2019 American Transplant Congress
Preservation of Pancreatic Islets with Stem Cell Derived CD34+ Vascular Endothelial Progenitor Cells
1Surgery, UCSF, San Francisco, CA, 2Diabetes Center, UCSF, San Francisco, CA
*Purpose: Islet transplantation can cure Type 1 diabetes; however, multiple donors are needed due to extensive perioperative loss of islets when removed from their native…2019 American Transplant Congress
Engineering Regulatory T Cells With TCR-Signaling-Responsive Interleukin 2 Nanoparticles Provides In Situ Suppression Of Alloimmunity
*Purpose: Adoptive cell transfer of regulatory T cells (TReg) has shown great potential in animal models of auto- and alloimmunity. The translation of TReg therapies…2019 American Transplant Congress
Pancreatic Extracellular Matrix Improves Human Islet Culture and Function In Vitro
Virginia Commonwealth University, Richmond, VA
*Purpose: Islet transplantation is a thriving therapy for patients with Chronic Pancreatitis and Type-1 Diabetes. Within the pancreas, the islets are surrounded by Extracellular Matrix…2019 American Transplant Congress
The Efficacy of Spheroidal Hepatocytes for Hepatocyte Transplantation
Department of Gastroenterological Surgery Ⅰ Hokkaido University Graduate School, Sapporo, Japan
*Purpose: Hepatocyte transplantation (HCTx) is expected to expand its application as a next generation therapy alternative to liver transplantation. Following HCTx, the liver function improves…2019 American Transplant Congress
Utilizing Imagestream Technology to Determine Hepatocellular CD38 Localization
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: CD38 is an ecto-enzyme that modulates intracellular calcium levels by producing potent secondary messengers, which utilize the cellular NAD pool and lead to increased…2019 American Transplant Congress
Regeneration of Kidney with a Novel Biomimetic Vascular Scaffold
*Purpose: Appropriate vascularization is one of the most important issues to be addressed in the clinical application of 3D bioengineered organ.*Methods: We have fabricated biomimetic…2019 American Transplant Congress
Modeling Patients as Dynamical Systems: Evaluating the Efficiency of Kidney Transplantation through Multi-Stage Data Envelopment Analysis
*Purpose: The occurrence of kidney graft loss is determined by a large set of variables interacting across the different stages of the transplantation process. This…2019 American Transplant Congress
Towards 3D-Bioprinting of Bionic Pancreas: Effect of Pressure on the Viability of Pancreatic Islets
Foundation for Research and Science Development, Warsaw, Poland
*Purpose: 3D bioprinting is the wave of the future in terms of constructing functional, human organs. 3D bioprinting of a bioactive tissue scaffold and Langerhans…2019 American Transplant Congress
Scaffold-Free 3D-Bioprinting of Human Extrahepatic Bile Duct
*Purpose: Biliary complications are common especially in living and also in deceased donor liver transplantation (LT). Presence of multiple orifices in biliary anastomosis and ischemia,…2019 American Transplant Congress
Balance between Low DNA Concentration and Structural Damage of Extracellular Matrix during Recellularization Procedure as a Key to Successful Recellularization
Foundation of Research and Science Development, Warsaw, Poland
*Purpose: Recellularization is considered to be a potential way to solve the problem of organ shortage for transplantation. One of the conditions for the use…
American Transplant Congress abstracts