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Articles tagged "Age factors"

  • 2015 American Transplant Congress

    Mitochondrial Feedback Mechanisms in Kidney Cell Senescence

    K. De Vusser,1 K. Hochstenbach,2 E. Winckelmans,2 E. Lerut,3 D. Kuypers,1 T. Nawrot,2 M. Naesens.1

    1Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium; 2Centre for Environmental Sciences, Hasselt University, Hasselt, Belgium; 3Department of Pathology, University Hospitals Leuven, Leuven, Belgium.

    BackgroundProgressive DNA damage (telomere attrition) is considered one of the key instigators of ageing. Different models for ageing where DNA damage leads to accelerated senescence…
  • 2015 American Transplant Congress

    The Product of Donor Age and Preoperative MELD, D-MELD, Predicts Surgical Outcomes After LDLT, When Using Small Graft

    A. Tanemura, S. Mizuno, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, M. Usui, H. Sakurai, S. Isaji.

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan.

    Background:Donor-recipient match is recognized as the factor well predicting recipient outcome in deceased donor liver transplantation. The aim of the present study is to evaluate…
  • 2015 American Transplant Congress

    Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens

    K. Omoto,1 D. Toki,1 M. Okumi,1 T. Shimizu,1 H. Ishida,1 K. Honda,2 J. Koike,3 K. Tanabe.1

    1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan; 3Department of Pathology, St. Marianna University, School of Medicine, Kawasaki, Japan.

    OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…
  • 2015 American Transplant Congress

    Excellent Outcomes With Kidney Transplantation for Patients ≥70 Years of Age

    D. Haakinson,1 K. Reddy,1 A. Moss,1 N. Katariya,1 A. Singer,1 A. Mathur,1 J. Huskey,2 H. Khamash,2 R. Heilman.2

    1Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Nephrology, Mayo Clinic Arizona, Phoenix, AZ.

    BackgroundOur aim was to determine the outcomes following kidney transplantation in recipients ≥70 years of age at the time of transplantation.Materials and MethodsWe analyzed data…
  • 2015 American Transplant Congress

    Frailty and Length of Stay in KT Recipients

    M. McAdams DeMarco, E. King, X. Luo, L. Kucirka, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    BACKGROUND: In KT recipients, length of stay (LOS) is associated with early hospital readmission; yet, predictors of KT LOS are unclear.METHODS: Registry-based predictors of KT…
  • 2015 American Transplant Congress

    Change in Frailty Between Evaluation for Kidney Transplantation and Transplantation

    M. McAdams DeMarco, E. King, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore, MD.

    BACKGROUND: Frailty prevalence is high and predicts early hospital readmission, length of stay and mortality in adults of all ages undergoing kidney transplantation (KT). The…
  • 2015 American Transplant Congress

    Frailty in Patients Being Evaluated for Kidney Transplantation

    M. McAdams DeMarco, I. Olorundare, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    BACKGROUND: In patients undergoing hemodialysis, frailty prevalence is high and predicts mortality and hospitalization. Little is known about frailty in patients with ESRD who are…
  • 2015 American Transplant Congress

    Impact of Donor Specific Antibodies in the Older Kidney Transplant Recipient

    S. Patel, J. Loucks-DeVos, R. Knight, S. Kuten, L. Gaber, A. Gaber.

    Houston Methodist Hospital, Houston.

    Recent evidence suggests that renal transplant recipients (RTR) with both rejection and donor specific antibodies (DSA) are at high risk of graft loss. Concurrently, the…
  • 2015 American Transplant Congress

    Liver Transplantation in Children Using Organ Donation After Circulatory Death– An Analysis of the National Registry

    G. El-Gazzaz, K. Hashimoto, M. Fujiki, T. Daigo, C. Quintino, F. Aucejo, D. Kelly, C. Winans, C. Miller, J. Fung, B. Eghtesad.

    Liver Transplant and Hepatobiliary, Cleveland, Cleveland, OH.

    The waiting list mortality rate for children is higher than for adults owing to scarce availability of size-appropriate grafts for liver transplantation(OLT). There is a…
  • 2015 American Transplant Congress

    Transplanting Pediatric Livers Into Adult Recipients Is Associated With Increased Rejection and Decreased Survival

    V. Fleetwood, J. Harris, M. Hertl, E. Chan.

    General Surgery, Division of Transplantation, Rush University Medical Center, Chicago, IL.

    Introduction: Transplantation of pediatric livers to adult recipients, a measure which places the graft at higher risk of hepatic artery thrombosis (HA), is frequently necessitated…
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