2022 American Transplant Congress
Development of a Radiomics-Based Model to Predict Graft Fibrosis in Liver Transplant Recipients: A Pilot Study
*Purpose: Recurrent fibrosis complicates 40% of Liver transplants (LT), compromising long-term survival. We evaluated the ability of a model combining radiomic features on CT scans…2022 American Transplant Congress
Meld Score <31 Predicts Spontaneous Recovery in Patients Listed for Liver Transplantation for Alcohol-Associated Hepatitis: A UNOS Database Study
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: Alcohol-associated hepatitis (AH) is the fastest growing indication for liver transplantation (LT) in the U.S. While spontaneous recovery (SR) can occur in patients with…2022 American Transplant Congress
Tacrolimus and Mycophenolic Acid Therapeutic Exposure Targets in Black and White Kidney Transplant Recipients
1Univeristy at Buffalo/SUNY, Buffalo, NY, 2Ohio State Medical Center, Columbus, OH
*Purpose: Tacrolimus and Mycophenolic Acid(MPA), the preferred immunosuppressive regimen for kidney transplant recipients(KTR), exhibit interpatient pharmacokinetic variability which may impact allograft survival in Black and…2022 American Transplant Congress
Galectin-3 Discriminates Patients with Advanced Cirrhosis and Predicts Post-Liver Transplant Infectious Complications
*Purpose: An increased demand for liver transplantation (LT) prevails. Galectin-3 is a lectin implicated in inflammation, immunoregulation, and liver fibrosis. In this study we assessed…2022 American Transplant Congress
Utility of Four-Point Mycophenolate Mofetil Testing in a Pediatric Kidney Transplant Population
Pediatric Nephrology, UCSF, San Francisco, CA
*Purpose: While there is randomized, multicenter data in adults that area under the time concentration curve (AUC) measurements for Mycophenolate Mofetil (MMF) can direct dosing…2022 American Transplant Congress
Post-Kidney Transplant Valacyclovir or Valganciclovir for EBV Prophylaxis: A Randomized Controlled Trial
*Purpose: EBV viremia post-kidney transplant (KTx) has no proven prophylaxis.*Methods: In this randomized, open-label trial [NCT01329185], adult and pediatric recipients were randomly assigned (1:1) to…2022 American Transplant Congress
Dynamic Risk Prediction of Kidney Graft Failure After Deceased Donor Transplant
*Purpose: Identifying kidney transplant recipients at risk of graft failure allows for early intervention in clinical care. We developed a dynamic risk prediction model based…2021 American Transplant Congress
Tacrolimus Therapeutic Exposure is Not Consistently Predicted by Target Troughs or CYP3A5 Variants in Stable Renal Transplant Recipients
*Purpose: Tacrolimus (TAC) immunosuppression requires therapeutic trough monitoring post-transplant due to notable interpatient pharmacokinetic(PK) variability which may be attributed to CYP3A5 polymorphisms. We investigated the…2021 American Transplant Congress
Exploring the Correlation with Donor Hepatitis C Viral Load and Viral Kinetics in Naïve Kidney Transplantation Recipients
*Purpose: The transplantation of Hepatitis C viremic (HCV) kidneys into uninfected recipients was made possible by effective direct acting anti-viral (DAA) therapy. This study aims…2021 American Transplant Congress
Offer Acceptance Models for Various Endpoints: Initial Response, Final Response, and Conversion from Provisional Yes to Yes
United Network for Organ Sharing, Richmond, VA
*Purpose: Offer acceptance models are routinely used for program evaluation and academic research, but the focus tends to be on modelling the final offer response.…
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