ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Antilymphocyte antibodies"

  • 2022 American Transplant Congress

    Steroid-Free Living Donor Liver Transplantation Using Rabbit Antithymocyte Globulin Induction Reduces Incidence of Acute Cellular Rejection

    C. Eymard1, S. Naik1, J. Eason2

    1James D Eason Transplant Institute, Memphis, TN, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: The efficacy of steroid-free immunosuppression protocols using rabbit antithymocyte globulin (RATG) induction with tacrolimus minimization has previously been described in deceased donor liver transplantation.…
  • 2021 American Transplant Congress

    Dosing Weight of Rabbit Antithymocyte Globulin and Outcomes Among Kidney Transplant Patients Treated for Rejection

    C. Patton, K. Cunningham, C. D'Agostino, A. Novak, M. Kapugi, K. Lang, C. Kane

    Pharmacy, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Rabbit antithymocyte globulin (rATG) is FDA approved for kidney transplant induction therapy and treatment of T-cell mediated rejection (TCMR). While prior studies comparing dosing…
  • 2021 American Transplant Congress

    Continuous 24-Hour Antithymocyte Globulin (ATG) for Renal Allograft Rejection: Results of a Randomized Controlled Trial

    S. J. Patel, A. Rogers, S. Kuten, R. Knight, E. Graviss, D. Nguyen, T. Ellimuttil, I. Agboli, L. Gaber, A. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: For acute renal allograft rejection (AR), ATG is generally administered in the inpatient setting because of the need for intravenous access, patient monitoring, and…
  • 2021 American Transplant Congress

    Association Between Cumulative Antithymocyte Globulin Dosing and Adverse Outcomes in Pediatric Heart Transplant Recipients

    J. Chen1, D. Salerno1, H. Corbo1, S. Shah2, A. Rothkopf3, I. D. Lytrivi3

    1Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 2College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 3Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY

    *Purpose: Lymphocyte depletion via rabbit antithymocyte globulin (rATG) is the most frequently used induction immunosuppressive in pediatric orthotopic heart transplant (OHT). Although outcomes are often…
  • 2021 American Transplant Congress

    No Benefit of Antithymocyte Globulin in Living Donor Liver Transplant Recipients

    N. Wilson, P. Nguyen, G. Saracino, R. Patel, G. Testa, T. Sam

    Baylor University Medical Center, Dallas, TX

    *Purpose: Acute rejection after liver transplant is associated with increased risk of graft failure and mortality. Reports on rejection rates in living donor liver transplants…
  • 2021 American Transplant Congress

    Outcomes in Standard vs. Extended Use of Thymoglobulin as Induction Therapy in Kidney Transplant Recipients

    N. M. Sifontis1, A. Coleman1, D. Tang1, K. Lau2, S. Karhadkar2, A. DiCarlo2, A. Diamond2

    1Temple University School of Pharmacy, Philadelphia, PA, 2Temple University Health System, Philadelphia, PA

    *Purpose: Thymoglobulin induction along with modern maintenance immunosuppression has been found to have a significant reduction in acute rejection in kidney transplantation. The recommended duration…
  • 2021 American Transplant Congress

    A Question with Multiple Answers: Do Renal Transplant Recipients Require Steroid Maintenance Following Thymoglobulin Induction?

    A. Aala, H. Patel, F. Cardarelli

    Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: Anti-thymocyte globulin (ATG) has been used with good results in renal transplantation as induction therapy, followed by triple immunosuppression with calcineurin inhibitors, antimetabolites, and…
  • 2020 American Transplant Congress

    Carfilzomib-Based Desensitization: Effects on HLA, Non-HLA, Auto, and Antiviral Antibodies

    S. Tremblay1, E. Portwood1, A. R. Shields2, R. R. Alloway1, P. A. Brailey1, E. Woodle1

    1U Cincinnati, Cincinnati, OH, 2U Cincinnati, Christ Hospital, Cincinnati, OH

    *Purpose: An important question in plasma cell (PC) therapies is the specificity of therapy for PC populations. It is known that plasmablast populations are exquisitely…
  • 2020 American Transplant Congress

    Thymoglobulin Dose and Incidence of Biopsy Proven Acute Rejections in the Early Post Transplant Period

    K. Shimko, K. Schonder, D. Jorgensen, K. Kalra, A. Cherukuri, R. Mehta, I. Melgarejo, P. Sood, S. Hariharan, R. Mehta

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Optimal dosing of thymoglobulin (ATG) for induction has not been well defined. Our protocol aims for 5-6mg/kg cumulative dose divided over 4 doses. However,…
  • 2020 American Transplant Congress

    Short Term Outcomes in Kidney Transplant Patients Receiving De Novo Belatacept with Anti-Thymocyte Globulin Induction

    B. Carlson, P. Cabrera, T. Harrison, K. Tejani, A. Centeno

    Pharmacy, Jackson Memorial Hospital, Miami, FL

    *Purpose: Mainstay immunosuppressive therapy after kidney transplant is a calcineurin inhibitor (CNI) based regimen. Nephrotoxicity is a common adverse effect of CNIs which can lead…
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