2021 American Transplant Congress
Kidney Transplant Biopsy Findings After Covid-19
*Purpose: COVID-19 has been reported as a cause of kidney injury and data from published native kidney biopsy results demonstrate a variety of causes. To…2021 American Transplant Congress
The Pathology of Heart Allograft Biopsies: Discrepancies in Interpretation Between Conventional Histology and the Molecular Microscope Diagnostic (MMDx®) System
1Department of Pathology, Pittsburgh, PA, 2Pediatrics, University of Pittsburgh, Pittsburgh, PA
*Purpose: There is growing interest in using transcriptomics to complement histologic evaluation of allograft hearts. The present study scrutinizes discrepancies between histologic and MMDx® systems…2021 American Transplant Congress
Is Subclinical Allograft Rejection by 2019 Banff Criteria Associated with Worse Kidney Allograft Outcomes? Comparison Between 2007 and 2019 Banff Criteria
*Purpose: We hypothesize that Subclinical Acute Rejection (SubAR) under the new Banff 2019 criteria will be more strongly associated with a 2-year composite endpoint (2Y-CCE)…2021 American Transplant Congress
Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach
*Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…2021 American Transplant Congress
Covid-19 in a Kidney Transplant Patient Associated with Collapsing Glomerulopathy
Washington University School of Medicine, St. Louis, MO
*Purpose: Coronavirus- 19 is a novel virus with various clinical presentations ranging from a cold to severe acute respiratory syndrome. However, little is known about…2021 American Transplant Congress
Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)
Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…2021 American Transplant Congress
Cytomegalovirus Nephritis: Epidemiology and Outcomes of an Uncommon Diagnosis
Division of Nephrology, University of Wisconsin-Madison, Madison, WI
*Purpose: Cytomegalovirus (CMV) nephritis is an uncommon end-organ manifestation of CMV disease. Due to this, associated outcomes have not been completely elucidated.*Methods: This was a…2021 American Transplant Congress
Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections
*Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…2021 American Transplant Congress
Effect of Donor Glomerulosclerosis and Interstitial Fibrosis/Tubular Atrophy (IFTA) on Kidney Graft Survival: A Single Organ Procurement Organization (OPO) Data
1Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 2OneLegacy, Los Angeles, CA
*Purpose: The kidneys of deceased donors are often biopsied to evaluate transplant organ quality. A high percentage of GS is a leading cause of kidney…2021 American Transplant Congress
Beyond Microarrays: Insights from Ncounter Transcript Analysis of Routine Archival Kidney Allograft Biopsies
Massachusetts General Hospital, Boston, MA
*Purpose: Microarray mRNA analysis of renal allograft biopsies has discovered important insights, but has limitations as a practical clinical test. Here we evaluate a new…
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