ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Antilymphocyte antibodies"

  • 2022 American Transplant Congress

    Thymoglobulin Induction Protocol: Quality Improvement Project via Clinical Audit

    S. Mouawad1, J. Dann1, A. Kumar2, S. Rao3

    1University of Virginia Health System, Charlottesville, VA, 2Nephrology, University of Virginia, Charlottesville, VA, 3University of Virginia, Charlottesville, VA

    *Purpose: The aim of our study was to analyze the adequacy of the thymoglobulin (rATG) induction protocol for the expanding and higher complexity kidney transplant…
  • 2021 American Transplant Congress

    Association Between Cumulative Antithymocyte Globulin Dosing and Adverse Outcomes in Pediatric Heart Transplant Recipients

    J. Chen1, D. Salerno1, H. Corbo1, S. Shah2, A. Rothkopf3, I. D. Lytrivi3

    1Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 2College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 3Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY

    *Purpose: Lymphocyte depletion via rabbit antithymocyte globulin (rATG) is the most frequently used induction immunosuppressive in pediatric orthotopic heart transplant (OHT). Although outcomes are often…
  • 2021 American Transplant Congress

    Continuous 24-Hour Antithymocyte Globulin (ATG) for Renal Allograft Rejection: Results of a Randomized Controlled Trial

    S. J. Patel, A. Rogers, S. Kuten, R. Knight, E. Graviss, D. Nguyen, T. Ellimuttil, I. Agboli, L. Gaber, A. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: For acute renal allograft rejection (AR), ATG is generally administered in the inpatient setting because of the need for intravenous access, patient monitoring, and…
  • 2021 American Transplant Congress

    Dosing Weight of Rabbit Antithymocyte Globulin and Outcomes Among Kidney Transplant Patients Treated for Rejection

    C. Patton, K. Cunningham, C. D'Agostino, A. Novak, M. Kapugi, K. Lang, C. Kane

    Pharmacy, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Rabbit antithymocyte globulin (rATG) is FDA approved for kidney transplant induction therapy and treatment of T-cell mediated rejection (TCMR). While prior studies comparing dosing…
  • 2021 American Transplant Congress

    A Question with Multiple Answers: Do Renal Transplant Recipients Require Steroid Maintenance Following Thymoglobulin Induction?

    A. Aala, H. Patel, F. Cardarelli

    Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: Anti-thymocyte globulin (ATG) has been used with good results in renal transplantation as induction therapy, followed by triple immunosuppression with calcineurin inhibitors, antimetabolites, and…
  • 2021 American Transplant Congress

    Outcomes in Standard vs. Extended Use of Thymoglobulin as Induction Therapy in Kidney Transplant Recipients

    N. M. Sifontis1, A. Coleman1, D. Tang1, K. Lau2, S. Karhadkar2, A. DiCarlo2, A. Diamond2

    1Temple University School of Pharmacy, Philadelphia, PA, 2Temple University Health System, Philadelphia, PA

    *Purpose: Thymoglobulin induction along with modern maintenance immunosuppression has been found to have a significant reduction in acute rejection in kidney transplantation. The recommended duration…
  • 2021 American Transplant Congress

    No Benefit of Antithymocyte Globulin in Living Donor Liver Transplant Recipients

    N. Wilson, P. Nguyen, G. Saracino, R. Patel, G. Testa, T. Sam

    Baylor University Medical Center, Dallas, TX

    *Purpose: Acute rejection after liver transplant is associated with increased risk of graft failure and mortality. Reports on rejection rates in living donor liver transplants…
  • 2020 American Transplant Congress

    Outcomes of Induction with T Lymphocyte-Depleting and IL-2 Receptor Blocking (IL-2RB) Antibodies in the Non-Broadly Sensitized Adult Deceased-Donor Kidney Transplant Recipients: Analysis in the Context of the CPRA Allocation System

    A. H. Santos Jr1, Y. Li2, K. Alquadan1, M. Leghrouz1, X. Wen3

    1Div. of Nephrology, Univ. of Florida, Gainesville, FL, 2Univ. of Florida, Gainesville, FL, 3Univ. of Rhode Island, Kingston, RI

    *Purpose: We studied outcomes of induction in non-broadly-sensitized adult deceased-donor kidney transplant recipients(DD-KTRs) in the context of the calculated panel reactive antibody (CPRA) allocation system.*Methods:…
  • 2020 American Transplant Congress

    Induction Therapy with Basiliximab versus Thymoglobulin in African-American Kidney Transplant Recipients in the Current Era of Immunosuppression

    M. Zachariah1, I. Mallawaarachchi2, N. Meeks3, D. Wright1, R. Minawala1, V. Liu1, J. Rolls4, S. Hussein4, C. Jarrin5

    1Wayne State University, Detroit, MI, 2Division of Biostatistics, University of Virginia, Charlottsville, VA, 3Wayne State University School of Medicine, Detroit, MI, 4Surgery, Detroit Medical Center, Detroit, MI, 5Infectious Disease, Wayne State University, Detroit, MI

    *Purpose: It is now common practice in the transplant community to select induction therapy on the basis of perceived immunological risk for acute rejection which…
  • 2020 American Transplant Congress

    Renal Transplant Induction Therapy Safety Outcomes Comparison

    R. M. Hofmann1, J. Combs2, K. J. Schmidt3, T. Dyckman4

    1Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, 2Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, 3Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, 4Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI

    *Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
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