2018 American Transplant Congress
Pharmacokinetics of Mycophenolic Acid Following Enteric-Coated Mycophenolate Sodium Administration in Chinese Renal Transplant Recipients
MyERA Study Group, Hangzhou, China.
Background: Mycophenolic acid (MPA), active component of mycophenolate mofetil (MMF) or enteric-coated mycophenolate sodium (EC-MPS), is the most commonly used immunosuppressant in renal transplant recipients…2018 American Transplant Congress
The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants
Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…2018 American Transplant Congress
Improving Prediction of Post-Transplant Death and Graft Loss with Expanded Clinical Data Collection
US transplant centers are graded for patient and graft survival of their recipients based on comparison to risk-adjusted expectations using elements captured in the national…2018 American Transplant Congress
Identification of Noninvasive and Mechanistically-Informative Biomarkers Predictive of Reversal of Acute Cellular Rejection (ACR) in Kidney Allografts
1University of Michigan, Ann Arbor, MI; 2Weill Cornell Medical College, New York City, NY.
Objective: We determined whether urinary cell mRNAs predict response to anti-rejection therapy in kidney allograft recipients with Banff grade IA or higher ACR biopsies.Methods: We…2018 American Transplant Congress
Absolute Quantification of Plasma Graft-Derived Cell-Free DNA for Diagnosis of Kidney Transplant Rejection
Aim: To study the performance of droplet digital PCR absolute measurement of graft-derived cell-free DNA (gdcfDNA) for the diagnosis of kidney allograft rejection.Methods: Homozygous deletion…2018 American Transplant Congress
Outcomes from Brain Death Donors with Cardiac Arrest Accepted for Pancreas Transplantation
Donor selection has a major impact on pancreas transplantation. Cardiac arrest and hypoxemia produce an insult to endothelial cell and may increase the risk of…2018 American Transplant Congress
Evaluating PROMIS-57 Domains to Screen for Anxiety and Depression Using Legacy Instruments among Kidney Transplant Recipients
BACKGROUNDDepression and anxiety are frequent among kidney transplant recipients (KTRs). We evaluate the accuracy of the Patient Reported Outcomes Measurement System (PROMIS 57 item) depression…2017 American Transplant Congress
Model to Predict Prolonged Delayed Graft Function (DGF) Following Kidney Transplantation from Deceased Donor with Acute Kidney Injury (AKI Tx).
1Mayo Clinic, Phoenix, AZ; 2Mayo Clinic, Rochester, MN
Background Our aim is to develop a model to predict prolonged DGF following AKI Tx.Methods AKI Tx (donor terminal Cr>/=2) from 2003 to 2016 were…2017 American Transplant Congress
An Analysis of Tacrolimus XL Dosing in Obese Kidney Transplant Recipients.
Background:Tacrolimus extended-release (XL) is utilized in many immunosuppressive regimens post-kidney transplantation. Current dosing recommendation for the XL formulation in renal transplant (txp) is 0.15 mg/kg/day…2017 American Transplant Congress
Once-Daily versus Twice-Daily Tacrolimus in Living Kidney Transplantation: A Multicenter, Parallel Group, Open-Label, 5-Year, Randomized Non-Inferiority Trial.
Background:Tacrolimus (TAC)-based induction therapy appears to be the standard immunosuppressive regimen for most kidney transplantation recipients (KTRs). TAC is available as a twice-daily (TAC-BID) and…
American Transplant Congress abstracts