2019 American Transplant Congress
Blockade of IL-1β and TNF-α Does Not Significantly Pose Risk or Affect Outcomes in Patients Infused with Microbial-Positive Autologous Islet Preparations
*Purpose: We recently demonstrated that the combined use of anakinra (IL-1β blocker) and etanercept (TNF-α blocker) improved outcomes of islet autotransplantation after total pancreatectomy (TPIAT).…2019 American Transplant Congress
Clostridium difficile Infection Mimics Intestinal Acute Cellular Rejection in Pediatric Multivisceral Transplant – A Case Series
*Purpose: Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. One out of 8 recipients who undergo transplantation with more…2019 American Transplant Congress
Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients at an Academic Medical Center
Center for Transplantation, University of California, San Diego Health System, La Jolla, CA
*Purpose: In the United States, the incidence of Clostridium difficile infection (CDI) has increased remarkably and remains a significant burden in the solid organ transplant…2019 American Transplant Congress
Predictors of Multidrug-Resistant Organisms among Solid Organ Transplant Donors
*Purpose: Transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs). Approaches to identifying such potentially…2019 American Transplant Congress
Donor Derived Tuberculosis in Solid Organ Transplantation in the United States: 10 Years of UNOS Ad Hoc Disease Transmission Advisory Committee Experience
1DTAC, Richmond, VA, 2UNOS, Richmond, VA
*Purpose: Mycobacterium tuberculosis can be transmitted via organ donation. Failure to recognize tuberculosis (TB) may result in significant morbidity and mortality. Currently, donor screening for…2019 American Transplant Congress
Impact of Multidrug-Resistant Organisms among Donors on Organ Utilization
*Purpose: Though transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs), the true impact of…2019 American Transplant Congress
Impact of Multidrug-Resistant Microbes of Donor Lower Respiratory Tract on Early Posttransplant Pneumonia in Bilateral Lung Transplant Recipients without Pretransplant Infection
*Purpose: Colonized microbes in lower respiratory tract (LRT) of deceased donor allograft can potentially cause early posttransplant pneumonia (EPTP) that leads to detrimental outcome in…2019 American Transplant Congress
Transmission of Infections from Organ Donor to Recipient – German Data
German Foundation for Organtransplantation (DSO), Frankfurt, Germany
*Purpose: In Europe, vigilance monitoring after organ transplant includes Serious Adverse Events (SAE) as well as Serious Adverse Reactions (SAR). All SAE and SAR related…2019 American Transplant Congress
Treatment of Pseudomonas Infection with Beta-Lactams Including Ceftolozane-Tazobactam in Solid Organ Transplant Recipients
*Purpose: Ceftolozane/Tazobactam (CT) is a potent anti-pseudomonal agent with broad gram-negative activity. Our academic medical center recommends the use of CT for patients with a…2019 American Transplant Congress
Daptomycin Perioperative Prophylaxis for Prevention of Vancomycin-Resistant Enterococcus Infection in VRE-Colonized Liver Transplant Recipients during the Early Post-Transplant Period
Section of Infectious Diseases, Department of Medicine, Yale School of Medicine, New Haven, CT
*Purpose: Antibiotic prophylaxis for enteric pathogens is recommended before liver transplantation (LT). Perioperative screening protocols and antimicrobials vary between institutions. Some institutions that do not…
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