ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Bacterial infection"

  • 2020 American Transplant Congress

    High Rate of Positive Cultures from Deceased Donors, A Review of 500 Deceased Donors and More Than 700 Recipients from a Single Center in Saudi Arabia

    R. S. Almaghrabi1, R. Alameer1, O. Zeitoni2, M. Ahmed3, I. Nizami3, J. Alburaiki4, T. Aljurf1, R. Alyamany1, A. Abed2, D. Broering3

    1Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, 2Alfaisal University, Riyadh, Saudi Arabia, 3Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, 4Heart Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: Limited organ supply is one of the major challenges facing organ transplantation. Donor-derived multidrug-resistant (MDR) bacteria have been documented with variable outcomes. In Saudi…
  • 2020 American Transplant Congress

    Lack of Dj-1 Amplifies Sepsis-Associated Acute Kidney Injury and Increases Parenchymal Apoptosis

    J. Leeds1, Y. Scindia2, E. Ghias1, S. Cechova1, V. Loi1, E. Mandziak1, S. Swaminathan1

    1University of Virginia, Charlottesville, VA, 2University of Florida, Gainesville, FL

    *Purpose: Sepsis following kidney transplantation is a frequent complication due to mandatory immunosuppression and increased infection risk. Kidney transplant recipients who develop sepsis show inferior…
  • 2020 American Transplant Congress

    Clinical Features and Outcomes of Post-Transplant Osteomyelitis in Solid Organ Transplant Recipients

    S. Sarwar1, G. Vilchez2, M. M. Azar3, M. Malinis3

    1The Ohio State University Wexner Medical Center, Columbus, OH, 2University of Kentucky College of Medicine, Lexington, KY, 3Yale School of Medicine, New Haven, CT

    *Purpose: As survival time of solid organ transplant recipients (SOTR) increases, comorbidities associated with advancing age such as diabetes mellitus and peripheral arterial disease combined…
  • 2020 American Transplant Congress

    Hyperammonemia Syndrome in a Kidney Transplant Recipient Caused by Quinolone-Resistant Ureaplasma Infection

    A. B. Higgins1, R. Rogers2, A. J. Osband3, R. Gohh4, P. Morrissey3, A. Seo1, B. Chen1, D. Crabb5, S. Leal5, K. Waites5, D. Farmakiotis2, G. J. Nau2

    1Department of Medicine, Alpert Medical School of Brown University, Providence, RI, 2Division of Infectious Diseases, Alpert Medical School of Brown University, Providence, RI, 3Department of Surgery, Alpert Medical School of Brown University, Providence, RI, 4Division of Nephrology, Alpert Medical School of Brown University, Providence, RI, 5Division of Laboratory Medicine, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Urease-producing bacteria release significant amounts of ammonia. Donor-derived Ureaplasma infections in lung transplant recipients have been implicated in the pathogenesis of hyperammonemia syndrome (HS).…
  • 2020 American Transplant Congress

    Antibiotic Pretreatment Alleviates Liver Transplant Damage by Modulating the Composition of Commensal Microbiota

    K. J. Dery, S. Kageyama, H. Hirao, K. Kadono, H. Kojima, R. W. Busuttil, J. W. Kupiec-Weglinski

    Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA

    *Purpose: The human intestinal microbiome contains more than 100 trillion commensal microorganisms, exceeding the number of cells in the human body by 10-fold. Although recent…
  • 2020 American Transplant Congress

    Efficacy and Tolerability of Tedizolid Phosphate in the Treatment of Mycobacterium Abscessus Infection among Pediatric Hematopoietic Stem Cell Transplant Recipients

    Y. Kang, V. M. Aquino, A. Y. Koh, D. Wetzel, P. K. Sue

    Pediatrics, UT Southwestern Medical Center, Dallas, TX

    *Purpose: Mycobacterium abscessus complex infections are associated with high rates of morbidity and mortality in immunocompromised hosts. Treatment can be challenging due to broad spectrum…
  • 2020 American Transplant Congress

    Risk Factors for Bacterial or Candidal Donor-Derived Infections among Solid Organ Transplant Recipients

    J. A. Anesi1, E. Lautenbach1, J. H. Han2, D. H. Lee3, H. Clauss4, R. Hasz5, E. Molnar4, D. Alimenti1, A. R. Motzer4, S. West5, W. B. Bilker1, P. Tolomeo1, E. A. Blumberg1, T. Prevention Epicenters Program6

    1University of Pennsylvania, Philadelphia, PA, 2GlaxoSmithKline, Rockville, MD, 3Drexel University, Philadelphia, PA, 4Temple University, Philadelphia, PA, 5Gift of Life Donor Program, Philadelphia, PA, 6Centers for Disease Control and Prevention, Atlanta, GA

    *Purpose: Donor-derived infections (DDIs) among solid organ transplant recipients (SOTR) are often associated with significant morbidity and mortality, although the predisposing factors for DDIs remain…
  • 2020 American Transplant Congress

    Treatment of Hepatic Encephalopathy in Cirrhotic Patients: Does Rifaximin Prevent Clostridioides Difficile Infection? A Retrospective Analysis

    J. D. Goldman, V. Aleksenko, J. L. Davila, N. A. Muhktar, K. Kowdley

    Swedish Medical Center, Seattle, WA

    *Purpose: Clostridioides difficile infection (CDI) is a major cause of morbidity and mortality and new prevention strategies in high-risk patients are needed. Rifaximin has been…
  • 2020 American Transplant Congress

    Use of 16S Sequencing to Reveal Potential Respiratory Pathogens in Lung Transplant Recipients

    C. Eskind1, M. Shilts1, H. Boone1, J. Schmitz2, C. Shaver3, S. Das1, G. Satyanarayana1

    1Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, 2Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 3Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Respiratory infections are common after lung transplant and contribute to mortality and allograft failure. 16S ribosomal RNA (rRNA) gene sequencing could facilitate diagnosis of…
  • 2019 American Transplant Congress

    Clostridium difficile Infection Mimics Intestinal Acute Cellular Rejection in Pediatric Multivisceral Transplant – A Case Series

    D. A. Cheung1, T. Beduschi2, A. Tekin2, G. Selvaggi2, R. M. Vianna2, J. Garcia1

    1Pediatric Gastroenterology, University of Miami, Miami, FL, 2Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL

    *Purpose: Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. One out of 8 recipients who undergo transplantation with more…
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