2019 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Do Not Portend Future Kidney Function
*Purpose: The predictive ability of implantation biopsies of kidney allografts on either future recipient or living donor kidney function has not been fully elucidated. Herein,…2019 American Transplant Congress
Rapid Detection of Kidney Transplant Injury by Quantifying Donor-Derived Cell-Free Deoxyribonucleic Acid via Massively Multiplex Polymerase Chain Reaction
1University of California San Francisco, San Francisco, CA, 2Natera Inc., San Carlos, CA
*Purpose: Plasma donor-derived cell-free DNA (dd-cfDNA) is a proven marker for allograft rejection in patients with kidney transplant (KT). Our goal was to assess performance…2019 American Transplant Congress
HuR Dictates HO-1 Expression, Modulates Inflammation and Influences Recipient Outcomes in Liver Transplant Patients
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver ischemia-reperfusion injury, an innate-immune dominated hepatocellular damage, is a risk factor of early graft dysfunction and rejection in liver transplantation (LT). HuR, an…2019 American Transplant Congress
Kidney Grafts Ultrasound Guided Biopsy Performed By Nephrologist. Regaining Technique And Improving Results
Nephrology, Germans Trias i Pujol Hospital, Badalona, Barcelona, Spain
*Purpose: Stablish the optimal technique and protocol of ultrasound guided renal graft biopsy to be performed by nephrologist compared with previous standard of care, regading…2019 American Transplant Congress
Is HLA Donor-Specific Antibody (DSA)-C3d+ Assay a Potential Predictor of Subclinical Antibody Mediated Damage in the Renal Graft?
*Purpose: The Aim of the study was to explore the predictive value of the C3d assay for tissue damage in kidney transplant recipients (KTR) in…2019 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of Kidney Transplant Biopsies
1VCU Medical Center, Richmond, VA, 2Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Circulating donor-derived cell free DNA (cfDNA; Allosure, CareDx, USA), a non-invasive test that could detect rejection in kidney allografts was validated using histologic diagnoses(HDx).…2019 American Transplant Congress
Surveillance Biopsy Utilization Reported Higher In Transplant Centers Performing Over 100 Kidney Transplants Per Year.
*Purpose: To assess the frequency of surveillance biopsies in kidney transplant patients in transplant centers performing greater than 100 transplants per year, and to compare…2019 American Transplant Congress
Absence of Non Alcoholic Fatty Liver Disease in Allografts from Morbidly Obese Donors: A Marker for Success?
Surgery (Division of Surgical Transplantation), UT Southwestern, Dallas, TX
*Purpose: Livers from African-American, morbidly obese donors are less likely to be discarded. We examined the utility of pre-recovery liver biopsy as a predictive biomarker…2019 American Transplant Congress
Borderline Changes in Kidney Allografts Represents a Non-Homogenous Cohort with Different Outcome
*Purpose: Borderline changes (BL) represent a frequent histological finding in kidney allograft with unclear prognosis.*Methods: In this single center, retrospective, observational study, the BL were…2019 American Transplant Congress
High Prevalence of De Novo Donor-Specific Antibodies during Rejection after Liver Transplantation
Liver Transplant Unit, Hospital Clinic Barcelona, Barcelona, Spain
*Purpose: Anti-HLA donor specific antibodies (dnDSA) after liver transplantation (LT) are currently under investigation. Recent studies show an incidence of dnDSA after LT ranging from…
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