ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Antilymphocyte antibodies"

  • 2019 American Transplant Congress

    To Each Their Own: Center-Level Variation in Tailoring Induction Immunosuppression to Kidney Transplant Recipients

    S. Bae, A. Massie, J. Garonzik Wang, M. McAdams DeMarco, J. Coresh, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Ideally, induction immunosuppression should be selected in a personalized manner. However, there is little knowledge of what clinical factors are considered in this process…
  • 2019 American Transplant Congress

    Low Dose Anti-Thymocyte Globulin is Enough to Prevent Acute Cellular Rejection in Kidney Transplant

    P. W. Baron1, J. Weissman2, F. Fazeli3, C. Zuppan4, R. Villicana3, P. Wai1, L. Beeson5, M. De Vera1

    1Surgery/Transplantation Institute, Loma Linda University Health, Loma Linda, CA, 2Pharmacy, Loma Linda University Health, Loma Linda, CA, 3Transplantation Institute, Loma Linda University Health, Loma Linda, CA, 4Pathology, Loma Linda University Health, Loma Linda, CA, 5Center for Nutrition, Healthy Lifestyle and Disease Prevention/School of Public Health, Loma Linda University Health, Loma Linda, CA

    *Purpose: Rabbit anti-thymocyte globulin (rATG) cumulative dose needed to effectively and safely prevent acute cellular rejection is unknown. This study compares the efficacy of total…
  • 2019 American Transplant Congress

    Alemtuzumab versus Antithymocyte Globulin Induction Immunosuppression in Highly Sensitized Kidney Transplant Recipients

    A. Brueckner1, E. Yanqui1, C. Truong1, R. Baliga2, L. Bowman1

    1Tampa General Hospital, Tampa, FL, 2Florida Kidney Physicians, Tampa, FL

    *Purpose: Lymphocyte depleting agents such as rabbit anti-thymocyte globulin (rATG) and alemtuzumab are used for induction in highly sensitized (PRA ≥30%) kidney transplant recipients (KTRs).…
  • 2019 American Transplant Congress

    No Indication of Increased CMV Infection in Kidney Transplant Recipients without Pharmacological Prophylaxis Receiving a Single 3mg/kg Dose of Rabbit Anti-Thymocyte Globulin (ATG) Instead of No-Induction

    M. Ivani de Paula, M. Grace Bowring, A. A. Shaffer, J. Garonzik-Wang, A. Barros Bessa, C. Rosso Felipe, M. Pontello Cristelli, A. B. Massie, J. Medina Pestana, H. Silva Junior, D. L. Segev

    Hospital do Rim, Nephrology Division, EPM - UNIFESP, São Paulo, Brazil

    *Purpose: Induction therapy with rabbit anti-thymocyte globulin (ATG) in patients at low immunological risk remains controversial, given increased risk of cytomegalovirus (CMV) infection*Methods: To investigate…
  • 2019 American Transplant Congress

    Comparison of Long-Term Outcomes between Alemtuzumab and Rabbit Anti-Thymocyte Globulin for Acute Kidney Allograft Rejection

    M. van der Zwan, M. C. Clahsen-van Groningen, D. L. Roelen, M. W. van den Hoogen, M. Van Agteren, J. I. Roodnat, C. C. Baan, D. A. Hesselink

    Erasmus MC, Rotterdam, Netherlands

    *Purpose: T cell-depleting antibody therapy with rabbit anti-thymocyte globulin (rATG) is the treatment of choice for glucocorticoid-resistant, recurrent and/or severe acute kidney allograft rejection (AR).…
  • 2019 American Transplant Congress

    Case Series: Anti-Thymocyte Globulin as a Treatment for Steroid-Refractory Severe Acute Hepatitis in Children

    A. L. Peters, A. Miethke, K. Campbell

    Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: Pediatric severe acute hepatitis (SAH), when not attributed to acetaminophen toxicity, is commonly hypothesized to be caused by a non-typeable viral infection and/or immune…
  • 2019 American Transplant Congress

    ABMR In Low-single Dose Thymoglobulin Induction Protocol In Renal Transplant Recepients From A Tertiary Care Centre In A Developing Country

    R. Parthasarathy1, M. Mohammed1, P. Koshy2, I. Pradeep2, M. Mathew1, G. Abraham1

    1Nephrology, Madras Medical Mission, Chennai, India, 2Pathology, Madras Medical Mission, Chennai, India

    *Purpose: Fool proof induction therapy in low sensitized patients is still elusive. There is a thin line between over immunosuppression and infection . Conventional rabbit…
  • 2019 American Transplant Congress

    Retrospective Nested Case Control Study of the Impact of Immunosuppression on Post Transplant Malignancy among Adult Heart Transplant Patients

    S. Crow, R. J. Bubik, S. S. Kushwaha, K. C. Mara, R. A. Dierkhising, N. L. Pereira

    Mayo Clinic, Rochester, MN

    *Purpose: Post-transplant malignancy is diagnosed in approximately 18% of heart transplant (HTx) recipients and is a leading long-term cause of death among these patients. The…
  • 2018 American Transplant Congress

    Comparison of Induction and Maintenance Immunosuppression Regimens in Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Registry

    S. Nagai,1 M. Rizzari,1 Y. Muszkat,2 K. Collins,1 A. Yoshida,1 S-.M. Jafri,2 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI.

    Aim: Induction and maintenance immunosuppression regimens in intestinal transplant widely vary among centers. The aim of this study was to investigate an association between immunosuppression…
  • 2018 American Transplant Congress

    Thymoglobulin Induction Decreases Risk of Death in HLA-Sensitized Kidney Recipients

    C. Loheac, O. Aubert, M. Assayag, D. Viglietti, C. Lefaucheur, A. Loupy.

    Paris Translational Research Center for Organ Transplantation, Paris, France.

    Anti-thymocyte globulin (ATG) is currently the preferential induction treatment in kidney recipients at high risk for allograft rejection. However, no study has evaluated the benefits…
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