ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Frailty in Patients Being Evaluated for Kidney Transplantation

M. McAdams DeMarco, I. Olorundare, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

Johns Hopkins, Baltimore.

Meeting: 2015 American Transplant Congress

Abstract number: C34

Keywords: Age factors, Kidney transplantation, Waiting lists

Session Information

Date: Monday, May 4, 2015

Session Name: Poster Session C: Disparities in Healthcare Access

Session Time: 5:30pm-6:30pm

 Presentation Time: 5:30pm-6:30pm

Location: Exhibit Hall E

Related Abstracts
  • Change in Frailty Between Evaluation for Kidney Transplantation and Transplantation
  • Change in Frailty Status Over Time Among In-Center Hemodialysis ESRD Patients in the ACTIVE/ ADIPOSE Study

BACKGROUND: In patients undergoing hemodialysis, frailty prevalence is high and predicts mortality and hospitalization. Little is known about frailty in patients with ESRD who are being evaluated for kidney transplantation (KT) and whether frailty is associated with being listed for a KT.

METHODS: 1,517 patients being evaluated for KT (excluding patients being evaluated for a live donor KT) were enrolled in a prospective cohort study (January 2009 and May 2014). The Fried frailty score was measured at the time of evaluation (nonfrail=score of 0 or 1; intermediately frail=score of 2; and frail=score ≥3). We tested whether frailty was associated with being listed for KT at JHH after accounting for factors that are known to be associated with listing (age, sex, race, body mass index, education and employment status) using modified Poisson Regression.

RESULTS: At the time of evaluation, 34% were intermediately frail and 24% were frail. 64.7% of patients being evaluated were listed for KT at JHH. Of those who were listed, 23% had received a KT. The median time between evaluation and listing was 3 months (IQR: 1-6 months; range). Frail patients 1.36-fold (95% CI: 1.15-1.61, P<0.001) more likely to not be listed after evaluation for KT even after accounting for other factors.

Frailty at the time of KT evaluation and listing for KT.
  Nonfrail Intermediately frail Frail
% at Evaluation 41.1 34.2 24.7
% Listed 70.8 64.4 55.2
Adjusted RR (95% CI) of listing Reference 1.15 (0.98, 1.36) 1.36 (1.15, 1.61)
There was no difference in the association between frailty and listing for older and younger adults (P for interaction=0.22).

CONCLUSIONS: There is a high prevalence of frailty among patients being evaluated for KT and those who are frail are less likely to be listed for a KT. These findings suggest that although frailty is not being measured as part of routine clinical care, patients who are frail are less likely to have access to KT.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

DeMarco MMcAdams, Olorundare I, Desai N, Dagher N, Lonze B, Montgomery R, Segev D. Frailty in Patients Being Evaluated for Kidney Transplantation [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/frailty-in-patients-being-evaluated-for-kidney-transplantation/. Accessed April 21, 2021.

« Back to 2015 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
    • Assessment of Anti-A and Anti-B Antibody Titers in Different IVIG Preparations: Correlation with Risk for Hemolysis

    Visit Our Partner Sites

    American Transplant Congress (ATC)

    Visit the official site for the American Transplant Congress »

    American Journal of Transplantation

    The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

    American Society of Transplantation (AST)

    An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

    American Society of Transplant Surgeons (ASTS)

    The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

    Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

    Privacy Policy | Terms of Use

    loading Cancel
    Post was not sent - check your email addresses!
    Email check failed, please try again
    Sorry, your blog cannot share posts by email.
    This site uses cookies: Find out more.