2016 American Transplant Congress
The Impact of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx) Is Independent of Time Post-Transplant.
Detection of MVI in a KTxBx, often associated with antibody mediated rejection, is associated with a poor prognosis for kidney graft survival. However most information…2016 American Transplant Congress
Pregnancy Excludes Women from Successful Living Donor Transplantation.
INTRODUCTION Pregnancy-induced sensitization (PIS) is a barrier to the transplantation of women and contributes significantly to gender disparity in transplantation. We hypothesized that this barrier…2016 American Transplant Congress
Post-Transplant T-Cell Alloreactive Perturbation Precedes the Advent of Humoral Immunity in Kidney Transplant Patients.
Subclinical inflammation in kidney allografts is associated with worse outcome and the activation of humoral alloimmunity. Surveillance allograft biopsies are an accurate tool to diagnose…2016 American Transplant Congress
MHC/HLA-Specific IgE in Allotransplantation.
Background: Donor-specific antibodies (DSA) are recognized as important factors in determining outcome in renal transplantation.Typically DSAs of the IgG isotype are measured, but little is…2016 American Transplant Congress
Thrombalexin: Detection & Efficacy of a Membrane-Bound Anti-Thrombin Agent.
1Surgery, Duke University, Durham; 2King's College, London, United Kingdom.
Introduction: Early activation of coagulation may be an important factor in the initiation of innate immunity. Anti-coagulation in the transplant setting is difficult due to…2016 American Transplant Congress
African-American Primary Renal Transplant Recipients Are at a Significantly Higher Risk to Develop De Novo DSA.
Recent studies have shown multiple risk factors for de novo DSA (dnDSA) development. One controversial risk factor is race. Studying a primarily African-American (AA) transplant…2016 American Transplant Congress
Limited Efficacy of Bortezomib on Desensitization via Rapid Humoral Compensation in a Sensitized Rhesus Model.
1Surgery, Duke University, Durham; 2Surgery, Emory University, Atlanta.
Sensitized patients comprise a significant proportion (30%) of candidates on the waiting list for transplantation. With recent evidence that the presence of donor-specific antibodies (DSA)…2016 American Transplant Congress
Impact of Donor Specific Antibodies on Cardiac Allograft Vasculopathy.
Purpose: Cardiac allograft vasculopathy (CAV) is a significant complication after cardiac transplantation (CTX). The presence of donor specific antibodies (DSA) has been associated with an…2016 American Transplant Congress
Factors Predicting Risk for Antibody-Mediated Rejection in Highly Sensitized Pediatric Renal Transplants.
Introduction: Antibody-mediated rejection (ABMR) is a concern in highly sensitized (HS) patients (pts) receiving renal transplant (tx). We have previously published that a donor specific…2016 American Transplant Congress
Ischemia Reperfusion Induced Murine Heart Transplant Rejection Is Complement Dependent.
Increased posttransplant ischemia reperfusion injury (IRI) prevents costimulatory blockade induced heart graft survival but mechanisms linking innate and adaptive immunity are poorly understood. Based on…
- « Previous Page
- 1
- …
- 29
- 30
- 31
- 32
- 33
- …
- 40
- Next Page »