Transplant Congress
Is HLA Donor-Specific Antibody (DSA)-C3d+ Assay a Potential Predictor of Subclinical Antibody Mediated Damage in the Renal Graft?
*Purpose: The Aim of the study was to explore the predictive value of the C3d assay for tissue damage in kidney transplant recipients (KTR) in…2019 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of Kidney Transplant Biopsies
1VCU Medical Center, Richmond, VA, 2Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Circulating donor-derived cell free DNA (cfDNA; Allosure, CareDx, USA), a non-invasive test that could detect rejection in kidney allografts was validated using histologic diagnoses(HDx).…2019 American Transplant Congress
Post-Reperfusion Hepatic Beta-Catenin Activation Regulates Graft Damage, Inflammatory Responses and Transplant Outcomes
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI), an innate-immune driven hepatic inflammation response, represents a major risk factor of early allograft dysfunction (EAD) and rejection in liver…
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