2019 American Transplant Congress
Balance between Low DNA Concentration and Structural Damage of Extracellular Matrix during Recellularization Procedure as a Key to Successful Recellularization
Foundation of Research and Science Development, Warsaw, Poland
*Purpose: Recellularization is considered to be a potential way to solve the problem of organ shortage for transplantation. One of the conditions for the use…2019 American Transplant Congress
Endothelial Cell Replacement – A Closer Step to Personalized, Tissue-Engineered Transplants
Rabin Medical Center, Petah-Tiqwa, Israel
*Purpose: Whole organ perfusion decellularization has been proposed as a promising method for the generation of non-immunogenic organs from allogeneic or xenogeneic donors. However, the…2019 American Transplant Congress
Ex Vivo Assessment of Marginal Human Kidneys Using Computed Tomography
*Purpose: Thousands of ‘marginal’ organs are discarded each year despite a severe organ shortage. This has motivated development of new technologies, such as ex vivo…2019 American Transplant Congress
MHC Molecule-Ablated Human Endothelial Cells Form Alloimmune-Evasive Microvessels
*Purpose: “Off the shelf” tissue-engineered organs will require use of allogeneic cell sources. Allogeneic human endothelial cells (ECs), necessary for organ perfusion, can initiate graft…2019 American Transplant Congress
Organ Transportation by Drone: Surgeon Perspectives
1University of Maryland, Baltimore, MD, 2Surgery, University of Maryland, Baltimore, MD
*Purpose: We recently reported on the first transport of a human kidney using a drone. Ahead of large scale adoption of such a technology, understanding…2019 American Transplant Congress
Hepatic Stellate Cells and Liver Derived Endothelial Cells Improve Scaffold-Free 3D-Bioprintied Liver Model
*Purpose: Hepatic stellate cells (HSC) comprise about 2-8% of liver cells and are vital to hepatocellular function. Scaffold-free 3D-bioprinting (SF3DBP) allows creation of realistic tissue…2019 American Transplant Congress
Evaluating Liver Regeneration during Normothermic Machine Perfusion in Hepatectomized Rat Liver Model
*Purpose: Realizing the liver’s unique ability to regenerate, this ongoing study examines Normothermic Machine Perfusion (NMP) as a promising platform for evaluating & potentially simulating…2019 American Transplant Congress
Kidney Regeneration with Biomimetic Vascular Scaffolds Based on Vascular Corrosion Casts
*Purpose: We have developed a biomimetic renal vascular scaffold based on a vascular corrosion casting technique. In this study, we evaluated the feasibility of using…2019 American Transplant Congress
Tolerogenic Nanoparticles Targeting the Aryl Hydrocarbon Receptor
*Purpose: The aryl hydrocarbon receptor (AHR) has been shown to have a central role in the ability of dendritic cells (DCs) to direct differentiation of…2019 American Transplant Congress
Preservation of Pancreatic Islets with Stem Cell Derived CD34+ Vascular Endothelial Progenitor Cells
1Surgery, UCSF, San Francisco, CA, 2Diabetes Center, UCSF, San Francisco, CA
*Purpose: Islet transplantation can cure Type 1 diabetes; however, multiple donors are needed due to extensive perioperative loss of islets when removed from their native…
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