2022 American Transplant Congress
Kidney Transplantation Utilizing SARS-CoV-2 Rt-PCR Positive Donor Kidneys with Immediate Post Exposure Casirivimab /Imdevimab Followed by Thymoglobulin Induction
*Purpose: At the beginning of the pandemic, kidneys from SARS-CoV-2 (COVID) RT-PCR positive donors were not utilized for transplantation, due to the risk of viral…2021 American Transplant Congress
Association Between Cumulative Antithymocyte Globulin Dosing and Adverse Outcomes in Pediatric Heart Transplant Recipients
*Purpose: Lymphocyte depletion via rabbit antithymocyte globulin (rATG) is the most frequently used induction immunosuppressive in pediatric orthotopic heart transplant (OHT). Although outcomes are often…2021 American Transplant Congress
Continuous 24-Hour Antithymocyte Globulin (ATG) for Renal Allograft Rejection: Results of a Randomized Controlled Trial
Houston Methodist Hospital, Houston, TX
*Purpose: For acute renal allograft rejection (AR), ATG is generally administered in the inpatient setting because of the need for intravenous access, patient monitoring, and…2021 American Transplant Congress
Dosing Weight of Rabbit Antithymocyte Globulin and Outcomes Among Kidney Transplant Patients Treated for Rejection
Pharmacy, Northwestern Memorial Hospital, Chicago, IL
*Purpose: Rabbit antithymocyte globulin (rATG) is FDA approved for kidney transplant induction therapy and treatment of T-cell mediated rejection (TCMR). While prior studies comparing dosing…2021 American Transplant Congress
A Question with Multiple Answers: Do Renal Transplant Recipients Require Steroid Maintenance Following Thymoglobulin Induction?
Beth Israel Deaconess Medical Center, Boston, MA
*Purpose: Anti-thymocyte globulin (ATG) has been used with good results in renal transplantation as induction therapy, followed by triple immunosuppression with calcineurin inhibitors, antimetabolites, and…2021 American Transplant Congress
Outcomes in Standard vs. Extended Use of Thymoglobulin as Induction Therapy in Kidney Transplant Recipients
*Purpose: Thymoglobulin induction along with modern maintenance immunosuppression has been found to have a significant reduction in acute rejection in kidney transplantation. The recommended duration…2021 American Transplant Congress
No Benefit of Antithymocyte Globulin in Living Donor Liver Transplant Recipients
Baylor University Medical Center, Dallas, TX
*Purpose: Acute rejection after liver transplant is associated with increased risk of graft failure and mortality. Reports on rejection rates in living donor liver transplants…2020 American Transplant Congress
Anti-Thymocyte Globulins Induced Immunomodulatory Effect and Increased Regulatory T Cell in a In Vitro Model of Allogeneic Cell Coculture
*Purpose: Two types of Anti-Thymocyte Globulins (ATG) are commonly used in renal transplantation (Thymoglobuline and Grafalon) and induce severe, dose-dependent and sometimes persistent CD4+ T…2020 American Transplant Congress
Carfilzomib-Based Desensitization: Effects on HLA, Non-HLA, Auto, and Antiviral Antibodies
1U Cincinnati, Cincinnati, OH, 2U Cincinnati, Christ Hospital, Cincinnati, OH
*Purpose: An important question in plasma cell (PC) therapies is the specificity of therapy for PC populations. It is known that plasmablast populations are exquisitely…2020 American Transplant Congress
Thymoglobulin Dose and Incidence of Biopsy Proven Acute Rejections in the Early Post Transplant Period
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Optimal dosing of thymoglobulin (ATG) for induction has not been well defined. Our protocol aims for 5-6mg/kg cumulative dose divided over 4 doses. However,…
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